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Use of nesiritide in critically ill children with biventricular dysfunction suffering from oliguria despite standard heart-failure management

Published online by Cambridge University Press:  23 December 2015

Bibhuti B. Das ,
Joshua Koch ,
Vivian Dimas ,
Kristine Guleserian  and
Alan Nugent Open the ORCID record for Alan Nugent [Opens in a new window]
Bibhuti B. Das*
Affiliation:
Department of Pediatrics, Children’s Medical Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
Joshua Koch
Affiliation:
Department of Pediatrics, Children’s Medical Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
Vivian Dimas
Affiliation:
Department of Pediatrics, Children’s Medical Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
Kristine Guleserian
Affiliation:
Department of Cardiovascular and Thoracic Surgery, Children’s Medical center, UT Southwestern Medical center, Dallas, Texas, United States of America
Alan Nugent
Affiliation:
Department of Pediatrics, Children’s Medical Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
*
Correspondence to: B. B. Das, MD, Associate Professor, Division of Pediatric Cardiology, Children’s Medical Center, UT Southwestern Medical Center, Dallas, TX 75235, United States of America. Tel: +214 456 6333; Fax: +214 456 7758; E-mail: bdas99@hotmail.com
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Abstract

Although nesiritide has been used in adults with left heart failure, the experience in the paediatric population is limited. We reviewed and analysed our experience with continuous nesiritide infusion as adjunct therapy in children with biventricular dysfunction due to diverse aetiologies and suffering from oliguria despite intravenous diuretics and inotropic therapies for heart-failure management.

Keywords

B-type natriuretic peptidenesiritidepaediatric heart failureleft ventricular assist devicetotal artificial heart
Type
Brief Reports
Information
Cardiology in the Young , Volume 26 , Issue 4 , April 2016 , pp. 819 - 823
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Copyright
© Cambridge University Press 2015 

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