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P.048 International MAGNIMS-CMSC-NAIMS consensus recommendations on the use of standardized MRI in MS

Published online by Cambridge University Press:  05 January 2022

A Traboulsee
Affiliation:
(Vancouver)*
M Wattjes
Affiliation:
(Hannover)
O Ciccarelli
Affiliation:
(London)
D Reich
Affiliation:
(Bethesda)
B Banwell
Affiliation:
(Philadelphia)
N de Stefano
Affiliation:
(Siena)
C Enzinger
Affiliation:
(Graz)
F Fazekas
Affiliation:
(Graz)
M Filippi
Affiliation:
(Milan)
J Frederiksen
Affiliation:
(Copenhagen)
C Gasperini
Affiliation:
(Roma)
Y Hacohen
Affiliation:
(London)
L Kappos
Affiliation:
(Basel)
DK Li
Affiliation:
(Vancouver)
K Mankad
Affiliation:
(London)
X Montalban
Affiliation:
(Barcelona)
S Newsome
Affiliation:
(Baltimore)
J Oh
Affiliation:
(Toronto)
J Palace
Affiliation:
(Oxford)
M Rocca
Affiliation:
(Milan)
J Sastre-Garriga
Affiliation:
(Barcelona)
M Tintore
Affiliation:
(Barcelona)
H Vrenken
Affiliation:
(Amsterdam)
T Yours
Affiliation:
(London)
F Barkhof
Affiliation:
(London)
A Rovira
Affiliation:
(Barcelona)
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Abstract

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Background: Standardized magnetic resonance imaging (MRI) guidelines published in 2015 by the Europoean MAGNIMS group and in 2016 by the CMSC are important for the diagnosis and monitoring of patients with multiple sclerosis (MS) and for the appropriate use of MRI in routine clinical practice. Methods: Two panels of experts convened to update existing guidelines for a standardized MRI protocol. The MAGNIMS panel convened in Graz, Austria in April 2019. The CMSC NAIMS panel met separately and independently in Newark, USA in October 2019. Subsequently, the MAGNIMS, NAIMS, and CMSC working groups combined their efforts to reach an international consensus Results: The revised guidelines on MRI in MS merges recommendations from MAGNIMS, CMSC, and NAIMS to improve the use of MRI for diagnosis, prognosis and monitoring of individuals with MS. 3D acquisitions are emphasized for optimal comparison over time. Core brain sequences include a 3D-T2wFLAIR for lesion identification and monitoring treatment effectiveness. Gadolinium-based contrast is recommended for diagnostic studies and judicious use for routine monitoring of MS patients. DWI sequences are recommended for PML safety monitoring. Conclusions: The international consensus guidelines strive for global acceptance of a useful and usable standard of care for patients with MS.

Type
Poster Presentations
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of Canadian Neurological Sciences Federation