Manila clams, Tapes philippinarum (Adams and Reeve) are cultivated beneath plastic netting, to protect them from excessive predation, and harvested after approximately two years. Both the on-growing and harvesting process have the potential to alter benthic communities. In order to study these effects, we surveyed a clam lay and uncultivated areas at a site of commercial clam cultivation in south-east England. Surveys were undertaken at the end of the growing stage, immediately after harvesting by suction dredge and seven months later. Infaunal abundance was greatest within a net covered clam lay than in proximate and distant control areas, but the total number of species encountered was similar in all areas (20–22). These differences were not attributable to variation in sediment structure or environmental variables between the areas sampled. Tube-building polychaetes, such as Lanice conchilega and Euclymene lumbricoides, were particularly abundant within the cultivated area as was the errant polychaete, Syllis gracilis. Harvesting by suction dredge altered sediment composition by removing the larger sand fractions down to the underlying clay substratum, consequently there was a large reduction in the density of all individuals and the total number of species. Seven months later, no significant difference was found between the infaunal community in the harvested clam lay or either of the control areas and sedimentation had nearly restored the sediment structure. These observations indicate that the practice of clam cultivation does not have long-term effects on the environment or benthic community at this site.