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Risk of iron overload in carriers of genetic mutations associated with hereditary haemochromatosis: UK Food Standards Agency workshop

Published online by Cambridge University Press:  08 March 2007

Mamta Singh ,
Margaret Ashwell ,
Peter Sanderson ,
Janet Cade ,
Jennifer Moreton ,
Susan Fairweather-Tait ,
Mark Roe ,
Joannes J. M. Marx ,
Mark Worwood  and
James D. Cook
Mamta Singh*
Affiliation:
Food Standards Agency, Aviation House, 125 Kingsway, London WC2B 6NH, UK
Margaret Ashwell
Affiliation:
Ashwell Associates, Ashwell Street, Ashwell, Hertfordshire SG7 5PZ, UK
Peter Sanderson
Affiliation:
Food Standards Agency, Aviation House, 125 Kingsway, London WC2B 6NH, UK
Janet Cade
Affiliation:
Leeds University, Centre for Epidemiology and Biostatistics, 30–32 Hyde Terrace, Leeds LS2 9JT, UK
Jennifer Moreton
Affiliation:
Leeds University, Centre for Epidemiology and Biostatistics, 30–32 Hyde Terrace, Leeds LS2 9JT, UK
Susan Fairweather-Tait
Affiliation:
Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
Mark Roe
Affiliation:
Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK
Joannes J. M. Marx
Affiliation:
Eijkman-Winkler Institute for Microbiology, Infections Diseases and Inflammation, University Medical Centre, Utrecht, the Netherlands
Mark Worwood
Affiliation:
University of Wales College of Medicine, Cardiff CF14 4XN, UK
James D. Cook
Affiliation:
University of Kansas Medical Centre, Kansas City, KS 66160, USA
*
*Corresponding author: Ms Mamta Singh, fax +44 20 7276 8906, email mamta.singh@foodstandards.gsi.gov.uk
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Abstract

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The UK Food Standards Agency convened a group of expert scientists to review current research investigating diet and carriers of genetic mutations associated with hereditary haemochromatosis. The workshop concluded that individuals who are heterozygous for the C282Y mutation of the HFE gene do not appear to respond abnormally to dietary Fe and therefore do not need to change their diet to prevent accumulation of body Fe.

Keywords

Iron overloadHereditary haemochromatosisFood Standards Agency workshops
Type
Workshop Report
Information
British Journal of Nutrition , Volume 96 , Issue 4 , October 2006 , pp. 770 - 773
Copyright
Copyright © The Nutrition Society 2006

References

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