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Evaluation of myocardial deformation in patients with Kawasaki disease using speckle-tracking echocardiography during mid-term follow-up

Published online by Cambridge University Press:  05 April 2017

Reyhan Dedeoglu ,
Kenan Barut ,
Funda Oztunc ,
Sezen Atik ,
Amra Adrovic ,
Sezgin Sahin ,
Dicle Cengiz  and
Ozgur Kasapcopur
Reyhan Dedeoglu*
Affiliation:
Pediatric Cardiology, Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital, Siyami Ersek Hospital, Istanbul, Turkey
Kenan Barut
Affiliation:
Pediatric Cardiology, Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital, Siyami Ersek Hospital, Istanbul, Turkey
Funda Oztunc
Affiliation:
Pediatric Cardiology, Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital, Siyami Ersek Hospital, Istanbul, Turkey
Sezen Atik
Affiliation:
Pediatric Cardiology, Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital, Siyami Ersek Hospital, Istanbul, Turkey
Amra Adrovic
Affiliation:
Pediatric Cardiology, Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital, Siyami Ersek Hospital, Istanbul, Turkey
Sezgin Sahin
Affiliation:
Pediatric Cardiology, Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital, Siyami Ersek Hospital, Istanbul, Turkey
Dicle Cengiz
Affiliation:
Pediatric Cardiology, Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital, Siyami Ersek Hospital, Istanbul, Turkey
Ozgur Kasapcopur
Affiliation:
Pediatric Cardiology, Dr. Siyami Ersek Chest, Heart and Vessel Surgery Teaching and Research Hospital, Siyami Ersek Hospital, Istanbul, Turkey
*
Correspondence to: R. Dedeoglu, MD, Department of Pediatric Cardiology, Cerrahpaşa Medical Faculty, Istanbul, Turkey. Tel: +90 506 474 38 58; Fax: +90 (212) 632 00 50; E-mail: reyhandedeoglu@gmail.com
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Abstract

Speckle-tracking echocardiography is a recently developed technique for the evaluation of myocardial deformation or strain. Our objective was to examine strain through a mid-term follow-up of patients with Kawasaki disease.

Methods

We explored left ventricular mechanics using speckle-tracking echocardiography in 35 patients with a history of Kawasaki disease at least 6 months after the acute phase. We also included 30 healthy children as controls. Strain data sets were acquired for the quantification of left ventricular global strain, segmental strain, and left ventricular ejection fraction.

Results

The mean age of our patients was 25.6±15.4 months. At a median follow-up of 57.5 months (16.5–98.2), although both values were in the normal range, the mean left ventricular ejection proportion of patients (57.3%) was a little lower than that of controls (p⩽0.05). Patient strain values at the basal inferoseptal (20.0), basal anterolateral (19.5), apical septal (23.3), and apical inferior (24.0) segments were lower compared with controls. In all, seven patients had coronary aneurysms during follow-up. Kawasaki disease patients with pyuria had lower left ventricular strain at the mid anterior, mid anteroseptal, apical anterior, and apical inferior segments and global longitudinal strain compared with patients with no pyuria (p⩽0.05).

Conclusion

In children with a history of Kawasaki disease, impairment of left ventricular mechanics occurs especially within the left anterior descending artery territories.

Keywords

Myocardial deformationspeckle-tracking echocardiographyKawasaki diseasestrainmyocarditis
Type
Original Articles
Information
Cardiology in the Young , Volume 27 , Issue 7 , September 2017 , pp. 1377 - 1385
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Copyright
© Cambridge University Press 2017 

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