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Pallidal Deep Brain Stimulation in Cervical Dystonia: Clinical Outcome in Four Cases

Published online by Cambridge University Press:  02 December 2014

H.A. Eltahawy ,
J. Saint-Cyr ,
Y.Y. Poon ,
E. Moro ,
A.E. Lang  and
A.M. Lozano
H.A. Eltahawy
Affiliation:
Toronto Western Hospital, Division of Neurosurgery, Toronto, Ontario, Canada and the Ain Shams University Hospitals, Neurosurgery Department, Cairo, Egypt
J. Saint-Cyr
Affiliation:
Toronto Western Hospital, Division of Neurosurgery, Toronto, Ontario, Canada
Y.Y. Poon
Affiliation:
Toronto Western Hospital, Neurology Department, Toronto, Ontario, Canada
E. Moro
Affiliation:
Toronto Western Hospital, Neurology Department, Toronto, Ontario, Canada
A.E. Lang
Affiliation:
Toronto Western Hospital, Neurology Department, Toronto, Ontario, Canada
A.M. Lozano
Affiliation:
Toronto Western Hospital, Division of Neurosurgery, Toronto, Ontario, Canada
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Abstract

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Objective:

Report on the clinical results following bilateral globus pallidus interna deep brain stimulation in four patients (one female and three males) with severe cervical dystonia, mean age 48 years (range 37-67).

Methods:

All four patients had failed extensive medical and botulinum toxin treatment. The mean duration of the disease was nine years (range 4-15 years). Patients were assessed pre and postoperatively using the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS). Preoperatively, the mean TWSTRS total score was 43.2 (range 28-60.5). Posteroventral pallidal deep brain stimulators were inserted using MRI and microelectrode recording guidance. Last follow-up was 15 months for the four patients.

Results:

Mean reduction in the TWSTRS total scores at last follow- up was 73% (range 61- 85%). Improvement in pain occurred soon after deep brain stimulation surgery. Motor improvement was delayed and prolonged over several months. Frequent adjustment in the stimulation parameters was necessary in the first three months.

Conclusion:

Bilateral pallidal stimulation is effective in management of selected cases of intractable cervical dystonia.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 31 , Issue 3 , August 2004 , pp. 328 - 332
Copyright
Copyright © The Canadian Journal of Neurological 2004

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