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Anatomical structure alone cannot predict function
Published online by Cambridge University Press: 30 August 2019
Abstract
The central hypothesis of Braitenberg et al.'s target article – that tidal waves of parallel fiber excitation precisely activate Purkinje cell spiking – is hard to reconcile with recent neurophysiological and modeling data. The assumed pattern of mossy fiber input seems unrealistic, inhibition is likely to interfere with the proposed excitatory responses, and moreover, computer simulations show that the Purkinje cell is a poor coincidence detector.
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- 1997 Cambridge University Press
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