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Constrained sentence production in probable Alzheimer disease

Published online by Cambridge University Press:  17 May 2004

LORI J. P. ALTMANN
LORI J. P. ALTMANN
Affiliation:
University of Florida
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Abstract

This study examines the speech of older adults with and without probable Alzheimer disease (PAD) when they produce sentences that include a verb and two nouns provided by the experimenter. Compared to healthy controls, individuals with mild PAD produced fewer correct responses as well as anomalous proportions of active and passive sentences. Responses were particularly impaired when canonical sentence structures had to be suppressed and unusual sentence structures generated. The sentence production accuracy of individuals with PAD correlated strongly with performance on a picture-naming task. The findings support a theory in which the ability to fully activate semantic representations is impaired in PAD, resulting in proportional impairments on single-word and sentence production tasks.

Type
Articles
Information
Applied Psycholinguistics , Volume 25 , Issue 2 , April 2004 , pp. 145 - 173
Copyright
© 2004 Cambridge University Press

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References

Albert M., & Millburg W. 1989 Semantic processing in patients with Alzheimer's disease. Brain and Language, 37, 163– 171.Google Scholar
Almor A., Kempler D., MacDonald M. C., & Andersen E. S. 1997 Discourse comprehension in Alzheimer's disease. Brain and Language, 60, 185– 188.Google Scholar
Almor A., Kempler D., MacDonald M. C., Andersen E. S., & Tyler L. K. 1999 Why do Alzheimer patients have difficulty with pronouns? Working memory, semantics, and reference in comprehension and production in Alzheimer's disease. Brain and Language, 67, 202– 227.Google Scholar
Almor A., MacDonald M. C., Kempler D., Andersen E. S., & Tyler L. K. 2001 Comprehension of long distance number agreement in probable Alzheimer's disease. Language and Cognitive Processes, 16, 35– 63.Google Scholar
Altmann G. T. M. 1999 Thematic role assignment in context. Journal of Memory and Language, 41, 124– 145.Google Scholar
Altmann L. J. P., & Kemper S. 2004a Age differences in sensitivity to animacy and order of activation in sentence production. Manuscript submitted for publication.
Altmann L. J. P., & Kemper S. 2004b Dedifferentiation of working memory and language proficiency in older adults. Manuscript submitted for publication.
Altmann L. J. P., Kempler D., & Andersen E. S. 2001 Speech production in Alzheimer's disease: Reevaluating morphosyntactic preservation. Journal of Speech, Language & Hearing Research, 44, 1069– 1082.Google Scholar
Bates E., Marchman V., Harris C., Wulfeck B., & Kritchevsky M. 1995 Production of complex syntax in normal aging and Alzheimer's disease. Language and Cognitive Processes, 10, 487– 539.Google Scholar
Bates E., & Wulfeck B. 1989 Crosslinguistic studies of aphasia. In B. MacWhinney & E. Bates (Eds.), The cross-linguistic study of sentence processing (pp. 328– 371). Cambridge: Cambridge University Press.
Bayles K., Tomoeda C. K., & Trosset M. W. 1992 Relation of linguistic communication abilities of Alzheimer's patients to stage of disease. Brain and Language, 42, 454– 472.Google Scholar
Bayles K. A. 1982 Language function in senile dementia. Brain and Language, 16, 265– 280.Google Scholar
Berndt R. S., Mitchum C. C., Haendiges A. N., & Sandson J. 1997 Verb retrieval in aphasia 2. Relationship to sentence processing. Brain and Language, 56, 107– 137.Google Scholar
Bock J. K. 1986a Meaning, sound and syntax: Lexical priming in sentence production. Journal of Experimental Psychology: Learning, Memory and Cognition, 12, 575– 586.Google Scholar
Bock J. K. 1986b Syntactic persistence in language production. Cognitive Psychology, 18, 355– 387.Google Scholar
Bock J. K. 1987 An effect of the accessibility of word forms on sentence structures. Journal of Memory and Language, 26, 119– 137.Google Scholar
Bock J. K., Loebell H., & Morey R. 1992 From conceptual roles to structural relations: Bridging the syntactic cleft. Psychological Review, 99, 150– 171.Google Scholar
Branigan H. P., & Pickering M. J. 1998 The representation of verbs: Evidence from syntactic priming in language production. Journal of Memory and Language, 39, 633– 651.Google Scholar
Bresnan J. 1982 The mental representation of grammatical relations. Cambridge, MA: MIT Press.
Bschor T., Kuehl K.-P., & Reischies F. M. 2001 Spontaneous speech of patients with dementia of the Alzheimer's type and mild cognitive impairment. International Psychogeriatrics, 13, 289– 298.Google Scholar
Bucks R. S., Singh S., Cuerden J. M., & Wilcock G. K. 2000 Analysis of spontaneous, conversational speech in dementia of the Alzheimer's type: Evaluation of an objective technique for analyzing lexical performance. Aphasiology, 14, 71– 91.Google Scholar
Chertkow H., & Bub D. 1990 Semantic memory loss in Alzheimer-type dementia. In M. Schwartz (Ed.), Modular deficits in Alzheimer-type dementia (pp. 207– 244). Cambridge, MA: MIT Press.
Chomsky N. 1982 Lectures on government and binding. New York: Foris.
Dunn L. M., Dunn L. M., Robertson G. J., & Eisenberg J. L. 1981 Peabody Picture Vocabulary Test—Revised. Circle Pines, MN: American Guidance Service.
Engle R. W., Kane M. J., & Tuholski S. W. 1999 Individual differences in working memory capacity and what they tell us about controlled attention, general fluid intelligence, and functions of the prefrontal cortex. In A. Miyake & S. Priti (Eds.), Models of working memory: Mechanisms of active maintenance and executive control (pp. 102– 134). New York: Cambridge University Press.
Ferreira F. 1994 Choice of passive voice is affected by verb type and animacy. Journal of Memory and Language, 33, 715– 736.Google Scholar
Ferreira V. S. 1996 Is it better to give than to donate? Syntactic flexibility in language production. Journal of Memory and Language, 35, 724– 755.Google Scholar
Folstein M. F., Folstein S. E., & McHugh P. R. 1975 Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189– 198.Google Scholar
Forbes K. E., Venneri A., & Shanks M. F. 2002 Distinct patterns of spontaneous speech deterioration: An early predictor of Alzheimer's disease. Brain and Cognition, 48, 356– 361.Google Scholar
Francis W. N., & Kucera H. 1982 Frequency analysis of English usage: Lexicon and grammar. Boston: Houghton–Mifflin.
Grossman M., Mickanin J., & Onishi K. 1996 Verb comprehension deficits in probable Alzheimer's disease. Brain and Language, 53, 369– 389.Google Scholar
Grossman M., Mickanin J., Onishi K., Robinson K. M., & D'Esposito M. 1997 Lexical acquisition in probable Alzheimer's disease. Brain and Language, 60, 443– 463.Google Scholar
Hier D. B., Hagenlocker K., & Shindler A. G. 1985 Language disintegration in dementia: Effects of etiology and severity. Brain and Language, 25, 117– 133.Google Scholar
Hodges J. R., Patterson K., Oxbury S., & Funnell E. 1992 Semantic dementia: Progressive fluent aphasia with temporal lobe atrophy. Brain, 115, 1783– 1806.Google Scholar
Hodges J. R., Salmon D., & Butters N. 1991 The nature of the naming deficit in Alzheimer's and Huntington's disease: The role of attention and memory. Brain, 114, 1547– 1558.Google Scholar
Huff F. J., Corkin S., & Growdon J. H. 1986 Semantic impairment and anomia in Alzheimer's disease. Brain and Language, 28, 235– 249.Google Scholar
Kane M. J., & Engle R. W. 2002 The role of prefrontal cortex in working-memory capacity, executive attention, and general fluid intelligence: An individual-differences perspective. Psychonomic Bulletin & Review, 9, 637– 671.Google Scholar
Kemper S. 1997 Metalinguistic judgments in normal aging and Alzheimer's disease. Journal of Gerontology, 52B, 147– 155.Google Scholar
Kemper S., Herman R. E., & Lian C. 2004 Age differences in sentence production. Manuscript submitted for publication.
Kempler D. 1991 Language changes in dementia of the Alzheimer type. In R. Lubinski (Ed.), Dementia and communication: Research and clinical implications. New York: Decker.
Kempler D., Almor A., MacDonald M. C., & Andersen E. S. 1999 Working with limited memory: Sentence comprehension in Alzheimer's disease. In S. Kemper & R. Kliegel (Eds.), Constraints on language: Aging, cognition and memory (pp. 227– 248). Boston: Kluwer Academic.
Kempler D., Almor A., Tyler L. K., Andersen E. S., & MacDonald M. C. 1998 Sentence comprehension deficits in Alzheimer's disease: A comparison of off-line and on-line sentence processing. Brain and Language, 64, 297– 316.Google Scholar
Kempler D., Curtiss D., & Jackson C. 1987 Syntactic preservation in Alzheimer's disease. Journal of Speech and Hearing Research, 30, 343– 350.Google Scholar
Kempler D., & Zelinski E. M. 1994 Language in dementia and normal aging. In F. A. Huppert, C. Brayne, & D. W. O'Connor (Eds.), Dementia and normal aging (pp. 331– 365). Cambridge: Cambridge University Press.
Kirschner H. S. 1982 Language disorders in dementia. In H. S. Kirschner & F. R. Freeman (Eds.), The neurology of aphasia (pp. 187– 196). Lisse, The Netherlands: Swets & Zeitlinger.
Levelt W. J. M. 1983 Monitoring and self-repair in speech. Cognition, 14, 41– 104.Google Scholar
Levelt W. J. M. 1989 Speaking: From intention to articulation. Cambridge: Cambridge University Press.
Levin B. 1993 English verb classes and alternations: A preliminary investigation. Chicago: University of Chicago Press.
MacDonald M. C., Almor A., Henderson V. W., Kempler D., & Andersen E. S. 2001 Assessing working memory and language comprehension in Alzheimer's disease. Brain and Language, 78, 17– 42.Google Scholar
Martin N., & Saffran E. M. 1996 Evidence for a common impairment affecting lexical processing and short-term memory in aphasia. Brain and Language, 55, 191– 194.Google Scholar
McDonald J. L., Bock K., & Kelly M. H. 1993 Word and world order: Semantic, phonological, and metrical determinants of serial position. Cognitive Psychology, 25, 188– 230.Google Scholar
McKhann G., Drachman D., Folstein M., Katzman R., Price D., & Stadlan E. M. 1984 Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Health and Human Services Task Force on Alzheimer's disease. Neurology, 34, 939– 944.Google Scholar
McRae K., Ferretti T. R., & Amoyte L. 1997 Thematic roles as verb-specific concepts. In M. C. MacDonald (Ed.), Lexical representations and sentence processing (pp. 137– 176). Hove, UK: Psychology Press.
Nebes R. D. 1989 Semantic memory in Alzheimer's disease. Psychological Bulletin, 106, 377– 394.Google Scholar
Nebes R. D., & Madden D. J. 1988 Different patterns of cognitive slowing produced by Alzheimer's disease and normal aging. Psychology and Aging, 3, 102– 104.Google Scholar
Nicholas M., Obler L., Albert M., & Helm–Estabrooks N. 1985 Empty speech in Alzheimer's disease and fluent aphasia. Journal of Speech and Hearing Research, 28, 405– 410.Google Scholar
Nicholas M., Obler L. A., Au R., & Albert M. L. 1996 On the nature of naming errors in aging and dementia: A study of semantic relatedness. Brain and Language, 54, 184– 195.Google Scholar
Nickles L. 1997 Spoken word production and its breakdown in aphasia. East Sussex: Psychology Press.
Ober B. A., & Shenaut G. K. 1999 Well-organized conceptual domains in Alzheimer's disease. Journal of the International Neuropsychological Society, 5, 676– 684.Google Scholar
Ober B. A., Shenaut G. K., & Reed B. R. 1995 Assessment of associative relations in Alzheimer's disease: Evidence for preservation of semantic memory. Aging and Cognition, 2, 254– 267.Google Scholar
Parasuranam R., & Haxby J. V. 1993 Attention and brain function in Alzheimer's disease: A review. Neuropsychology, 7, 242– 272.Google Scholar
Patel P. G., & Satz P. 1994 The language production system and senile dementia of the Alzheimer's type: Neuropathological implications. Aphasiology, 8, 1– 18.Google Scholar
Pinker S. 1997 Words and rules in the human brain. Nature, 387, 547– 548.Google Scholar
Pinker S., & Ullman M. T. 2002 The past and future of the past tense. Trends in Cognitive Sciences, 6, 456– 463.Google Scholar
Pye C., Cheung H., & Kemper S. 1992 Islands at eighty. In H. Goodluck & M. Rochemont (Eds.), Island constraints: Theory, acquisition and processing (pp. 351– 372). Dordrecht: D. Reidel.
Ripich D. N., & Terrell B. Y. 1987 Patterns of discourse cohesion and coherence in Alzheimer's disease. Journal of Speech and Hearing Disorders, 53, 8– 15.Google Scholar
Robinson K. M., Grossman M., White–Devine T., & D'Esposito M. 1996 Category-specific difficulty naming with verbs in Alzheimer's disease. Neurology, 47, 178– 182.Google Scholar
Schwartz M. F., Marin O. S. M., & Saffran E. M. 1979 Dissociations of language function in dementia: A case study. Brain and Language, 7, 277– 306.Google Scholar
Shenaut G. K., & Ober B. A. 1996 Methodological control of semantic priming in Alzheimer's disease. Psychology and Aging, 11, 443– 448.Google Scholar
Smith S., Faust M., Beeman M., Kennedy L., & Perry D. 1995 A property level analysis of lexical semantic representation in Alzheimer's disease. Brain and Language, 49, 263– 280.Google Scholar
Tanenhaus M. K., Carlson G. N., & Trueswell J. C. 1989 The role of thematic structures in interpretation and parsing. Language and Cognitive Processing, Parsing and Interpretation, 4, 211– 234.Google Scholar
Trueswell J. C. 1996 The role of lexical frequency in syntactic ambiguity resolution. Journal of Memory and Language, 35, 566– 585.Google Scholar
Wechsler D. 1987 Wechsler Memory Scale—Revised. New York: Psychological Corporation.
White–Devine T., Grossman M., Robinson K. M., Onishi K., Biassou N., & D'Esposito M. 1996 Verb confrontation naming and word-picture matching in Alzheimer's disease. Neuropsychology, 10, 495– 503.Google Scholar