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Non-compacted myocardium and foetal left isomerism as a hydrops’ aetiology

  • Ilda J. G. Rocha (a1), Rosete M. A. N. Nogueira (a1) and Ana L. C. Carriço (a1)


We present a case report of a pregnant woman with increased risk for trisomy 21 at first-trimester screening, assessed by ultrasonography, that was sent to our hospital. Amniocentesis was performed at 14 weeks and 2 days to obtain foetal karyotype that was normal (46,XX). At 19 weeks and 1 day, foetal hydrops associated with cardiac malformation was detected by routine scan. Foetal echocardiogram revealed a complete auriculoventricular septal defect, non-compacted myocardium, and a bradycardia of 70–90 beats per minute, which lead to the suspicion of left isomerism. Foetal death occurred at 20 weeks and 3 days. Autopsy was consistent with the prenatal diagnosis.


Corresponding author

Correspondence to: Ilda J. G. Rocha, Rua Doutor Francisco Sá Carneiro – Mafamude, 4400-129 Vila Nova de Gaia. Tel: +351 223778100; Fax: +351 919679732; E-mail:


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