Skip to main content Accessibility help
×
Home

Significant differences in fertility between dairy cows selected for one QTL located on bovine chromosome 3 are not attributable to energy balance, although eating behaviour is affected

  • S. Coyral-Castel (a1) (a2) (a3) (a4) (a5), P. Faverdin (a6) (a7), C. Ramé (a1) (a2) (a3) (a4), S. Fréret (a1) (a2) (a3) (a4), D. Guillaume (a1) (a2) (a3) (a4), S. Fritz (a8) and J. Dupont (a1) (a2) (a3) (a4)...

Abstract

Improvement of reproduction in dairy cows has become a major challenge in dairy production. We have recently shown that dairy cows carrying the ‘fertil−’ haplotype for one quantitative trait locus (QTL), affecting female fertility and located on the bovine chromosome 3, had a significantly lower conception rate after the first artificial insemination than cows carrying the ‘fertil+’ haplotype. The objective of this paper was to study other phenotypic modifications linked to this QTL. In the present study, 23 ‘fertil+’ and 18 ‘fertil−’ cows were characterized for live weight, milk production, food intake, eating behaviour and plasma metabolites. These parameters were measured during the first lactation, from calving to 40 weeks postpartum (wkpp). In the first 7 weeks of lactation, ‘fertil+’ primiparous cows had a significantly higher live BW and milk production than ‘fertil−’ cows. Dry matter intake tended to be slightly higher for ‘fertil+’ than for ‘fertil−’ primiparous cows in this period. However, energy balance was similar for the two haplotypes in the whole lactation, except in the first wkpp, and consequently, could not explain their different fertility. The major observation concerned the eating behaviour. ‘Fertil+’ primiparous cows had a significantly lower eating rate than ‘fertil−’ cows during the 40 weeks of lactation. In parallel, ‘fertil+’ cows spent significantly more time at the feeder for a similar number of visits than ‘fertil−’ cows. Furthermore, no differences in plasma concentrations of non-esterified fatty acids and insulin were observed between the two haplotypes. Plasma glucose was significantly lower in ‘fertil+’ than in ‘fertil−’ cows in the second wkpp. Taken together, our results show that ‘fertil+’ and ‘fertil−’ dairy cows, with different fertility, have also different eating behaviour without any variation in energy balance, except in the first week of lactation.

Copyright

Corresponding author

References

Hide All
Abrahamse, PA, Vlaeminck, B, Tamminga, S, Dijkstra, J 2008. The effect of silage and concentrate type on intake behavior, rumen function, and milk production in dairy cows in early and late lactation. Journal of Dairy Science 91, 47784792.
Accorsi, PA, Govoni, N, Gaiani, R, Pezzi, C, Seren, E, Tamanini, C 2005. Leptin, GH, PRL, insulin and metabolic parameters throughout the dry period and lactation in dairy cows. Reproduction in Domestic Animals 40, 217223.
Aeberhard, K, Bruckmaier, RM, Blum, JW 2001. Metabolic, enzymatic and endocrine status in high-yielding dairy cows – part 2. Journal of Veterinary Medicine Series A 48, 111127.
AFNOR 1997. Aliments des animaux-Dosage de l'azote-Méthode par combustion (DUMAS)-NF V18-120. Saint-Denis-La-Plaine, France.
Aufrère, J, Michalet-Doreau, B 1988. Comparison of methods for predicting digestibility of feeds. Animal Feed Science and Technology 20, 203218.
Azizi, O, Hasselmann, L, Kaufmann, O 2010. Variations in feeding behaviour of high-yielding dairy cows in relation to parity during early to peak lactation. Archiv Fur Tierzucht – Archives of Animal Breeding 53, 130140.
Azizi, O, Kaufmann, O, Hasselmann, L 2009. Relationship between feeding behaviour and feed intake of dairy cows depending on their parity and milk yield. Livestock Science 122, 156161.
Barbat, A, Le Mézec, P, Ducrocq, V, Mattalia, S, Fritz, S, Boichard, D, Ponsart, C, Humblot, P 2010. Female fertility in French dairy breeds: current situation and strategies for improvement. Journal of Reproduction and Development 56, S15S21.
Baumont, R 1996. Palatability and feeding behaviour in ruminants: a review. Annales de zootechnie 45, 385400.
Beam, SW, Butler, WR 1998. Energy balance, metabolic hormones, and early postpartum follicular development in dairy cows fed prilled lipid. Journal of Dairy Science 81, 121131.
Ben Jemaa, S, Fritz, S, Guillaume, F, Druet, T, Denis, C, Eggen, A, Gautier, M 2008. Detection of quantitative trait loci affecting non-return rate in French dairy cattle. Journal of Animal Breeding and Genetics 125, 280288.
Boichard, D, Grohs, C, Bourgeois, F, Cerqueira, F, Faugeras, R, Neau, A, Rupp, R, Amigues, Y, Boscher, MY, Leveziel, H 2003. Detection of genes influencing economic traits in three French dairy cattle breeds. Genetics Selection Evolution 35, 77101.
Busato, A, Faissler, D, Küpfer, U, Blum, JW 2002. Body condition scores in dairy cows: associations with metabolic and endocrine changes in healthy dairy cows. Journal of Veterinary Medicine Series A 49, 455460.
Butler, WR 2003. Energy balance relationships with follicular development, ovulation and fertility in postpartum dairy cows. Livestock Production Science 83, 211218.
Butler, WR 2005. Relationships of negative energy balance with fertility. In Advances in dairy technology, vol. 17 (ed. K Beauchemin), pp. 35–46.
Chagas, LM, Bass, JJ, Blache, D, Burke, CR, Kay, JK, Lindsay, DR, Lucy, MC, Martin, GB, Meier, S, Rhodes, FM, Roche, JR, Thatcher, WW, Webb, R 2007. New perspectives on the roles of nutrition and metabolic priorities in the subfertility of high-producing dairy cows. Journal of Dairy Science 90, 40224032.
Clapp, H 1937. A Factor in breeding efficiency of dairy cattle. Journal of Animal Science 1937, 259265.
Coyral-Castel, S, Brisard, D, Touze, JL, Dupont, M, Ramé, C, Uzbekova, S, Dupont, J 2012. Analysis of in vivo oocyte maturation, in vitro embryo development and gene expression in cumulus cells of dairy cows and heifers selected for one fertility QTL located on BTA3. Theriogenology 77, 18221833.
Coyral-Castel, S, Ramé, C, Monniaux, D, Fréret, S, Fabre-Nys, C, Fritz, S, Monget, P, Dupont, F, Dupont, J 2011. Ovarian parameters and fertility of dairy cows selected for one QTL located on BTA3. Theriogenology 75, 12391250.
Darwash, AO, Lamming, GE, Woolliams, JA 1999. The potential for identifying heritable endocrine parameters associated with fertility in post-partum dairy cows. Animal Science 68, 333347.
Dickinson, RL 1942. Techniques of conception control, 2nd edition. The Williams & Wilkins Co., Baltimore, Maryland.
Druet, T, Fritz, S, Boussaha, M, Ben-Jemaa, S, Guillaume, F, Derbala, D, Zelenika, D, Lechner, D, Charon, C, Boichard, D, Gut, IG, Eggen, A, Gautier, M 2008. Fine mapping of quantitative trait loci affecting female fertility in dairy cattle on BTA03 using a dense single-nucleotide polymorphism map. Genetics 178, 22272235.
Espe, D 1946. Secretion of milk, 3rd edition. The Collegiate Press, Ames, Iowa.
Friggens, NC, Nielsen, BL, Kyriazakis, I, Tolkamp, BJ, Emmans, GC 1998. Effects of feed composition and stage of lactation on the short-term feeding behavior of dairy cows. Journal of Dairy Science 81, 32683277.
Garnsworthy, PC, Sinclair, KD, Webb, R 2008. Integration of physiological mechanisms that influence fertility in dairy cows. Animal 2, 11441152.
Guillaume, F, Gautier, M, Ben Jemaa, S, Fritz, S, Eggen, A, Boichard, D, Druet, T 2007. Refinement of two female fertility QTL using alternative phenotypes in French Holstein dairy cattle. Animal Genetics 38, 7274.
Gutierrez, CG, Gong, JG, Bramley, TA, Webb, R 2006. Selection on predicted breeding value for milk production delays ovulation independently of changes in follicular development, milk production and body weight. Animal Reproduction Science 95, 193205.
Ingvartsen, KL, Andersen, JB 2000. Integration of metabolism and intake regulation: a review focusing on periparturient animals. Journal of Dairy Science 83, 15731597.
INRA 2007. Alimentation des bovins, ovins et caprins: Besoins des animaux – Valeurs des aliments (in French). editions QUAE c/o INRA, RD 10, 78026 Versailles cedex, Paris, France.
Jorritsma, R, Wensing, T, Kruip, TAM, Vos, PLAM, Noordhuizen, JPTM 2003. Metabolic changes in early lactation and impaired reproductive performance in dairy cows. Veterinary Research 34, 1126.
Kerestes, M, Faigl, V, Kulcsár, M, Balogh, O, Földi, J, Fébel, H, Chilliard, Y, Huszenicza, G 2009. Periparturient insulin secretion and whole-body insulin responsiveness in dairy cows showing various forms of ketone pattern with or without puerperal metritis. Domestic Animal Endocrinology 37, 250261.
Leroy, J, Vanholder, T, Van Knegsel, ATM, Garcia-Ispierto, I, Bols, PEJ 2008. Nutrient prioritization in dairy cows early postpartum: mismatch between metabolism and fertility? Reproduction in Domestic Animals 43, 96103.
López-Gatius, F, García-Ispierto, I, Santolaria, P, Yániz, J, Nogareda, C, López-Béjar, M 2006. Screening for high fertility in high-producing dairy cows. Theriogenology 65, 16781689.
Lucy, MC 2001. Reproductive loss in high-producing dairy cattle: where will it end? Journal of Dairy Science 84, 12771293.
Lucy, MC 2003. Mechanisms linking nutrition and reproduction in postpartum cows. Reproduction Supplement 61, 415427.
Oikonomou, G, Arsenos, G, Valergakis, GE, Tsiaras, A, Zygoyiannis, D, Banos, G 2008. Genetic relationship of body energy and blood metabolites with reproduction in Holstein cows. Journal of Dairy Science 91, 43234332.
Ospina, PA, Nydam, DV, Stokol, T, Overton, TR 2010. Associations of elevated nonesterified fatty acids and [beta]-hydroxybutyrate concentrations with early lactation reproductive performance and milk production in transition dairy cattle in the northeastern United States. Journal of Dairy Science 93, 15961603.
Pryce, JE, Royal, MD, Garnsworthy, PC, Mao, IL 2004. Fertility in the high-producing dairy cow. Livestock Production Science 86, 125135.
Rémond, B 1988. Changes in rumen contents over the 1st months of lactation in dairy cows. Reproduction Nutrition Development 28, 109110.
Roche, JF, Mackey, D, Diskin, MD 2000. Reproductive management of postpartum cows. Animal Reproduction Science 60–61, 703712.
Salazar-Ortiz, J, Camous, S, Briant, C, Lardic, L, Chesneau, D, Guillaume, D 2011. Effects of nutritional cues on the duration of the winter anovulatory phase and on associated 3 hormone levels in adult female Welsh pony horses (Equus caballus). Reproductive Biology and Endocrinology 9, 130.
SAS Institute Inc. 2009. SAS/STAT 9.2 user's guide, 2nd edition. SAS Institute Inc., Cary, NC.
Tolkamp, BJ, Schweitzer, DPN, Kyriazakis, I 2000. The biologically relevant unit for the analysis of short-term feeding behavior of dairy cows. Journal of Dairy Science 83, 20572068.
Van Soest, PJ, Robertson, JB, Lewis, BA 1991. Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. Journal of Dairy Science 74, 35833597.
Veerkamp, RF, Koenen, EPC, De Jong, G 2001. Genetic correlations among body condition score, yield, and fertility in first-parity cows estimated by random regression models. Journal of Dairy Science 84, 23272335.
Veerkamp, RF, Oldenbroek, JK, Van Der Gaast, HJ, Werf, JHJVD 2000. Genetic correlation between days until start of luteal activity and milk yield, energy balance, and live weights. Journal of Dairy Science 83, 577583.
Webb, R, Garnsworthy, PC, Gong, JG, Armstrong, DG 2004. Control of follicular growth: local interactions and nutritional influences. Journal of Animal Science 82, E63E74.

Keywords

Type Description Title
WORD
Supplementary materials

Coyral-castel Supplementary Material
Appendix

 Word (47 KB)
47 KB

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed