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Antagonism by Taurine of Morphine Induced Growth Hormone Secretion

Published online by Cambridge University Press:  18 September 2015

R. Collu ,
G. Charpenet  and
M. J. Clermont
R. Collu
Affiliation:
Centre de Recherche Pédiatrique, Hôpital Sainte-Justine and Université de Montréal, Montréal, Quebéc
G. Charpenet
Affiliation:
Centre de Recherche Pédiatrique, Hôpital Sainte-Justine and Université de Montréal, Montréal, Quebéc
M. J. Clermont
Affiliation:
Centre de Recherche Pédiatrique, Hôpital Sainte-Justine and Université de Montréal, Montréal, Quebéc
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The intraperitoneal (IP) or intraventricular (IVT) administration of small amounts of taurine did not modify pentobarbital-induced sleep or pituitary hormone release. However, the drastic increment in plasma GH values induced by morphine administration was completely blocked by the IVT injection of the amino acid. Whether taurine plays a physiological role in the control ofGH secretion is highly speculative.

Type
Quebec Cooperative Study of Friedreich's Ataxia
Information
Canadian Journal of Neurological Sciences , Volume 5 , Issue 1 , February 1978 , pp. 139 - 142
Copyright
Copyright © Canadian Neurological Sciences Federation 1978

References

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