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Treatment of Stroke in Canadian Emergency Departments: Time to be Leaders

  • Devin R. Harris (a1) (a2), Eddy S. Lang (a3), Jeffery J. Perry (a4) and Laurie J. Morrison (a5)
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Abstract

Copyright

Corresponding author

Correspondence to: Dr. Devin Harris, Head, Department of Emergency Medicine, Kelowna General Hospital, 2268 Pandosy Avenue, Kelowna, BC, V1Y1T2; Email: Devin.Harris@interiorhealth.ca

References

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1. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue Plasminogen Activator for Acute Ischemic Stroke. N Engl J Med 1995;333(24):1581-1587.
2. Katzan, IL, Furlan, AJ, Lloyd, LE, et al. Use of tissue-type plasminogen activator for acute ischemic stroke: the Cleveland area experience. JAMA 2000;283(9):1151-1158.
3. Hoffman, JR, Schriger, DL. A graphic re-analysis of the NINDS trial. Ann Emerg Med 2009;54(3):329-336.
4. Newman, DH. Thrombolytics for acute ischemic stroke. The NNT: The NNT Group; 2010. Available from: http://www.thennt.com/thrombolytics-for-stroke (accessed July 2015).
5. Canadian Association of Emergency Physicians Committee on Thrombolytic Therapy for Acute Ischemic Stroke. Thrombolytic therapy for acute ischemic stroke. CJEM 2001;3(1):8-12.
6. Johnstone, C. Thrombolysis for acute ischemic stroke: does it work?—the con position. CJEM 2015;17(2):180-183.
7. Hacke, W, Kaste, M, Bluhmki, E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008;359(13):1317-1329.
8. IST-3 Collaborative Group, Sandercock, P, Wardlaw, JM, et al. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet 2012;379(9834):2352-2363.
9. Harris, D, Hall, C, Lobay, K, et al. Canadian Association of Emergency Physicians Position Statement on Acute Ischemic Stroke. CJEM 2015;17(2):217-226.
10. Goyal, M, Demchuk, AM, Menon, BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015;372(11):1019-1030.
11. Berkhemer, OA, Fransen, PSS, Beumer, D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015;372(1):11-20.
12. Campbell, BCV, Mitchell, PJ, Kleinig, TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372(11):1009-1018.
13. Saver, JL, Goyal, M, Bonafe, A, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015;372(24):2285-2295.
14. Jovin, TG, Chamorro, A, Cobo, E, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 2015;372(24):2296-2306.
15. Furlan, AJ. Endovascular therapy for stroke—it’s about time. N Engl J Med 2015;372(24):2347-2349.
16. Harris, D, Teal, P, Turton, M, et al. Stroke Education in Canadian Emergency Medicine Residency Programs. CJEM 2016;18(4):XXX.
17. Sandercock, P, Counsell, C, Tseng, MC, et al. Oral antiplatelet therapy for acute ischaemic stroke. Cochrane Database Syst Rev 2014;3:CD000029.
18. Stroke Unit Trialists’ Collaboration. Organised inpatient (stroke unit) care for stroke. Cochrane Database Syst Rev 2013;9:CD000197.
19. Lindsay, P, Bayley, M, Hellings, C, et al. Canadian best practice recommendations for stroke care: summary (updated 2010). CMAJ 2008;17(12 Suppl):S1-25.
20. Langhorne, P, de Villiers, L, Pandian, JD. Applicability of stroke-unit care to low-income and middle-income countries. Lancet Neurol 2012;11(4):341-348.
21. Rothwell, PM, Giles, MF, Chandratheva, A, et al. Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison. Lancet 2007;370(9596):1432-1442.
22. Coutts, SB, Wein, TH, Lindsay, MP, et al. Canadian Stroke Best Practice Recommendations: secondary prevention of stroke guidelines, update 2014. Int J Stroke 2015;10(3):282-291.
23. Kamal, N, Hill, MD, Blacquiere, DP, et al. Rapid Assessment and Treatment of Transient Ischemic Attacks and Minor Stroke in Canadian Emergency Departments: Time for a Paradigm Shift. Stroke 2015;46(10):2987-2990.
24. Kamal, N, Lindsay, P, Cote, R, et al. Ten-year trends in stroke admissions and outcomes in Canada. Can J Neurol Sci 2015;42(3):168-175.

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