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Histological finding of maternal antibody-associated congenital heart block accompanied by large atrial septal defect and severe cardiac dysfunction

Published online by Cambridge University Press:  30 March 2022

Yasuhiro Endo ,
Yoko Kawai Open the ORCID record for Yoko Kawai [Opens in a new window]  and
Masaaki Yamagishi
Yasuhiro Endo
Affiliation:
Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
Yoko Kawai*
Affiliation:
Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan
Masaaki Yamagishi
Affiliation:
Department of Pediatric Cardiovascular Surgery, Children’s Medical Center, Kyoto Prefectural University of Medicine, Kyoto, Japan
*
Author for correspondence: Yoko Kawai, MD, Department of Pediatrics, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan. Tel: +81-75-251-5571; Fax: +81-75-252-1399. E-mail: y-kiwi@koto.kpu-m.ac.jp
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Abstract

Cardiac dysfunction commonly occurs in congenital heart block associated with maternal anti-SSA antibodies, especially after pacemaker implantation. We report the case of a 4-year-old girl with antibody-associated congenital heart block and a large secundum atrial septal defect who presented with significant cardiac dysfunction 4 years after pacemaker implantation. Histological findings were useful for determining the course of treatment and perioperative risk of intracardiac repair.

Keywords

Congenital heart blockmaternal autoimmune antibodyatrial septal defectcardiac dysfunction
Type
Brief Report
Information
Cardiology in the Young , Volume 32 , Issue 12 , December 2022 , pp. 2032 - 2035
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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