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A new discovered gene mutation in a child with dilated cardiomyopathy

Part of: Atrial Septal Defect (ASD) Ventricular Septal Defect (VSD)

Published online by Cambridge University Press:  05 April 2021

Xiaolong Chen Open the ORCID record for Xiaolong Chen [Opens in a new window] ,
Yewei Xie ,
Xiaobing Li ,
Jin Gong ,
Li Shen  and
Rufang Zhang
Xiaolong Chen
Affiliation:
Department of Cardiothoracic Surgery, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Putuo District, Shanghai, China
Yewei Xie
Affiliation:
Department of Cardiothoracic Surgery, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Putuo District, Shanghai, China
Xiaobing Li
Affiliation:
Department of Cardiothoracic Surgery, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Putuo District, Shanghai, China
Jin Gong
Affiliation:
Department of Cardiothoracic Surgery, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Putuo District, Shanghai, China
Li Shen*
Affiliation:
Department of Cardiothoracic Surgery, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Putuo District, Shanghai, China
Rufang Zhang*
Affiliation:
Department of Cardiothoracic Surgery, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Putuo District, Shanghai, China
*
Author for correspondence: Dr L. Shen and Dr R. Zhang, Department of Cardiothoracic Surgery, Shanghai Children’s Hospital, Shanghai Jiao Tong University, No.355 Luding Road, Putuo District, Shanghai200062, China. E-mails: drshenli2018@163.com and zhangrf@shchildren.com.cn
Author for correspondence: Dr L. Shen and Dr R. Zhang, Department of Cardiothoracic Surgery, Shanghai Children’s Hospital, Shanghai Jiao Tong University, No.355 Luding Road, Putuo District, Shanghai200062, China. E-mails: drshenli2018@163.com and zhangrf@shchildren.com.cn
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Abstract

Dilated cardiomyopathy is characterised by dilatation and impaired contraction of the left ventricle or both ventricles, which is the most common childhood cardiomyopathy. In recent years, it has been recognised that many sorts of genetic mutations may contribute to dilated cardiomyopathy. We now report a rare association of dilated cardiomyopathy with site mutation of BMPR2 gene. We did not find such an association reported in the medical literature.

Keywords

Dilated cardiomyopathychildBMPR2gene mutation
Type
Brief Report
Information
Cardiology in the Young , Volume 31 , Issue 9 , September 2021 , pp. 1530 - 1531
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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