Skip to main content Accessibility help

Tea consumption and risk of diabetes in the Chinese population: a multi-centre, cross-sectional study

  • Yaling Chen (a1), Wei Li (a1), Shanhu Qiu (a1), Carvalho Vladmir (a1), Xiaohan Xu (a1), Xinling Wang (a2), Xin Nian (a3), Qingyun Chen (a4), Qing Wang (a5), Ping Tu (a6), Lihui Zhang (a7), Sunjie Yan (a8), Kaili Li (a9), Juan Chen (a1), Hang Wu (a1), Xuyi Wang (a1), Xiaohang Wang (a1), Jingbao Liu (a1), Min Cai (a1), Zhiyao Wang (a10), Bei Wang (a11) and Zilin Sun (a1)...


The aim of the present study was to explore the influence of tea consumption on diabetes mellitus in the Chinese population. This multi-centre, cross-sectional study was conducted in eight sites from south, east, north, west and middle regions in China by enrolling 12 017 subjects aged 20–70 years. Socio-demographic and general information was collected by a standardised questionnaire. A standard procedure was used to measure anthropometric characteristics and to obtain blood samples. The diagnosis of diabetes was determined using a standard 75-g oral glucose tolerance test. In the final analysis, 10 825 participants were included and multiple logistic models and interaction effect analysis were applied for assessing the association between tea drinking with diabetes. Compared with non-tea drinkers, the multivariable-adjusted OR for newly diagnosed diabetes were 0·80 (95 % CI 0·67, 0·97), 0·88 (95 % CI 0·71, 1·09) and 0·86 (95 % CI 0·67, 1·11) for daily tea drinkers, occasional tea drinkers and seldom tea drinkers, respectively. Furthermore, drinking tea daily was related to decreased risk of diabetes in females by 32 %, elderly (>45 years) by 24 % and obese (BMI > 30 kg/m2) by 34 %. Moreover, drinking dark tea was associated with reduced risk of diabetes by 45 % (OR 0·55; 95 % CI 0·42, 0·72; P < 0·01). The results imply that drinking tea daily was negatively related to risk of diabetes in female, elderly and obese people. In addition, drinking dark tea was associated with decreased risk of type 2 diabetes mellitus.


Corresponding author

*Corresponding author: Zilin Sun, email


Hide All
1. Wang, L, Gao, P, Zhang, M, et al. (2017) Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013. JAMA 317, 2515.
2. Farag, YM & Gaballa, MR (2011) Diabesity: an overview of a rising epidemic. Nephrology, dialysis, transplantation: official publication of the European dialysis and transplant association. Eur Renal Assoc 26, 2835.
3. Kolb, H & Martin, S (2017) Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes. BMC Med 15, 131.
4. Pan, XR, Li, GW, Hu, YH, et al. (1997) Effect of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. Diab Care 20, 537.
5. Golozar, A, Khademi, H, Kamangar, F, et al. (2011) Diabetes mellitus and its correlates in an Iranian adult population. PLoS ONE 6, e26725.
6. Yajima, H (2014) Prevention of diet-induced obesity by dietary polyphenols derived from Nelumbo nucifera and black tea. Polyphenols Hum Health Dis 15, 135142.
7. Chan, EWC, Soh, EY, Pei, PT, et al. (2011) Antioxidant and antibacterial properties of green, black, and herbal teas of Camellia sinensis . Pharmacogn Res 3, 266272.
8. Sanlier, N, Gokcen, BB & Altug, M (2018) Tea consumption and disease correlations. Trends Food Sci Technol 78, 95106.
9. Fu, QY, Li, QS, Lin, XM, et al. (2017) Antidiabetic effects of tea. Molecules 22, 849.
10. Gondoin, A, Grussu, D, Stewart, D, et al. (2010) White and green tea polyphenols inhibit pancreatic lipase in vitro . Food Res Int 43, 15371544.
11. Mao, JT (2013) Chapter 3. White tea: the plants, processing, manufacturing, and potential health benefits. In Tea in Health and Disease Prevention, pp. 3340 [VR Preedy, editor]. London: Academic Press.
12. Grosso, G, Stepaniak, U, Micek, A, et al. (2015) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study. Eur J Nutr 54, 11291137.
13. Odegaard, AO, Pereira, MA, Koh, WP, et al. (2008) Coffee, tea, and incident type 2 diabetes: the Singapore Chinese health study. Am J Clin Nutr 88, 979985.
14. Oba, S, Nagata, C, Nakamura, K, et al. (2010) Consumption of coffee, green tea, oolong tea, black tea, chocolate snacks and the caffeine content in relation to risk of diabetes in Japanese men and women. Br J Nutr 103, 453459.
15. Siddiqui, FJ, Avan, BI, Mahmud, S, et al. (2015) Uncontrolled diabetes mellitus: prevalence and risk factors among people with type 2 diabetes mellitus in an Urban District of Karachi, Pakistan. Diab Res Clin Prac 107, 148156.
16. Li, W, Xie, B, Qiu, S, et al. (2018) Non-lab and semi-lab algorithms for screening undiagnosed diabetes: a cross-sectional study. EBioMed 35, 307316.
17. Drouin, P, Blickle, JF & Charbonnel, B (1999) Diagnosis and classification of diabetes mellitus: the new criteria. Diab Metabol 25, 7283.
18. Liu, X, Xu, W, Cai, H, et al. (2018) Green tea consumption and risk of type 2 diabetes in Chinese adults: the Shanghai Women’s Health Study and the Shanghai Men’s Health Study. Int J Epidemiol 47, 18871896.
19. Hayashino, Y, Fukuhara, S, Okamura, T, et al. (2011) High oolong tea consumption predicts future risk of diabetes among Japanese male workers: a prospective cohort study. Diab Med 28, 805810.
20. Deng, YT, Lin-Shiau, SY, Shyur, LF, et al. (2015) Pu-erh tea polysaccharides decrease blood sugar by inhibition of α-glucosidase activity in vitro and in mice. Food Func 6, 15391546.
21. Striegel, L, Kang, B, Pilkenton, SJ, et al. (2015) Effect of black tea and black tea pomace polyphenols on α-glucosidase and α-amylase inhibition, relevant to type 2 diabetes prevention. Front Nutr 2, 3
22. Yao, Z, Gu, Y, Zhang, Q, et al. (2019) Estimated daily quercetin intake and association with the prevalence of type 2 diabetes mellitus in Chinese adults. Eur J Nutr 58, 819830.
23. Yang, W-S, Wang, W-Y, Fan, W-Y, et al. (2013) Tea consumption and risk of type 2 diabetes: a dose–response meta-analysis of cohort studies. Br J Nutr 111, 13291339.
24. Jing, Y, Han, G, Hu, Y, et al. (2009) Tea consumption and risk of type 2 diabetes: a meta-analysis of cohort studies. J General Internal Med 24, 557562.
25. Montgomery, MP, Kamel, F, Saldana, TM, et al. (2008) Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993–2003. Am J Epidemiol 167, 12351246.
26. Han, K, Hwang, E & Park, J (2016) Excessive consumption of green tea as a risk factor for periodontal disease among Korean adults. Nutrients 8, 408.
27. Son, HK, Kim, SA & Kang, JH, et al. (2010) Strong associations between low-dose organochlorine pesticides and type 2 diabetes in Korea. Environ Int 36, 410414.
28. Kongpichitchoke, T, Chiu, MT, Huang, TC, et al. (2016) Gallic acid content in Taiwanese teas at different degrees of fermentation and its antioxidant activity by inhibiting PKCδ activation: in vitro and in silico studies. Molecules 21, 1346.
29. Chen, H, Qu, Z, Fu, L, et al. (2010) Physicochemical properties and antioxidant capacity of 3 polysaccharides from green tea, oolong tea, and black tea. J Food Sci 74, C469C474.
30. Zheng, XX, Xu, YL, Li, SH, et al. (2013) Effects of green tea catechins with or without caffeine on glycemic control in adults: a meta-analysis of randomized controlled trials. Am J Clin Nutr 97, 750762.
31. Bhupathiraju, SN, Pan, A, Malik, VS, et al. (2013) Caffeinated and caffeine-free beverages and risk of type 2 diabetes. Am J Clin Nutr 97, 155166.
32. Akter, S, Goto, A & Mizoue, T (2017) Smoking and the risk of type 2 diabetes in Japan: a systematic review and meta-analysis. J Epidemiol 27, 553561.
33. Greenberg, JA, Axen, KV, Schnoll, R, et al. (2005) Coffee, tea and diabetes: the role of weight loss and caffeine. Int J Obes 29, 1121.
34. O’Connor, L, Imamura, F, Lentjes, MAH, et al. (2015) Prospective associations and population impact of sweet beverage intake and type 2 diabetes, and effects of substitutions with alternative beverages. Diabetologia 58, 14741483.
35. Wu, LY, Juan, CC, Ho, LT, et al. (2004) Effect of green tea supplementation on insulin sensitivity in Sprague–Dawley rats. J Agric Food Chem 52, 643648.
36. Mahmoud, F, Haines, D, Al-Ozairi, E, et al. (2016) Effect of black tea consumption on intracellular cytokines, regulatory T cells and metabolic biomarkers in type 2 diabetes patients. Phytother Res 30, 454462.
37. Ãz, H, Luna, C & Estévez, M (2016) Redox chemistry of the molecular interactions between tea catechins and human serum proteins under simulated hyperglycemic conditions. Food Func 7, 13901400.
38. Neyestani, TR, Shariatzade, N, Kalayi, A, et al. (2010) Regular daily intake of black tea improves oxidative stress biomarkers and decreases serum C-reactive protein levels in type 2 diabetic patients. Ann Nutr Metabol 57, 4049.


Tea consumption and risk of diabetes in the Chinese population: a multi-centre, cross-sectional study

  • Yaling Chen (a1), Wei Li (a1), Shanhu Qiu (a1), Carvalho Vladmir (a1), Xiaohan Xu (a1), Xinling Wang (a2), Xin Nian (a3), Qingyun Chen (a4), Qing Wang (a5), Ping Tu (a6), Lihui Zhang (a7), Sunjie Yan (a8), Kaili Li (a9), Juan Chen (a1), Hang Wu (a1), Xuyi Wang (a1), Xiaohang Wang (a1), Jingbao Liu (a1), Min Cai (a1), Zhiyao Wang (a10), Bei Wang (a11) and Zilin Sun (a1)...


Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed