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Patient-Reported Benefits of Extracranial Venous Therapy: British Columbia CCSVI Registry

  • A. Dessa Sadovnick (a1) (a2), Irene M. Yee (a1), Kristen Attwell-Pope (a3), Glenn Keyes (a4), Lucas Kipp (a2) (a5) and Anthony L. Traboulsee (a2)...

Abstract

Objective Chronic cerebrospinal venous insufficiency (CCSVI) has been hypothesized to be a risk factor for multiple sclerosis (MS). Venoplasty has been proposed as a treatment for CCSVI. The aim of our study was to gain a better understanding of the “real-world” safety and longitudinal effectiveness of venoplasty Methods: British Columbia residents who self-reported having had venoplasty and consented to participate in the study were interviewed and followed for up to 24 months post-therapy using standardized structured questionnaires Results: Participants reported procedure-related complications (11.5%) and complications within the first month after the procedure (17.3%). Initially, more than 40% of participants perceived that the venoplasty had had positive effects on their health conditions, such as fatigue, numbness, balance, concentration/memory and mobility. However, this improvement was not maintained over time Conclusions: Follow-up patient-reported outcomes indicated that the initial perception of the positive impact of venoplasty on the health conditions of MS patients was not sustained over time. In addition, venoplasty was not without associated morbidity.

Bénéfices rapportés par les patients qui ont subi la thérapie veineuse extracrânienne : le British Columbia CCVI Registry. Objectif : Une hypothèse a été émise selon laquelle l’insuffisance veineuse céphalo-rachidienne chronique serait un facteur de risque de la sclérose en plaques (SP) et la veinoplastie a été proposée comme traitement. Le but de notre étude était de connaître quelle est la sécurité réelle de cette intervention ainsi que son efficacité longitudinale. Méthodologie : Les résidents de la Colombie-Britannique, qui avaient rapporté eux-mêmes avoir subi une veinoplastie et qui ont consenti à participer à l’étude, ont été interviewés et ils ont été suivis au moyen de questionnaires structurés standardisés au cours d’une période allant jusqu’à 24 mois après avoir subi le traitement. Résultats : Des complications reliées à l’intervention ont été rapportées par 11,5% des participants et des complications au cours du premier mois après avoir subi l’intervention par 17,3% d’entre eux. Initialement, plus de 40% des participants considéraient que la veinoplastie avait eu des effets positifs sur leurs problèmes de santé, tels la fatigue, les engourdissements, les problèmes d’équilibre, de concentration/de mémoire et de mobilité. Cependant, cette amélioration n’a pas persisté. Conclusions : Au cours du suivi, les bénéfices rapportés par les patients atteints de SP et la perception initiale de l’impact positif de la veinoplastie sur leurs problèmes de santé ne se sont pas maintenus dans le temps. De plus, la veinoplastie a donné lieu à une certaine morbidité.

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Copyright

Corresponding author

Correspondence to: Anthony L. Traboulsee, Department of Medicine (Neurology), UBC Hospital, University of British Columbia, 2211 Wesbrook Mall, Room S113, Vancouver, British Columbia, Canada V6T 2B5. Email: t.traboulsee@ubc.ca.

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Patient-Reported Benefits of Extracranial Venous Therapy: British Columbia CCSVI Registry

  • A. Dessa Sadovnick (a1) (a2), Irene M. Yee (a1), Kristen Attwell-Pope (a3), Glenn Keyes (a4), Lucas Kipp (a2) (a5) and Anthony L. Traboulsee (a2)...

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