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Role of anxiety and depression in adolescents with chest pain referred to a cardiology clinic

  • Zahra Khairandish (a1), Leila Jamali (a1) and Saeedeh Haghbin (a2)



We carried out this study in order to evaluate the causes of chest pain in teenagers and the role of anxiety and depression in this age group compared with the normal population.


In this prospective case–control study, all patients aged 11–18 years with chest pain and no history of trauma and referred to a paediatric cardiology clinic from March, 2009–April, 2010 were selected. A chest pain protocol including a detailed history, full physical examination, required blood tests, electrocardiography, and echocardiography was performed for all. The presence of depression and anxiety and their severity were assessed by Beck questionnaires. The patients were compared with age- and sex-matched, randomly selected healthy controls.


In total, 194 patients with a mean age of 14±2 years were selected. The most frequent presentation was idiopathic chest pain (43.3%), followed by the psychological group (29.9%). These groups had no abnormal points in history, physical, and para-clinical tests. Moderate-to-severe depression was found in 45.9% in the patients group, compared with 17.6% of controls, which was statistically significant (p=0.016). Moreover, anxiety was detected in 67.5% of patients versus 15.4% in controls, which is a statistically significant difference (p=0.009). Cardiac chest pain with 9.27% was the most common type of organic causes.


Chest pain during teenage is more prevalent, but not risky. Undergoing a detailed history and full physical examination can help diagnose the causes in the majority of cases. Given the prevalence of a psychological group as well as role of anxiety and depression in most patients, referring to a psychiatrist is suggested.


Corresponding author

Correspondence to: S. Haghbin, MD, Department of Pediatrics, Namazi Hospital, Motaharri Avenue, Zand Blvd, Shiraz 71937-11351, Iran. Tel and Fax: +98 713 647 4298; E-mail:


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Role of anxiety and depression in adolescents with chest pain referred to a cardiology clinic

  • Zahra Khairandish (a1), Leila Jamali (a1) and Saeedeh Haghbin (a2)


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