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Plasma retinol and tocopherol levels in relation to demographic, lifestyle and nutritional factors of plant origin in Greece

Published online by Cambridge University Press:  09 March 2007

A. Papas
Affiliation:
Eastman Chemical Company, Kingsport, TN, USA
M. Stacewicz-Sapuntzakis
Affiliation:
Department of Human Nutrition and Dietetics, College of Health and Human Development Sciences, University of Illinois at Chicago, Chicago, IL, USA
P. Lagiou
Affiliation:
Department of Hygiene and Epidemiology, University of Athens Medical School, 75 M.Asias St. GR-115 27, Goudi, Athens, Greece
C. Bamia
Affiliation:
Department of Hygiene and Epidemiology, University of Athens Medical School, 75 M.Asias St. GR-115 27, Goudi, Athens, Greece
Y. Chloptsios
Affiliation:
Department of Hygiene and Epidemiology, University of Athens Medical School, 75 M.Asias St. GR-115 27, Goudi, Athens, Greece
A. Trichopoulou
Affiliation:
Department of Hygiene and Epidemiology, University of Athens Medical School, 75 M.Asias St. GR-115 27, Goudi, Athens, Greece
Corresponding
E-mail address:
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Abstract

In the context of the Greek segment of the European Prospective Investigation into Cancer and Nutrition (EPIC) we have conducted a cross-sectional study to determine the effect of demographic, lifestyle and nutritional factors of plant origin on retinol, α-tocopherol and γ-tocopherol. Study subjects were a random sample of forty-five men and sixty-eight women, aged 30–82 years, from the Greek EPIC cohort of 27953 volunteers. Analyses were done using linear regression models with the vitamin blood levels as dependent variables, and BMI, the intake of selected food items, total energy intake and a set of demographic factors as independent variables. Women had significantly lower plasma retinol levels (P<0·006) than men. Both α- and γ-tocopherol levels increased by approximately 5 % for every additional 5 years of age. Among dietary factors, intake of non-fruity vegetables was associated with increase, while intake of added lipids other than olive oil with decrease, of plasma retinol levels. BMI was positively associated with plasma γ-tocopherol only, while none of the foods or food groups investigated significantly affected the plasma levels of either of the two tocopherols. These findings need to be confirmed before attempts are made to use them in the context of explanatory mechanistic processes.

Type
Research Article
Copyright
Copyright © The Nutrition Society 2003

References

Blumberg, J & Block, G (1994) The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study in Finland. Nutrition Reviews 52, 242245.CrossRefGoogle ScholarPubMed
Gnardellis, C, Trichopoulou, A, Katsouyanni, K, Polychronopoulos, E, Rimm, EB & Trichopoulos, D (1995) Reproducibility and validity of an extensive semi-quantitative Food Frequency Questionnaire among Greek school teachers. Epidemiology 6, 7477.CrossRefGoogle Scholar
Hallfrisch, J, Muller, DC & Singh, VN (1994) Vitamin A and E intakes and plasma concentrations of retinol, beta-carotene, and alpha-tocopherol in men and women of the Baltimore Longitudinal Study of Aging. American Journal of Clinical Nutrition 60, 176182.CrossRefGoogle Scholar
Ito, Y, Shima, Y, Ochiai, J, Otani, M, Sasaki, R, Suzuki, S, Hamajima, N, Ogawa, H & Aoki, K (1991) Effects of the consumption of cigarettes, alcohol and foods on serum concentrations of carotenoids, retinol and tocopherols in healthy inhabitants living in a rural area of Hokkaido. Nippon Eiseigaku Zasshi 46, 874882.CrossRefGoogle Scholar
Katsouyanni, K, Rimm, EB, Gnardellis, C, Trichopoulos, D, Polychronopoulos, E & Trichopoulou, A (1997) Reproducibility and relative validity of an extensive semi-quantitative Food Frequency Questionnaire using dietary records and chemical markers among Greek school teachers. International Journal of Epidemiology 26, Suppl. 1, 118127.CrossRefGoogle Scholar
Knekt, P, Seppanen, R & Aaran, RK (1988) Determinants of serum alpha-tocopherol in Finnish adults. Preventive Medicine 17, 725735.CrossRefGoogle ScholarPubMed
Lentner, C (editor) (1984) Geigy Scientific Tables, vol. 3 – Physical Chemistry, Composition of Blood, Hematology, Somatometric Data, pp. 126127. Basle, Switzerland: CIBA-GEIGY.Google Scholar
Morinobu, T, Tamai, H, Tanabe, T, Murata, T, Manago, M, Mino, M & Hirahara, F (1994) Plasma alpha-tocopherol, beta-carotene, and retinol levels in the institutionalized elderly individuals and in young adults. International Journal of Vitamin and Nutrition Research 64, 104108.Google ScholarPubMed
National Research Council (1989) Diet and Health: Implications for Reducing Chronic Disease Risk. Washington, DC: National Academy Press.Google Scholar
Nierenberg, DW, Stukel, TA, Baron, JA, Dain, BJ & Greenberg, ER (1989) Determinants of plasma levels of beta-carotene and retinol. Skin Cancer Prevention Study Group. American Journal of Epidemiology 130, 511521.CrossRefGoogle ScholarPubMed
Olmedilla, B, Granado, F, Blanco, I & Rojas-Hidalgo, E (1994) Seasonal and sex-related variations in six serum carotenoids, retinol, and alpha-tocopherol. American Journal of Clinical Nutrition 60, 106110.CrossRefGoogle ScholarPubMed
Papas, A (editor) (1999) Antioxidant Status, Diet, Nutrition, and Health. Boca Raton, FL: CRC Press.Google Scholar
Riboli, E (1992) Nutrition and Cancer: Background and rationale of the European Prospective Investigation into Cancer and Nutrition (EPIC). Annals of Oncology 3, 783791.CrossRefGoogle Scholar
Stacewicz-Sapuntzakis, M, Bowen, PE, Kikendall, JW & Burgess, M (1987) Simultaneous determination of serum retinol and various carotenoids: their distribution in middle-aged men and women. Journal of Micronutrient Analysis 3, 2745.Google Scholar
Trichopoulos, D, Tzonou, A, Katsouyanni, K & Trichopoulou, A (1991) Diet and cancer: The role of case-control studies. Annals of Nutrition and Metabolism 35, Suppl. 1, 8992.CrossRefGoogle ScholarPubMed
Trichopoulou, A (1992) Composition of Greek Foods and Dishes (in Greek and English). Athens, Greece: Athens School of Public Health.Google Scholar
Trichopoulou, A, Lagiou, P & Trichopoulos, D (1994) Traditional Greek diet and coronary heart disease. Journal of Cardiovascular Risk 1, 915.CrossRefGoogle ScholarPubMed
Trichopoulou, A, Vasilopoulou, E & Lagiou, A (1999) Mediterranean diet and coronary heart disease: are antioxidants critical? Nutrition Reviews 57, 253255.Google ScholarPubMed
Virtanen, SM, van't Veer, P, Kok, F, Kardinaal, AF & Aro, A (1996) Predictors of adipose tissue carotenoid and retinol levels in nine countries. The EURAMIC Study. American Journal of Epidemiology 144, 968979.CrossRefGoogle ScholarPubMed
Willett, W (1998) Nutritional Epidemiology, 2nd ed. New York: Oxford University Press.CrossRefGoogle Scholar
Willett, W & Stampfer, MJ (1986) Total energy intake: implications for epidemiologic analyses. American Journal of Epidemiology 124, 1727.CrossRefGoogle ScholarPubMed
Willett, WC (1994) Diet and health: what should we eat? Science 264, 532537.CrossRefGoogle ScholarPubMed
Willett, WC & Trichopoulos, D (1996) Summary of the evidence: Nutrition and cancer. Cancer Causes and Control 7, 178180.CrossRefGoogle ScholarPubMed
World Cancer Research Fund and American Institute for Cancer Prevention (1997) Food, Nutrition and the Prevention of Cancer: a Global Perspective. Washington, DC: World Cancer Research Fund and American Institute for Cancer Prevention.Google Scholar

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