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Effect of neutraceutical supplementation on the growth performance and antioxidant activity in liver and plasma of weaned piglets

  • J.H. Guy (a1), S. Arkle (a1), D. Mantle (a2), C.J. Seal (a1), P.J. Blanchard (a3) and P. Toplis (a4)...

Abstract

Post–Weaning Multisystemic Wasting Syndrome (PMWS) can result in mortality levels of up to 80% in weaned piglets, and Porcine Circovirus type 2 (PCV2) has been identified as one of the primary causative agents. Neutraceutical products, based on plant and herbal extracts and containing high levels of natural antioxidants may be beneficial in reducing stress on the piglets’ immune system by elevating blood antioxidant levels, and assisting with the piglets defence against PMWS. The aim of this experiment was to assess the effect of supplementation with neutraceutical products on the growth performance and antioxidant activity in liver and plasma of piglets. It was undertaken on a farm positive for PCV2, but where pigs were not showing clinical signs of PMWS. Groups of newly weaned pigs were offered one of three diets ad libitum for a period of 26 days, standard creep and starter/link control rations, or one of two experimental rations (including Neutraceutical–mix, N, or Lycopene, L), chosen for their potential to boost antioxidant activity. Growth performance and feed intake were monitored, and samples of blood and liver collected at slaughter (54 days of age) and analysed for antioxidant activity. Although L pigs ate significantly less feed during the creep period (P<0.05), there were relatively few performance differences between treatments. However total antioxidant activity in liver samples was significantly higher for the N treatment (P<0.001) and activity of plasma superoxide dismutase was significantly higher in the L group. In conclusion, growth performance of weaned piglets following the addition of Neutraceutical supplements was similar to control groups, and there were significant increases in antioxidant activity of these animals. On the basis that increased levels of circulating blood antioxidants reduce stress on the piglets’ immune system, the results of the current study suggest that these supplements may be of benefit to piglets under immune stress, such as in clinical cases of PMWS.

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Allan, G.M, McNeilly, F., McNair, I., O’Connor, M., Meehan, B, Gilpin, D., Ellis, J., Townsend, H., Lasagna, C., Boriosi, G. and Krakowka, S. 2001. Neonatal vaccination for mycoplasma hyopneumoniae and Postweaning multisystemic wasting syndrome: A field trial. The Pig Journal 48: 3441.
Brice, R.D. (2003) Management systems to control and minimise effects caused by Post–Weaning Multi Systemic Wasting Syndrome and Porcine Dermatitis and Nephropathy Syndrome. Proceedings of the British Society of Animal Science, Annual Meeting, April 2003, York, p224.
Brierley, H. Stewart, A. H. Mackenzie, A.M. Blanchard, P.J. Tucker, L. and Toplis, P. (2003). The effect of lycopene and a neutraceutical mix on the performance and immune function of weaned pigs. Proceedings of the British Society of Animal Science, Annual Meeting, April 2003, York, p89.
Cohen, G. Dembiec, D. Marcus, J. (1970). Measurement of catalase activity in tissue extracts. Analytical Biochemistry 34:3038.
Done, S.H., Bailey, M., Gresham, A.C.J., White, M.E.C., Potter, R.A., Chennells, D. and Thompson, J. 2002. Postweaning multisystemic wasting syndrome (PMWS): The current European situation. The Pig Journal 49: 215232.
Esworthy, R. Aranda, S.R. Martin, M.G. Doroshow, J.H. Binder, S.W. and Chu, F.F. (2001). Mice with combined disruption of Gpx1 and Gpx2 genes have colitis. The American Journal of Gastroenterology Liver Physiology 281: 848855.
McCord, J.M. and Fridovich, I. (1969). Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). Journal of Biological Chemistry 224: 60496055.
Prior, R.L. and Cao, G. (1999). In vivo antioxidant capacity: comparison of different analytical methods. Free Radical Biology and Medicine 27: 11731181.
Re, R. and Proteggente, A. (1998). Antioxdant activity applying an improved ABTS radical cation decolourization assay. Free radical Biology and Medicine 26: 12311237.
Segales, J. and Domingo, M. 2003. Clinical presentation, epidemiological findings, diagnosis, immunity, prevention and control of postweaning multisystemic wasting syndrome (PMWS). Proceedings of the British Society of Animal Science, Annual Meeting, April 2003, York, p223.
Surai, P.F. (2002). Natural Antioxidants in Avian Nutrition and Reproduction First edition Nottingham University Press, Nottingham, UK
Wheeler, C.R. Salzman, J.A. and Elsayed, N.M. (1990). Automated assays for superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activity. Analytical Biochemistry 184: 193199.

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Effect of neutraceutical supplementation on the growth performance and antioxidant activity in liver and plasma of weaned piglets

  • J.H. Guy (a1), S. Arkle (a1), D. Mantle (a2), C.J. Seal (a1), P.J. Blanchard (a3) and P. Toplis (a4)...

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