Skip to main content Accessibility help
×
Home

Alcohol and its acute effects on resting metabolic rate and diet-induced thermogenesis

  • Jan A. Weststrate (a1), Ingrid Wunnink (a1), Paul Deurenberg (a1) and Joseph G. A. J. Hautvast (a1)

Abstract

The impact of alcohol (ethanol) on resting energy expenditure of male non-obese volunteers was determined in two studies. In the first study the thermic effect of alcohol on resting metabolic rate (RMR) was assessed in ten male non-obese volunteers. In the second study the impact of alcohol on diet-induced thermogenesis (DIT) was determined in twelve male non-obese volunteers. Energy expenditure was measured with a ventilated-hood system. RMR was measured for 60 min with the subjects in a fasting state. In the first study subjects received in random order 20 g alcohol in concentrations of 75, 180 and 300 ml/I water respectively. After measurement of the RMR the thermic effect of alcohol was measured for 90 min. In the second study volunteers received in random order and in duplicate either a meal of food (2 MJ) plus an alcoholic aperitif (20 g alcohol in a 180 ml/1 solution) or an isoenergetic meal of food alone (2.55 MJ) plus a placebo aperitif containing no alcohol. DIT was measured for 240 min. Alcohol induced a significant thermic effect, which varied between 0.22 and 0.30 kJ/min. No systematic difference in DIT was observed among the different concentrations. DIT was not significantly affected by the ingestion of alcohol. Total DIT was 219 (SE 14) kJ for the alcohol treatment and 185 (SE 20) kJ for the control treatment. The results do not support the suggestion that alcohol is less efficiently used as an energy source in comparison with, for example, fats and carbohydrates.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Alcohol and its acute effects on resting metabolic rate and diet-induced thermogenesis
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Alcohol and its acute effects on resting metabolic rate and diet-induced thermogenesis
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Alcohol and its acute effects on resting metabolic rate and diet-induced thermogenesis
      Available formats
      ×

Copyright

References

Hide All
Atwater, W. D. & Benedict, F. G. (1902). An experimental inquiry regarding the nutritive value of alcohol. Memoirs of the National Academy of Sciences 8, 235397.
Barnes, E. W., Cooke, N. J., King, A. J. & Passmore, R. (1965). Observations on the metabolism of alcohol in man. British Journal of Nutrition 19, 485489.
Bebb, H. T., Houser, H. B., Witschi, J. C., Littell, A. S. & Fuller, R. K. (1971). Calorie and nutrient contribution of alcoholic beverages to the usual diets of 155 adults. American Journal of Clinical Nutrition 24, 10421052.
Bouman, W. C. & Rand, M. J. (1980). Textbook of Pharmacology, 2nd ed. Oxford: Blackwell Scientific Publications.
Camargo, C. A., Vranizan, K. M., Dreon, D. M., Frey-Hewitt, B. & Wood, P. D. (1987). Alcohol calorie intake, and adiposity in overweight men. Journal of the American College of Nutrition 6, 271278.
Crouse, J. R. & Grundy, S. M. (1984). Effects of alcohol on plasma lipoproteins and cholesterol and triglyceride metabolism in man. Journal of Lipid Research 25, 486496.
Den Besten, C., Vansant, G., Weststrate, J. A. & Deurenberg, P. (1988). Resting metabolic rate and diet-induced thermogenesis in abdominal and gluteal-femoral obese women before and after weight reduction. American Journal of Clinical Nutrition 47, 840847.
Dipadova, C., Worner, T. M., Julkunen, R. J. K. & Lieber, C. S. (1987). Effects of fasting and chronic alcohol consumption on the first-pass metabolism of ethanol. Gastroenterology 92, 11691173.
Fisher, M. & Gordon, T. (1985). The relation of drinking and smoking habits to diet: The Lipid Research Clinics Prevalence Study. American Journal of Clinical Nutrition 41, 623630.
Flatt, J. P. (1978). Biochemistry of energy expenditure. In Recent Advances in Obesity Research, vol. 2, pp. 211228 [Bray, G., editor]. London: John Libbey.
Gruchow, H. W., Sobocinski, K. A., Barboriak, J. J. & Scheller, J. G. (1985). Alcohol consumption, nutrient intake and relative body weight among US adults. American Journal of Clinical Nutrition 42, 289295.
Hillers, V. N. & Massey, L. K. (1985). Interrelationships of moderate and high alcohol consumption with diet and health status. American Journal of Clinical Nutrition 41, 356362.
Jéquier, E. (1984). Thermogenesis induced by nutrient administration in man. Infusionstherapie 4, 184188.
Jéquier, E. (1985). Direct and indirect calorimetry. In Substrate and Energy Metabolism, pp. 8292 [Garrow, J. S. and Halliday, D., editors]. London: John Libbey.
Jones, B. R., Barett-Connor, E., Criqui, M. H. & Holdbrook, M. J. (1982). A community study of calorie and nutrient intake in drinkers and nondrinkers of alcohol. American Journal of Clinical Nutrition 35, 135139.
Kinney, J. M. [editor] (1980). The application of indirect calorimetry to clinical studies. In Assessment of Energy Metabolism in Health and Disease, pp. 4248. Columbus: Ross Laboratories.
Klatsky, A. L. (1979). Effects of alcohol on the cardiovascular system. In Fermented Food Beverages in Nutrition, pp. 317336 [Castineau, G. F., Darby, W. L. and Turner, T. B., editors]. New York: Academic Press.
Lieber, C. S. (1982). Medical Disorders of Alcoholism: Pathogenesis and Treatment. Philadelphia: Saunders.
McDonald, J. T. & Margen, S. (1976). Wine versus ethanol in human nutrition. I, Nitrogen and calorie balance. American Journal of Clinical Nutrition 29, 10931103.
Mercy, E. (1980). Alcoholic liver disease: roles of alcohol and malnutrition. American Journal of Clinical Nutrition 33, 27092718.
Ministerie van Welzijn, Volksgezondheid en Cultuur & Ministerie van Landbouw en Visserij (1988). Wat eet Nederland. Resultaten van de voedselconsumptiepeiling 1987–1988. Rijswijk: Staatsdrukkerij.
Perman, E. S. (1962). Increase in oxygen uptake after small ethanol doses in man. Acta Physiologica Scandinavica 55, 207209.
Pirola, R. D. & Lieber, C. S. (1972). Energy cost of the metabolism of drugs, including ethanol. Pharmacology 7, 185196.
Ravussin, E., Lillioja, S., Anderson, T. E., Christin, L. & Bogardus, C. (1986). Determinants of 24-hour energy expenditure in man. Journal of Clinical Investigation 78, 15681578.
Rosenberg, K. & Durnin, J. V. G. A. (1978). The effect of alcohol on resting metabolic rate. British Journal of Nutrition 40, 293298.
Sims, E. A. H. & Danforth, E. (1987). Expenditure and storage of energy in man. Journal of Clinical Investigation 79, 10191025.
Siri, W. E. (1956). The gross composition of the body. Advances in Biological and Medical Physics 4, 239280.
Spring, J. A. & Buss, D. H. (1977). Three centuries of alcohol in the British diet. Nature 270, 567572.
Stock, M. J. & Stuart, J. A. (1974). Thermic effects of ethanol in the rat and man. Nutrition and Metabolism 17, 297305.
Sulkunen, P. (1976). Production, consumption and recent changes on consumption of alcoholic beverages. British Journal of Addiction 71, 115122.
Weststrate, J. A., Weys, P. J. M., Poortvliet, E. J., Deurenberg, P. & Hautvast, J. G. A. J. (1989). Diurnal variation in postabsorptive resting metabolic rate and diet-induced thermogenesis. American Journal of Clinical Nutrition 50, 908915.
World Health Organization (1980). Problems Related to Alcohol Consumption. Technical Report Series no. 650. Geneva: WHO.

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed