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Pathogenesis of congenital cardiac malformations and mechanisms of cardiac remodelling

  • Arnold C. G. Wenink (a1) and Adriana C. Gittenberger-de Groot (a1)

Extract

At first sight, the venous and arterial poles of the heart seem to belong to a single structure. This feature is demonstrated by the continuity seen in the fibrous skeleton between the leaflets of the aortic valve with those of both the mitral and tricuspid valves. Moreover, the orifice of the aortic valve is deeply wedged in between the fibrous annuluses supporting the two atrioventricular valves.

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Corresponding author

Correspondence to: Dr Arnold C. G. Wenink, Department of Anatomy and Embryology, PO Box 9602, 2300 RC Leiden, The Netherlands. Tel: +31 71 527 6682; Fax: +31 71 527 6694; E-mail: a.c.g.wenink@lumc.nl

Keywords

Pathogenesis of congenital cardiac malformations and mechanisms of cardiac remodelling

  • Arnold C. G. Wenink (a1) and Adriana C. Gittenberger-de Groot (a1)

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