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Preventing a paradigm shift: A plea for the computational genome

Published online by Cambridge University Press:  24 October 2012

Carmine Garzillo
Affiliation:
Dipartimento di Scienze mediche preventive, Università di Napoli Federico II, 80138 Naples, Italy. carmine.garzillo@unina.it
Giuseppe Trautteur
Affiliation:
Dipartimento di Scienze fisiche, Università di Napoli Federico II, 80138 Naples, Italy. trau@na.infn.it

Abstract

Against the opinion that DNA as program is not sufficiently explanatory, we maintain that the cellular machinery is entirely computational, and we identify the crucial notion of the interpreter that expresses the gene with the minimal gene set. Epigenetics research does not so much need paradigm shifts as the unraveling of an exceedingly complex computational machine.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2012 

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