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Adult-Onset Anti-N-methyl-D-aspartate-receptor Encephalitis Presenting as a Non-Fluent Aphasia

  • Julien Hébert (a1), Farah El-Sadi (a1), Catherine Maurice (a2), Richard A. Wennberg (a3) and David F. Tang-Wai (a3)...
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Abstract

Copyright

Corresponding author

Correspondence to: Julien Hébert, Toronto Western Hospital, 399 Bathurst, St. 5WW441, Toronto, ON, Canada M5T 2S8. Email: julien.hebert@mail.utoronto.ca

References

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1. Taylor, R, Mason, W, Kong, K, Wennberg, RA. Reversible paraneoplastic encephalomyelitis associated with a benign ovarian teratoma. Can J Neurol Sci. 1999;26:317-320.
2. Dalmau, J, Tüzün, E, Wu, H, et al. Paraneoplastic anti–N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol. 2007;61:25-36.
3. Dalmau, J, Gleichman, AJ, Hughes, EJ, et al. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol. 2008;7:1091-1098.
4. Wang, W, Li, J-M, Hu, F-Y, et al. Anti-NMDA receptor encephalitis: clinical characteristics, predictors of outcome and the knowledge gap in southwest China. Eur J Neurol. 2015;23:621-629.
5. Titulaer, MJ, McCraken, L, Iñigo, G, et al. Late-onset anti–NMDA receptor encephalitis. Neurology. 2013;81:1058-1063.
6. Vahter, L, Kannel, K, Sorro, U, Jaakmees, H, Talvik, T, Gross-Paju, K. Cognitive dysfunction during anti-NMDA-receptor encephalitis is present in early phase of the disease. Oxf Med Case Reports. 2014;7:74-76.
7. Florance, NR, Davis, RL, Lam, C, Szperka, C, Zhou, L, Ahmad, S. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol. 2009;66:11-118.
8. Kumaran, D, Pera, MC, Maurey, H, Chrétien, P, Archambaud, F, Bouilleret, V. Sudden and isolated Broca’s aphasia: a new clinical phenotype of anti NMDA receptor antibodies encephalitis in children. Eur J Paediatr Neurol. 2014;18:790-792.
9. Leon-Salas, JM, Rosas, R, Diaz-Victoria, AR, Flores, J, Ojeda-Lopez, C, Espinola-Nadurille, M. Cortical aphasia and apraxia as main clinical presentation of anti-NMDAR encephalitis relapse with a positive CSF PCR for cytomegalovirus. Neuropsychiatry. 2017;7:620-628.

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