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Aortic dilation in adults with repaired tetralogy of Fallot: a single-centre study

Published online by Cambridge University Press:  27 February 2024

Tahereh Saedi ,
Rashide Siami ,
Amir J. Ghaffari ,
Danial Farmani  and
Sedigheh Saedi Open the ORCID record for Sedigheh Saedi [Opens in a new window]
Tahereh Saedi
Affiliation:
Iran University of Medical Sciences, Tehran, Iran
Rashide Siami
Affiliation:
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Amir J. Ghaffari
Affiliation:
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Danial Farmani
Affiliation:
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Sedigheh Saedi*
Affiliation:
Congenital Heart Disease Research Center, Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
*
Corresponding author: S. Saedi; Email: sedsaedi@gmail.com
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Abstract

Background:

Tetralogy of Fallot is the most prevalent cyanotic CHD. With the advent of advanced surgical methods, the majority of tetralogy of Fallot patients reach adulthood. However, many need re-intervention for the residual anomalies including residual right ventricular outflow obstruction, pulmonary regurgitation, residual ventricular septal defects, and progressive aortic dilatation. Aortic dilation could lead to aortic regurgitation or dissection requiring surgical correction. In the current study, we aimed to determine the prevalence and outcomes of aortic root dilatation in adults with repaired tetralogy of Fallot in our tertiary care centre.

Methods:

In this retrospective study, 730 consecutive patients with history of repaired tetralogy of Fallot were included. Aortic diameter at the level of annulus, the sinus of Valsalva, sinotubular junction, and the ascending aorta as measured by echocardiography were evaluated. Prevalence of outcomes necessitating re-intervention including aortic regurgitation and dissection were recorded.

Results:

The mean size of annulus, sinus of Valsalva, sinotubular-junction, and ascending aorta in the latest available echocardiography of patients were 2.4+/-0.4 cm, 3.3+/-0.5 cm, 2.9+/-0.5cm, and 3.2+/-0.5cm, respectively. Prevalence of dilatation of sinus of Valsalva, dilation of Ascending aorta, sinotubular-junction, and aortic annulus was 28.7%, 21%, 8.3%, and 1 %, respectively. Five patients had severe aortic regurgitation (0.6%) and underwent surgical repair. One of these patients presented with acute aortic dissection.

Conclusion:

Aortic dilation is common in tetralogy of Fallot but prevalence of redo surgery for aortic dilation, regurgitation, and adverse events including acute dissection is low.

Keywords

Tetralogy of Fallotsurgeryaortaaortic dissectionCHD
Type
Brief Report
Information
Cardiology in the Young , First View , pp. 1 - 3
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Copyright
© The Author(s), 2024. Published by Cambridge University Press

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