Hostname: page-component-8448b6f56d-42gr6 Total loading time: 0 Render date: 2024-04-19T12:00:18.228Z Has data issue: false hasContentIssue false
  • English
  • Français

Complications of First Craniotomy for Intra-Axial Brain Tumour

Published online by Cambridge University Press:  18 September 2015

Alberto M. Cabantog  and
Mark Bernstein
Alberto M. Cabantog*
Affiliation:
Division of Neurosurgery, The Toronto Hospital. University of Toronto, Toronto
Mark Bernstein
Affiliation:
Division of Neurosurgery, The Toronto Hospital. University of Toronto, Toronto
*
Division of Neurosurgery, The Toronto Hospital, 2-405 McLaughlin Pavilion, 399 Bathurst Street, Toronto, Ontario, Canada M5T2S8
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Complications were examined in a single surgeon’s series of 207 consecutive adult patients undergoing first craniotomy for intra-axial brain tumour. The study group consisted of 114 gliomas, 74 metastatic tumours and 19 miscellaneous lesions. There were 25 infratentorial tumours and 182 supratentorial tumours (39 deep and 143 superficial). The total number of patients sustaining complications was 52 for an overall complication rate of 25.1%; the rate was higher for infratentorial tumours (44.0%) than supratentorial tumours (22.8%) regardless of histology (p = 0.012). There were 5 deaths for a mortality rate of 2.4%. Forty-seven patients incurred operative morbidity (22.7%); 7 out of the 47 had multiple complications. Sixteen patients sustained transient worsening due to edema (7.7%) and 6 patients sustained permanent neurological deficit (2.9%). Medical complications were suffered by 17 patients (8.2%). Major complications which significantly altered the quality and/or quantity of survival were suffered by 9 patients overall (4.3%).

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 21 , Issue 3 , August 1994 , pp. 213 - 218
Copyright
Copyright © Canadian Neurological Sciences Federation 1994

References

1.Olivecrona, H.The surgical treatment of intracranial tumors. In: Olivecrona, H, Tonnis, E.Handbuch der Neurochirurgie. Berlin: Springer Verlag, 1967; 1–101.Google Scholar
2.Housepian, EM.Role of neurosurgery in the management of supratentorial gliomas. In: Chang, CH, Housepian, EM.Tumors of the Central Nervous System: Modern Radiotherapy Multi-disciplinary Management. New York: Masson, 1982; 18–32.Google Scholar
3.Cushing, H.Intracranial Tumours: Notes Upon a Series of Two Thousand Verified Cases with Surgical-Mortality Percentages Pertaining Thereto. Springfield, 111.: Charles C Thomas, 1932.Google Scholar
4.Hitchcock, E, Sato, F.Treatment of malignant gliomata. J Neurosurg 1964; 21:497–505.CrossRefGoogle ScholarPubMed
5.Jelsma, R, Bucy, PC.The treatment of glioblastoma multiforme of the brain. J Neurosurg 1967; 27: 388–400.CrossRefGoogle ScholarPubMed
6.Roth, JG, Elvidge, AR.Glioblastoma multiforme: a clinical survey. J Neurosurg 1960; 17: 736–750.CrossRefGoogle ScholarPubMed
7.Salcman, M.Surgical decision making for malignant brain tumors. Clin Neurosurg 1989; 35: 285–313.Google ScholarPubMed
8.Kelly, PJ, Daumas-Duport C, Kispert, DB, et al. Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms. J Neurosurg 1987; 66: 865–874.CrossRefGoogle ScholarPubMed
9.Nazzaro, JM.Neuwelt, EA.The role of surgery in the management of supratentorial intermediate and high-grade astrocytomas in adults. J Neurosurg 1990; 73: 331–344.CrossRefGoogle ScholarPubMed
10.Ammirati, M, Vick, N, Liao, Y, et al. Effect of the extent of surgical resection on survival and quality of life in patients with supratentorial glioblastomas and anaplastic astrocytomas. Neurosurgery 1987; 21: 201–206.CrossRefGoogle ScholarPubMed
11.Brega, K, Robinson, WA, Winston, K, et al. Surgical treatment of brain metastases in malignant melanoma. Cancer 1990; 66: 2105–2110.3.0.CO;2-I>CrossRefGoogle ScholarPubMed
12.Ciric, I, Ammirati, M, Vick, N, et al. Supratentorial gliomas: surgical considerations and immediate postoperative results; gross total resection versus partial resection. Neurosurgery 1987; 21: 21–26.CrossRefGoogle ScholarPubMed
13.Devaux, BC, O’Fallon, J, Kelly, PJ.Resection, biopsy, and survival in malignant glial neoplasms: a retrospective study of clinical parameters, therapy and outcome. J Neurosurg 1993; 78: 767–775.CrossRefGoogle ScholarPubMed
14.Galicich, JH, Sundaresan, N.Metastatic brain tumors. In: Wilkins, RH, Rengachary, SS.Neurosurgery. New York: McGraw-Hill, 1985; 597–610.Google Scholar
15.Guazzo, EP, Atkinson, AT, Weidman, M, et al. Management of solitary melanoma metastasis of the brain. Aust N Z J Surg 1989; 59:321–324.CrossRefGoogle ScholarPubMed
16.Höllerhage, HG, Zumkeller, M, Becker, M, et al. Influence of type and extent of surgery on early results and survival time in glioblastoma multiforme. Acta Neurochir 1991; 113: 31–37.CrossRefGoogle ScholarPubMed
17.Kelly, PJ.Stereotactic biopsy and resection of thalamic astrocytomas. Neurosurgery 1989; 25: 185–195.CrossRefGoogle ScholarPubMed
18.Kelly, PJ, Kail, BA, Goerss, SJ.Results of computed tomography-based computer-assisted stereotactic resection of metastatic intracranial tumors. Neurosurgery 1988; 22: 7–17.CrossRefGoogle ScholarPubMed
19.Kreth, FW, Warnke, PC, Scheremet, R, et al. Surgical resection and radiation therapy versus biopsy and radiation therapy in the treatment of glioblastoma multiforme. J Neurosurg 1993; 78: 762–766.CrossRefGoogle ScholarPubMed
20.McCormack, BM, Miller, DC, Budzilovich, GN, et al. Treatment and survival of low-grade astrocytoma in adults – 1977–1988. Neurosurgery 1992; 31: 636–642.Google ScholarPubMed
21.Paoletti, P, Butti, G, Spanu, G.Surgery of cerebral gliomas. State of the art. Dev Oncol 1991; 66: 129–136.Google Scholar
22.Patchell, RA, Tibbs, PA, Walsh, JW, et al. A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 1990; 322:494–500.CrossRefGoogle ScholarPubMed
23.Philippon, JH, Clemenceau, SH, Fauchon, FH, et al. Supratentorial low-grade astrocytomas in adults. Neurosurgery 1993; 32: 554–559.CrossRefGoogle ScholarPubMed
24.Sundaresan, N, Galicich, JH.Surgical treatment of brain metastases: clinical and computerized tomography evaluation of the results of treatment. Cancer 1985; 55: 1382–1388.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
25.Sundaresan, N, Galicich, JH, Beattie, EI.Surgical treatment of brain metastases from lung cancer. J Neurosurg 1983; 58: 666–671.CrossRefGoogle ScholarPubMed
26.Vecht, CJ, Avzaat, CJ, van Putten, WL, et al. The influence of the extent of surgery on the neurological function and survival in malignant glioma: a retrospective analysis in 243 patients. J Neurol Neurosurg Psychiatry 1990; 53: 466–471.CrossRefGoogle ScholarPubMed
27.Winston, KR, Walsh, JW, Fischer, EG.Results of operative treatment of intracranial metastatic tumors. Cancer 1980; 45: 2639–2645.3.0.CO;2-O>CrossRefGoogle ScholarPubMed
28.Fadul, C, Wood, J, thaler, H, et al. Morbidity and mortality of craniotomy for excision of supratentorial gliomas. Neurology 1988; 38: 1374–1379.CrossRefGoogle ScholarPubMed
29.Black, P.Brain metastasis: current status and recommended guidelines for management. Neurosurgery 1979; 5: 617–663.CrossRefGoogle ScholarPubMed
30.Andrews, RJ, Bringas, JR.A review of brain retraction and recommendations for minimizing intraoperative brain injury. Neurosurgery 1993; 33: 1052–1064.Google ScholarPubMed
31.North, JB, Penhall, RK, Hanieh, A, et al. Phenytoin and postoperative epilepsy: a double blind study. J Neurosurg 1983; 58: 672–677.CrossRefGoogle ScholarPubMed
32.Shaw, MDM.Post-operative epilepsy and the efficacy of anticonvulsant therapy. Acta Neurochir, Suppl 1990; 50: 55–57.Google ScholarPubMed
33.Levi, A, Wallace, C, Bernstein, M, et al. Venous thromboembolism after brain tumor surgery: a retrospective review. Neurosurgery 1991: 28: 859–863.CrossRefGoogle ScholarPubMed