Hostname: page-component-8448b6f56d-cfpbc Total loading time: 0 Render date: 2024-04-24T19:53:35.920Z Has data issue: false hasContentIssue false

Application of phenyl salicylate-sepiolite systems as ultraviolet radiation filters

Published online by Cambridge University Press:  09 July 2018

C. del Hoyo
Affiliation:
Departamento de Química Inorgánica, Universidad de Salamanca, Salamanca, Spain
M. A. Vicente
Affiliation:
Instituto de Recursos Naturales y Agrobiología, CSIC, Cordel de Merinas, s/n, Salamanca, Spain
V. Rives*
Affiliation:
Departamento de Química Inorgánica, Universidad de Salamanca, Salamanca, Spain
*
1Corresponding author.

Abstract

The interaction between phenyl salicylate and sepiolite has been studied using drugclay systems obtained by melting and grinding. The samples have been characterized by powder Xray diffraction, differential thermal and thermogravimetric analyses, and Vis-UV and FT-IR spectroscopies. ‘Free’ water molecules are steadily substituted by the drug molecules, without any chemical change as shown by FT-IR. The systems prepared improved the protecting ability of the pure sepiolite or the pure drug against ultraviolet radiation, especially in the so-called ‘C’ range (290-190 nm).

Type
Research Article
Copyright
Copyright © The Mineralogical Society of Great Britain and Ireland 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Comejo, J. & Hermosin, C. (1986) Structural alteration of sepiolite by dry grinding. Clay Miner. 23, 391398.Google Scholar
Del Hoyo, C., Rives, V. & Vicente, M.A. (1993) Interaction of N-Methyl-8-hydroxy quinoline methyl sulphate with sepiolite. Appl. Clay Sci. 8, 3751.CrossRefGoogle Scholar
Del Hoyo, C. (1995) Pharmaceutical∼clay systems: preparation, characterization and application as ultraviolet radiation shelters. PhD thesis, Univ. Salamanca, Spain.Google Scholar
Del Hoyo, C., Rives, V. & Vicente, M.A. (1995) Electronic spectra of phenyl salicylate/ Montmorillonite and sepiolite complexes by grinding and melting. Spec. Lett. 28, 12251234.Google Scholar
Del Hoyo, C., Rives, V. & Vicente, M.A. (1996). Adsorption of melted drugs on smectite. Clays Clay Miner. 44, 424428.CrossRefGoogle Scholar
Hayashi, H., Otsuka, R. & Imai, N. (1969) Infrared study of sepiolite and palygorskite on heating. Am. Miner. 53, 16131624.Google Scholar
Mackenzie, R.C. (1970) Differential Thermal Analysis. Vol. 1. Academic Press, London.Google Scholar
Macginity, J.W. & Lach, J.L. (1976) In vitro adsorption of various pharmaceuticals to montmorillonite. J. Pharm. Sci. 65, 896902.CrossRefGoogle Scholar
Merck Index (1989) 11th Ed., Centennial Edition. Merck and Co., lnc;, Rahway, N.J. USA.Google Scholar
Ogawa, M., Hashizume, T., Kuroda, K. & Kato, C. (1991) Intercalation of 2,2'-Bipyridine and complex formation in the interlayer space of montmorillonite by solid-solid reactions. Inorg. Chem. 30, 584585.Google Scholar
Ogawa, M., Shirai, H., Kuroda, K. & Kato, C. (1992) Solid-state intercalation of naphthalene and anthracene into alkylammonium-montmorillonites. Clays Clay Miner. 40, 485490.CrossRefGoogle Scholar
Porubcan, J.S., Sema, C.J., White, J.L. & Hem, S.L. (1978) Mechanism of adsorption of clinamycin and tetracycline by montmorillonite. J. Pharm. Sci. 47, 10811087.CrossRefGoogle Scholar
Su, K.S.E. & Carstenten, T.J. (1972) Nature of bonding in montmorillonite adsorbates, II: Bonding as an iondipole interaction. J. Pharm. Sci. 61, 420–424.CrossRefGoogle ScholarPubMed
Vicente, M.A., Sanchez-Camazano, M., Sanchez-Martin, M.J., Del Arco, M., Martin, C., Rives, V. & Vicente-Hernandez, J. (1989) Adsorption and desorption of N-Methyl-8-hydroxy quinoline methyl sulfate on smectite and the potental use of the clay-organic product as an ultraviolet radiation collector. Clays Clay Miner. 37, 157163.Google Scholar