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Long-term changes of synaptic transmission: A topic of long-term interest
Published online by Cambridge University Press: 19 May 2011
Abstract
Long-term modifications of synaptic efficacy at excitatory synapses are considered as a putative cellular substrate for learning and memory processes. Cerebellar long-term depression (LTD) occurring at parallel fibers (PF)-Purkinje neurons (PN) synapses is thought to repre-sent a cellular model of motor learning. Crépel et al. and Linden describe this phenomenon by utilizing different tissue preparations. [CRÉPEL et al., LINDEN]
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