1. Cooke, A (2017) Dietary food-additive phosphate and human health outcomes. Compr Rev Food Sci Food Saf 16, 906–1021.
2. Kienzle, E, Thielen, C & Pessinger, C (1998) Investigations on phosphorus requirements of adult cats. J Nutr 128, 2598s–2600s.
3. Pastoor, FJ, Van’t Klooster, AT, Mathot, JN, et al. (1995) Increasing phosphorus intake reduces urinary concentrations of magnesium and calcium in adult ovariectomized cats fed purified diets. J Nutr 125, 1334–1341.
4. Fettman, MJ, Coble, JM, Hamar, DW, et al. (1992) Effect of dietary phosphoric acid supplementation on acid–base balance and mineral and bone metabolism in adult cats. Am J Vet Res 53, 2125–2135.
5. National Research Council (2006) National Research Council: Nutrient Requirements of Dogs and Cats. Washington, DC: National Academies Press.
6. Dobenecker, B, Webel, A, Reese, S, et al. (2018) Effect of a high phosphorus diet on indicators of renal health in cats. J Feline Med Surg 20, 339–343.
7. Mack, JK, Alexander, LG, Morris, PJ, et al. (2015) Demonstration of uniformity of calcium absorption in adult dogs and cats. J Anim Physiol Anim Nutr (Berl) 99, 801–809.
8. Finco, DR, Barsanti, JA & Brown, SA (1989) Influence of dietary source of phosphorus on fecal and urinary excretion of phosphorus and other minerals by male cats. Am J Vet Res 50, 263–266.
9. Noori, N, Sims, J, Kopple, J, et al. (2010) Organic and inorganic dietary phosphorus and its management in chronic kidney disease. Iran J Kidney Dis 4, 89–100.
10. Dobenecker, B, Schaschl, C, Webel, A, et al. (2018) A comparison of the faecal and renal phosphorus excretion after excessive intake of monophosphate from calcium and potassium monophosphate in adult cats. In Proceedings of the Society of Nutrition Physiology, vol. 27, p. 95. Frankfurt am Main: DLG-Verlag.
11. Isakova, T, Gutierrez, O, Shah, A, et al. (2008) Postprandial mineral metabolism and secondary hyperparathyroidism in early CKD. J Am Soc Nephrol 19, 615–623.
12. Silver, J, Rodriguez, M & Slatopolsky, E (2012) FGF23 and PTH–double agents at the heart of CKD. Nephrol Dial Transplant 27, 1715–1720.
13. Nagode, LA, Chew, DJ & Podell, M (1996) Benefits of calcitriol therapy and serum phosphorus control in dogs and cats with chronic renal failure. Both are essential to prevent of suppress toxic hyperparathyroidism. Vet Clin North Am Small Anim Pract 26, 1293–1330.
14. Tani, Y, Sato, T, Yamanaka-Okumura, H, et al. (2007) Effects of prolonged high phosphorus diet on phosphorus and calcium balance in rats. J Clin Biochem Nutr 40, 221–228.
15. Uribarri, J (2007) Phosphorus metabolism and management in chronic kidney disease: phosphorus homeostasis in normal health and in chronic kidney disease patients with special emphasis on dietary phosphorus intake. Semin Dial 20, 295–301.
16. Kestenbaum, B, Sampson, JN, Rudser, KD, et al. (2005) Serum phosphate levels and mortality risk among people with chronic kidney disease. J Am Soc Nephrol 16, 520–528.
17. Hitchman, AJ, Hasany, SA, Hitchman, A, et al. (1979) Phosphate-induced renal calcification in the rat. Can J Physiol Pharmacol 57, 92–97.
18. Ritskes-Hoitinga, J, Lemmens, AG & Beynen, AC (1989) Nutrition and kidney calcification in rats. Lab Anim 23, 313–318.
19. Gonzalez-Parra, E, Gracia-Iguacel, C, Egido, J, et al. (2012) Phosphorus and nutrition in chronic kidney disease. Int J Nephrol 2012, 597605.
20. Alexander, J, Stockman, J, Atwal, J, et al. (2018) Effects of the long term feeding of diets enriched with inorganic phosphorus on the adult feline kidney and phosphorus metabolism. Br J Nutr .
21. Dobenecker, B & Siedler, S (2017) Knowing the total amount of phosphorus in a diet is not enough – different sources have different effects. In Congress of the European College of Veterinary Internal Medicine – Companion Animals. Malta: European Society of Veterinary Internal Medicine.
22. Berndt, T & Kumar, R (2009) Novel mechanisms in the regulation of phosphorus homeostasis. Physiology 24, 17–25.
23. Moe, SM, Zidehsarai, MP, Chambers, MA, et al. (2011) Vegetarian compared with meat dietary protein source and phosphorus homeostasis in chronic kidney disease. Clin J Am Soc Nephrol 6, 257–264.
24. Moore, LW, Nolte, JV, Gaber, AO, et al. (2015) Association of dietary phosphate and serum phosphorus concentration by levels of kidney function. Am J Clin Nutr 102, 444–453.
25. Karp, HJ, Vaihia, KP, Kärkkäinen, MUM, et al. (2007) Acute effects of different phosphorus sources on calcium and bone metabolism in young women: a whole-foods approach. Calcif Tissue Int 80, 251–258.
26. Hazim, J, Hlais, S, Ghattas, H, et al. (2014) Phosphorus supplement alters postprandial lipemia of healthy male subjects: a pilot cross-over trial. Lipids Health Dis 13, 109.
27. Wetmore, JB, Santos, PW, Mahnken, JD, et al. (2011) Elevated FGF23 levels are associated with impaired calcium-mediated suppression of PTH in ESRD. J Clin Endocrinol Metab 96, E57–E64.
28. Canalejo, R, Canalejo, A, Martinez-Moreno, JM, et al. (2010) FGF23 fails to inhibit uremic parathyroid glands. J Am Soc Nephrol 21, 1125–1135.
29. Siedler, S & Dobenecker, B (2015) Effect of different P sources in high phosphorus diets with balanced Ca/P ratio on serum PTH, P and calcium levels as well as apparent digestibility of these minerals in dogs. Conference of the European Society of Veterinary Internal Medicine, Toulouse.
30. Bjornvad, CR, Nielsen, DH, Armstrong, PJ, et al. (2011) Evaluation of a nine-point body condition scoring system in physically inactive pet cats. Am J Vet Res 72, 433–437.
31. Geddes, R, Finch, N, Elliott, J, et al. (2013) Fibroblast growth factor 23 in feline chronic kidney disease. J Vet Intern Med 27, 234–241.
32. Williams, T, Elliott, J & Syme, H (2012) Calcium and phosphate homeostasis in hyperthyroid cats–associations with development of azotaemia and survival time. J Small Anim Pract 53, 561–571.
33. R Development Core Team (2017) R: A Language and Environment for Statistical Computing. Vienna: R Foundation for Statistical Computing.
34. Bates, D, Mächler, M, Bolker, B et al. (2015) Fitting linear mixed-effects models using lme4. 67, 1–48.
35. Hothorn, T, Bretz, F & Westfall, P (2008) Simultaneous inference in general parametric models. Biom J 50, 346–363.
36. Wickham, H (2009) Ggplot2: Elegant Graphics for Data Analysis, vol. 16. New York: Springer Verlag.
37. Rosol, TJ & Capen, CC (1996) Pathophysiology of calcium, phosphorus, and magnesium metabolism in animals. Vet Clin North Am Small Anim Pract 26, 1155–1184.
38. Kemi, VE, Karkkainen, MU & Lamberg-Allardt, CJ (2006) High phosphorus intakes acutely and negatively affect Ca and bone metabolism in a dose-dependent manner in healthy young females. Br J Nutr 96, 545–552.
39. Kärkkäinen, M & Lamberg-Allardt, C (1996) An acute intake of phosphate increases parathyroid hormone secretion and inhibits bone formation in young women. J Bone Miner Res 11, 1905–1912.
40. McDonald, JL Jr, Stookey, GK & Muhler, JC (1970) Radiophosphorus metabolism of different phosphate compounds in experimental animals. J Dent Res 49, 1042–1048.
41. Geddes, RF, Biourge, V, Chang, Y, et al. (2016) The effect of moderate dietary protein and phosphate restriction on calcium-phosphate homeostasis in healthy older cats. J Vet Intern Med 30, 1690–1702.
42. Finch, NC, Geddes, RF, Syme, HM, et al. (2013) Fibroblast growth factor 23 (FGF-23) concentrations in cats with early nonazotemic chronic kidney disease (CKD) and in healthy geriatric cats. J Vet Intern Med 27, 227–233.
43. Geddes, RF, Elliott, J & Syme, HM (2013) The effect of feeding a renal diet on plasma fibroblast growth factor 23 concentrations in cats with stable azotemic chronic kidney disease. J Vet Intern Med 27, 1354–1361.
44. Geddes, RF, Elliott, J & Syme, HM (2015) Relationship between plasma fibroblast growth factor-23 concentration and survival time in cats with chronic kidney disease. J Vet Intern Med 29, 1494–1501.
45. Nishida, Y, Taketani, Y, Yamanaka-Okumura, H, et al. (2006) Acute effect of oral phosphate loading on serum fibroblast growth factor 23 levels in healthy men. Kidney Int 70, 2141–2147.
46. Takasugi, S, Akutsu, M & Nagata, M (2014) Oral phosphorus supplementation secondarily increases circulating fibroblast growth factor 23 levels at least partially via stimulation of parathyroid hormone secretion. J Nutr Sci Vitaminol 60, 140–144.
47. Calvo, MS, Moshfegh, AJ & Tucker, KL (2014) Assessing the health impact of phosphorus in the food supply: issues and considerations. Adv Nutr 5, 104–113.
48. Fingerhut, M, Ruf, F & Lang, K (1966) Zur Frage der Resorption von Polyphosphaten (On the question of the absorption of polyphosphates). Zeitschrift für Ernährungswissenschaft 6, 228–241.
49. Pastoor, FJ, Opitz, R, Van’t Klooster, AT, et al. (1994) Dietary calcium chloride vs. calcium carbonate reduces urinary pH and phosphorus concentration, improves bone mineralization and depresses kidney calcium level in cats. J Nutr 124, 2212–2222.
50. Pastoor, FJ, Van’t Klooster, AT, Mathot, JN, et al. (1994) Increasing calcium intakes lower urinary concentrations of phosphorus and magnesium in adult ovariectomized cats. J Nutr 124, 299–304.
51. Kienzle, E, Pessinger, C & Thielen, C (1998) Phosphorus requirements of adult cats. J Anim Physiol Anim Nutr 80, 90–100.
52. Pastoor, FJ, Van’t Klooster, AT, Opitz, R, et al. (1995) Effect of dietary magnesium level on urinary and faecal excretion of calcium, magnesium and phosphorus in adult, ovariectomized cats. Br J Nutr 74, 77–84.
53. Prola, L, Dobenecker, B, Mussa, PP, et al. (2010) Influence of cellulose fibre length on faecal quality, mineral excretion and nutrient digestibility in cat. J Anim Physiol Anim Nutr 94, 362–367.
54. Ching, SV, Fettman, MJ, Hamar, DW, et al. (1989) The effect of chronic dietary acidification using ammonium chloride on acid–base and mineral metabolism in the adult cat. J Nutr 119, 902–915.
55. Kienzle, E, Schuknecht, A & Meyer, H (1991) Influence of food composition on the urine pH in cats. J Nutr 121, S87–S88.
56. Coradini, M, Rand, JS, Filippich, LJ, et al. (2015) Associations between meal size, gastric emptying and post-prandial plasma glucose, insulin and lactate concentrations in meal-fed cats. J Anim Physiol Anim Nutr 99, 757–766.
57. Vist, GE & Maughan, RJ (1995) The effect of osmolality and carbohydrate content on the rate of gastric emptying of liquids in man. J Physiol 486, 523–531.
58. Marks, J, Lee, GJ, Nadaraja, SP, et al. (2015) Experimental and regional variations in Na+-dependent and Na+-independent phosphate transport along the rat small intestine and colon. Physiol Rep 3, e12281.
59. Reinhold, JG, Faradji, B, Abadi, P, et al. (1976) Decreased absorption of calcium, magnesium, zinc and phosphorus by humans due to increased fiber and phosphorus consumption as wheat bread. J Nutr 106, 493–503.
60. Hernández, A, Concepción, MT, Rodríguez, M, et al. (1996) High phosphorus diet increases preproPTH mRNA independent of calcium and calcitriol in normal rats. Kidney Int 50, 1872–1878.
61. Jeremias, JT, Nogueira, SP, Brunetto, MA, et al. (2013) Predictive formulas for food base excess and urine pH estimations of cats. Anim Feed Sci Technol 182, 82–92.