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Is there any relationship between platelet indices and myocarditis in children?

Part of: Infectious

Published online by Cambridge University Press:  10 May 2021

Damla Geçkalan Soysal Open the ORCID record for Damla Geçkalan Soysal [Opens in a new window]  and
Rahmi Özdemir
Damla Geçkalan Soysal*
Affiliation:
Kütahya Health Sciences University, Department of Pediatrics, Kütahya, Turkey
Rahmi Özdemir
Affiliation:
Kütahya Health Sciences University, Department of Pediatric Cardiology, Kütahya, Turkey
*
Author for correspondence: Damla Geçkalan Soysal, MD, Department of Pediatrics, Kutahya Health Sciences University Faculty of Medicine, Evliya Çelebi Campus on Tavşanlı Road 10.km Kutahya, Turkey. Tel:+90-50628443654. E-mail: damlageckalan@gmail.com
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Abstract

Background:

Platelet indices are used to evaluate platelet activation and function which change in inflammatory diseases. We hypothesise that platelet indices such as plateletcrit, mean platelet volume, and platelet distribution width may be more useful as prognostic indicators for myopericarditis in children.

Methods:

A total of 60 children were included in this study. Group 1 consists of children with myopericarditis, Group 2 is those with respiratory infections, and Group 3 consists of control group children of similar age and gender with the patient groups. Complete blood count parameters, C-reactive protein, and troponin values of the whole study group were recorded. Myopericarditis was diagnosed based on acute chest pain, dyspnea, palpitations, heart failure signs, arrhythmia symptoms and ST/T wave change, low voltage, supraventricular tachycardia/ventricular tachycardia on ECG, or elevated troponin T/troponin I levels or functional abnormalities on echocardiography. A comparison of the platelet indices made during diagnosis and 2 weeks after treatment was done for the myopericarditis patients.

Results:

There was no statistically significant difference in platelet indicies values. However, the increase in platelets and plateletcrit values after the treatment of myopericarditis was statistically significant. This study pointed out that there was a negative correlation between platelet–plateletcrit values and the troponin I–C-reactive protein.

Conclusion:

We found that platelet count and plateletcrit values increased after treatment. This is important as it is the first study in children to investigate the possible role of platelet indications for myopericarditis in children.

Keywords

Myopericarditsplatelet indiceschildrenplateletcrit
Type
Original Article
Information
Cardiology in the Young , Volume 32 , Issue 2 , February 2022 , pp. 203 - 207
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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