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Field trials of double translocation heterozygote males for genetic control of Aedes aegypti (L.) (Diptera: Culicidae)

  • J. L. Petersen (a1), L. P. Lounibos (a1) and Nancy Lorimer (a1)


For nine weeks from 14 April to 13 June 1975 an average of over 500 double translocation heterozygote male Aedes aegypti (L.) were released daily into a village where the estimated adult mosquito population was 1200. The two purposes of this release were to suppress the A. aegypti population by sterility induced by chromosomal translocations and to assess the effect of rainy season conditions on the population dynamics of the indigenous and released mosquitoes. As a result of the releases, hatchabirity of eggs from females collected during landing-biting catches dropped from over 93% to 30–40%. For eight weeks following the termination of the releases, hatchability remained below 70% while that of the reference village averaged between 80 and 99% hatch. A relative population decline observed in the release village is not attributed solely to the effect of the releases, partly because it occurred before sufficient time had elapsed to allow induced sterility to build up in the field population.



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Craig, G. B., Hickey, W. A.. (1967). Genetics of Aedes aegypti. pp. 67131 in Wright, J. W., Pal, R.. (Eds). Genetics of insect vectors of Disease. — 794 pp. Amsterdam, Elsevier.
Curtis, C. F.. (1968). A possible genetic method for the control of insect pests, with special reference to tsetse flies (Glossina spp.). — Bull. ent. Res. 57, 509523.
Curtis, C. F.., Grover, K. K.., Suguna, S. G.., Uppal, D. K.., Dietz, K.., Agarwal, H. V., Kazmi, S. J.. (1976). Comparative fieldcagetestsofthe population suppressing efficiency of three genetic control systems for Aedes aegypti. — Heredity. 36, 1129.
Davidson, G.. (1974). Genetic control of insect pests. — 158 pp. London, Academic Press.
Grover, K. K.., Suguna, S. G.., Uppal, D. K.., Singh, K. R. P.., Ansari, M. A.., Curtis, C. F.., Singh, D.., Sharma, V. P., Panicker, K. N. (1976). Field experiments on the competitiveness of males carrying genetic control systems for Aedes aegypti. — Entomologia exp. appl. 20, 818.
Hallinan, E.., Lorimer, N., Rai, K. S.. (1976). Genetic manipulation of Aedes aegypti. II. A cytogenetic study of radiation induced translocations in DELHI strain. — Proc. XV Int. Congr. Ent. August 19–27, 1976, Washington, D.C., U.S.A., pp. 117128.
Hartberg, W. K.. (1971). Observations on the mating behaviour of Aedes aegypti in nature. — Bull. Wld Hlth Org. 45, 847850.
Jolly, G. M.. (1965). Explicit estimates from capture-recapture data with both death and immigration-stochastic model. — Biometrika. 52, 225247.
Lorimer, N.., Lounibos, L. P., Petersen, J. L. (1976). Field trials with a translocation homozygote in Aedes aegypti for population replacement. — J. econ. Ent. 69, 405409.
Mattingly, P. F.. (1957). Genetical aspects of the Aedes aegypti problem I.—Taxonomy and bionomics. — Ann. trop. Med. Parasit. 51, 392408.
McDonald, P. T.., Hauserman, W., Lorimer, N.. (in press). Sterility introduced by release of genetically altered males to a domestic population of Aedes aegypti at the Kenya coast. — Am. J. Trop. Med. Hyg.
McDonald, P. T., Rai, K. S.. (1971). Population control potential of heterozygous trans-locations as determined by computer simulations. — Bull Wld Hlth Org. 44, 829845.
Rai, K. S., Asman, M.. (1968). Possible application of a reciprocal translocation for genetic control of the mosquito, Aedes aegypti. — Proc. XII int. Congr. Genetics. 1, 164.
Rai, K. S.., Grover, K. K., Suguna, S. G.. (1973). Genetic manipulation of Aedes aegypti: incorporation and maintenance of a genetic marker and a chromosomal translocation in natural populations. — Bull. Wld Hlth Org. 48, 4956.
Rai, K. S.., Lorimer, N., Hallinan, E. M.. (1974). The current status of genetic methods for controlling Aedes aegypti. pp. 119132 in Pal, R., Whitten, M. J.. (Eds). The use of genetics in insect control.— 241 pp.Amsterdam, Elsevier/North-Holland.
Rai, K. S.., Mcdonald, P. T., Ashman, S. M.. (1970). Cytogenetics of two radiation-induced, sex-linked translocations in the yellow-fever mosquito, Aedes aegypti. — Genetics, Princeton. 66, 635651.
Robinson, A. S.. (1976). Progress in the use of chromosomal translocations for the control of insect pests. — Biol. Rev. 51, 124.
Seawright, J. A.., Kaiser, P. E.., Jinling, Y. E. H., Stevenson, H. R.. (1975a). Reciprocal translocations in Aedes aegypti (L.). — Mosq. News. 35, 384388.
Seawright, J. A.., Kaiser, P. E.., Dame, D. A., Willis, N. L.. (1975b). Field competitiveness of males of Aedes aegypti (L.) heterozygous for a translocation. — Mosq. News. 35, 3033.
Seawright, J. A.., Kaiser, P. E., WILLIS, N. L., Dame, D. A.. (1976). Field competitiveness of double translocation heterozygote males of Aedes aegypti (L.). — J. med. Ent. 13, 208211.
Serebrovskii, A. S.. (1940).On the possibility of a new method for the control of insect pests.—Zool. Zh. 19, 618–630, [in Russian]. [English translation pp. 123137 in Doyle, E., Freeman, S. M.. (Eds) (1969). Sterile-male technique for eradication or control of harmful insects. IAEA publication STI/PUB/224, Vienna, 42 pp.]
Sokal, R. R., Rohlf, F. J.. (1969). Biometry. — 776 pp.San Francisco, Freeman.
Southwood, T. R. E.., Murdie, G.., Yasuno, M.., Tonn, R. J., Reader, P. M.. (1972). Studies on the life budget of Aedes aegypti in Wat Samphaya, Bangkok, Thailand. — Bull. Wld Hlth Org. 46, 211226.
Trpis, M., Hausermann, W.. (1975). Demonstration, of differential domesticity of Aedes aegypti (L.) (Diptera, Culicidae) in Africa by mark-release-recapture. — Bull. ent. Res. 65, 199208.
Uppal, D. K., Curtis, C. F., Rai, K. S.. (1974). A double translocation heterozygote in Aedes aegypti. — J. communicable Dis. 6, 98101.

Field trials of double translocation heterozygote males for genetic control of Aedes aegypti (L.) (Diptera: Culicidae)

  • J. L. Petersen (a1), L. P. Lounibos (a1) and Nancy Lorimer (a1)


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