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Left atrial thrombosis with invasive pulmonary aspergillosis in children with immunodeficiency

Published online by Cambridge University Press:  28 September 2022

Kyoung Sung Yun
Affiliation:
Department of Pediatrics, Seoul National University Hospital, Seoul, South Korea
Hye Won Kwon*
Affiliation:
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, South Korea
Jae Gun Kwak
Affiliation:
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, South Korea
June Dong Park
Affiliation:
Department of Pediatrics, Seoul National University Hospital, Seoul, South Korea
Jaemoon Koh
Affiliation:
Department of Pathology, Seoul National University Hospital, Seoul, South Korea
*
Author for correspondence: Hye Won Kwon, M.D., Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea. Tel: +82 2 2072 4306; Fax: +82 2 747 2471. E-mail: drhwkwon@gmail.com

Abstract

Invasive aspergillosis is a major cause of infectious disease in immunocompromised patients; however, cardiac involvement in pulmonary aspergillosis is not well-known. Two paediatric patients undergoing chemotherapy were diagnosed with cardiac aspergilloma, accompanied by pulmonary aspergillosis. In both patients, antibiotic and antifungal treatments were initiated immediately after the pneumonia was diagnosed; however, both died of multiple cerebral thromboembolisms.

Type
Brief Report
Copyright
© The Author(s), 2022. Published by Cambridge University Press

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References

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