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Association of matrix metalloproteinase 3 and γ-glutamyltransferase 1 gene polymorphisms with the cardio-ankle vascular index in young Russians

  • Alexander V. Sorokin (a1), Kazuhiko Kotani (a2) and Olga Y. Bushueva (a3)

Abstract

Specific gene polymorphisms are known to be associated with a different arterial physiology in the younger generation. The present study found that young Russians with the matrix metalloproteinase 3 6A/6A and γ-glutamyltransferase 1AA genotypes have lower levels of the cardio-ankle vascular index – a recent measure of arterial stiffness. This observation may serve as an additional tool for cardiovascular disease prevention in the young population.

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Corresponding author

Correspondence to: A. Sorokin, MD, PhD, Department of Internal Medicine, Kursk State Medical University, K. Marx St.3, 305041, Kursk, Russia. Tel: +7 (4712) 58 8132; Fax: +7 (4712) 56 7399; E-mail: drsorokin@hotmail.com

References

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Keywords

Association of matrix metalloproteinase 3 and γ-glutamyltransferase 1 gene polymorphisms with the cardio-ankle vascular index in young Russians

  • Alexander V. Sorokin (a1), Kazuhiko Kotani (a2) and Olga Y. Bushueva (a3)

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