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Role of speckle tracking echocardiography in the assessment of post-repair left ventricular function in patients with late presentation of anomalous origin of the left coronary artery from the pulmonary artery

Published online by Cambridge University Press:  22 August 2014

Gholamhosein Ajami ,
Mohammad R. Edraki ,
Ali R. Moarref ,
Ahmad A. Amirghofran ,
Mohammad Borzouee ,
Hamid Amoozgar ,
Sirous Cheriki  and
Ali M. Shakiba
Gholamhosein Ajami
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran
Mohammad R. Edraki
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran
Ali R. Moarref
Affiliation:
Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Ahmad A. Amirghofran
Affiliation:
Department of Surgery, Division of Cardiac Surgery, Shiraz University of Medical Sciences, Shiraz, Iran
Mohammad Borzouee
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran
Hamid Amoozgar*
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran
Sirous Cheriki
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran
Ali M. Shakiba
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran
*
Correspondence to: Prof. H. Amoozgar, MD, Department of Pediatrics, Namazi Hospital, Shiraz 71937-11351, Iran. Tel: +98 9173111877; Fax:+98 711 6474298; E-mail: amozgah@sums.ac.ir
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Abstract

The aim of this study was to determine the left ventricular myocardial deformation and segmental myocardial dysfunction by speckle tracking echocardiography and tissue Doppler imaging among the operated patients with anomalous origin of the left coronary artery from the pulmonary artery. The study was conducted on 12 patients diagnosed with anomalous origin of the left coronary artery from the pulmonary artery, who had been operated upon between 2001 and 2013 at the medical centres of Shiraz University of Medical Sciences, Shiraz, Iran. The mean age of the patients at the time of surgical correction was 12.6 years ranging from 6 months to 43 years, and the duration of postoperative follow-up was between 1 and 12 years. Comparison of the strain rate between the patients with acceptable ejection fraction and the control group by tissue Doppler imaging showed significant differences between the two groups regarding the lateral wall (p<0.001), but not the septal wall of the left ventricle (p=0.65). Moreover, the strain values by the speckle tracking method revealed significant differences between the patient and the control group regarding the global strain (p=0.016) and anterior, lateral, and posterior segments of the left ventricle. Although postoperative conventional echocardiography revealed normal global left ventricular function with acceptable ejection fraction, abnormal myocardial deformation of the variable segments of the left ventricle with regional and global myocardial dysfunction were well defined by speckle tracking echocardiography.

Keywords

Coronary artery anomalystrain of the myocardiummyocardial dysfunctiondelayed repair
Type
Original Articles
Information
Cardiology in the Young , Volume 25 , Issue 5 , June 2015 , pp. 969 - 975
Copyright
© Cambridge University Press 2014 

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