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Complex atrial arrhythmias as first manifestation of catecholaminergic polymorphic ventricular tachycardia: an unusual course in a patient with a new mutation in ryanodine receptor type 2 gene

Published online by Cambridge University Press:  28 August 2013

Wolfgang Lawrenz ,
Otto N. Krogmann  and
Marcus Wieczorek
Wolfgang Lawrenz*
Affiliation:
Clinic for Pediatric Cardiology, Congenital Heart Disease, Heart Center Duisburg, Duisburg, Germany Clinic for Electrophysiology, Evangelic Hospital Dinslaken, Dinslaken, Germany
Otto N. Krogmann
Affiliation:
Clinic for Pediatric Cardiology, Congenital Heart Disease, Heart Center Duisburg, Duisburg, Germany
Marcus Wieczorek
Affiliation:
Clinic for Electrophysiology, Evangelic Hospital Dinslaken, Dinslaken, Germany
*
Correspondence to: W. Lawrenz, MD, Clinic for Pediatric Cardiology, Congenital Heart Disease, Heart Center Duisburg, Gerrickstr. 21, 47137 Duisburg, Germany. Tel: 0049-203-4513301; fax: 0049-203-4513303; E-mail: wolfgang.lawrenz@evkln.de
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Abstract

Catecholaminergic polymorphic ventricular tachycardia is a rare life-threatening arrhythmogenic disorder. An association with paroxysmal atrial fibrillation and other atrial arrhythmias has been described, but in all published cases the initial manifestation of the disease was ventricular arrhythmia. This is the first report about a patient who presented with complex atrial tachycardia and sinus node dysfunction about 1 year before the typical ventricular arrhythmias were observed, leading to the diagnosis of catecholaminergic polymorphic ventricular tachycardia. In this girl, a mutation of the ryanodine receptor type 2 gene, which has not been described so far, was discovered.

Keywords

Catecholaminergic polymorphic ventricular tachycardiaatrial fibrillationryanodine receptor type 2
Type
Brief Reports
Information
Cardiology in the Young , Volume 24 , Issue 4 , August 2014 , pp. 741 - 744
Copyright
Copyright © Cambridge University Press 2013 

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