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in vitro experiments and in vivo implants to evaluate a new silicone-based polyurethane material for replacement of small vessels

  • giorgio soldani (a1), massimo bernabei (a2), paola losi (a1), adrian crucean (a2), dante chiappino (a2), silvia burchielli (a3) and fabio bernini (a3)...

Abstract

the idea underscoring our proposed development is to take advantage of the good properties of both polyurethanes (pu) and silicones (pdms). the attributes which make polyurethanes attractive as materials for biomedical applications are their excellent physical–chemical properties, and their relatively good biocompatibility. against their use is the phenomenon of biodegradation that occurs after long-term implantation. silicones, on the other end, are known to have long-term biostability and good haemocompatibility subsequent to their use in several biomedical settings.

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Corresponding author

correspondence to: giorgio soldani, istituto di fisiologia clinica (c.n.r.) – section: “g. pasquinucci” hospital laboratory for biomaterials & graft technology, via aurelia sud – loc. montepepe – 54100 massa, italy. tel/fax: +39 0585 493632; e-mail: giorgio.soldani@ifc.cnr.it

Keywords

in vitro experiments and in vivo implants to evaluate a new silicone-based polyurethane material for replacement of small vessels

  • giorgio soldani (a1), massimo bernabei (a2), paola losi (a1), adrian crucean (a2), dante chiappino (a2), silvia burchielli (a3) and fabio bernini (a3)...

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