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Declining fertility in dairy cattle: changes in traditional and endocrine parameters of fertility

  • M. D. Royal (a1), A. O. Darwash (a1), A. P. F. Flint (a1), R. Webb (a1), J. A. Woolliams (a2) and G. E. Lamming (a1)...


Reproductive performance of 714 Holstein Friesian dairy cows was monitored between October 1995 and June 1998 using thrice weekly milk progesterone determinations. Defined endocrine parameters such as interval to post-partum commencement of luteal activity, inter-ovulatory interval and length of luteal and inter-luteal intervals were used with a number of traditional measures of reproductive performance to investigate the current status of fertility in a sample of United Kingdom dairy herds. A comparison of the results of the 1995 to 1998 trial with those of a previous (1975 to 1982) milk progesterone database, which included 2503 lactations in British Friesian cows monitored using a similar milk sampling protocol, revealed a decline infertility between these periods.

Between 1975-1982 and 1995-1998, pregnancy rate to first service declined from 55·6% to 39·7% (P < 0·001), at a derived average rate approaching 1% per year. This decline was associated with an increase (P < 0·001) in the proportion of animals with one or more atypical ovarian hormone patterns from 32% to 44%. There was a significant (P < 0·001) increase in the incidence of delayed luteolysis during the first cycle post partum (delayed luteolysis type I; 7·3% to 18·2%) and during subsequent cycles (delayed luteolysis type II; 6·4% to 16·8%), although the incidence of prolonged anovulation post partům (delayed ovulation type I; 10·9% to 12·9%) and prolonged inter-luteal intervals (delayed ovulation type II; 12·9% to 10·6%) did not alter significantly. These changes resulted in an increase in mean luteal phase length from 12·9 (s.e. 0·09) to 14·8 (s.e. 0·17) days and an increase in inter-ovulatory interval from 20·2 (s.e. 0·1) to 22·3 (s.e. 0·2) days. The decline infertility was also reflected in traditional measures of fertility since although interval to first service remained relatively unchanged (74·0 (s.e. 0·4) to 77·6 (s.e. 1·1) days) calving interval lengthened from 370 (s.e. 2·2) to 390 (s.e. 2·5) days. Collectively these changes may have contributed to the decline in pregnancy rates observed over the last 20 years.



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Agricultural and Food Research Council. 1993. Energy and protein requirements of ruminants. CAB International, Wallingford, UK.
Arendonk, J. A. M. van, Hovenier, R. and Boer, W. 1989. Phenotypic and genetic association between fertility and production in dairy cows. Livestock Production Science 21: 112.
Asdell, S. A., Dealba, J. and Roberts, S. J. 1949. Studies on the oestrous cycle of dairy cattle: cycle length, size of corpus luteum, and endometrial changes. Cornell Veterinarian 39: 389402.
Bagnato, A. and Oltenacu, P. A. 1993. Genetic studies of fertility traits and production in different parities in Italian Friesian cattle. Journal of Animal Breeding and Genetics 110: 126134.
Ball, P. J. H. and McEwan, E. E. A. 1998. The incidence of prolonged luteal function following early resumption of ovarian activity in postpartum dairy cows. Proceedings of the British Society of Animal Science, 1998, p. 187 (abstr.).
Beam, S. W. and Butler, W. R. 1998. Energy balance, metabolic hormones, and early postpartum follicular development in dairy cows fed prilled lipid. Journal of Dairy Science 81: 121131.
Beam, S. W. and Butler, W. R. 1999. Energy balance effects on follicular development and first ovulation in post-partum cows. Journal of Reproduction ami Fertility, Supplement 54: 411424.
Bulman, D. C. 1977. Progesterone levels and fertility of lactating cows. Ph.D. thesis, University of Nottingham.
Bulman, D. C. and Lamming, G. E. 1978. Milk progesterone levels in relation to conception, repeat breeding and factors influencing acyclicity in dairy cows. Journal of Reproduction and Fertility 54: 447458.
Bulman, D. C. and Wood, P. D. P. 1980. Abnormal patterns of ovarian activity in dairy cows and their relationships with reproductive performance. Animal Production 30: 177188.
Butler, W. R. and Smith, R. D. 1989. Interrelationships between energy balance and postpartum reproductive function in dairy cattle. Journal of Dairy Science 72: 767783.
Campos, M. S., Wilcox, C. J., Beceril, C. M. and Diz, A. 1994. Genetic parameters for yield and reproductive traits of Holstein and Jersey cattle in Florida. Journal of Dairy Science 77: 867873.
Darwash, A. O., Lamming, G. E. and Woolliams, J. A. 1997a. Estimation of genetic variation in the interval from calving to postpartum ovulation of dairy cows. Journal of Dairy Science 80: 12271234.
Darwash, A. O., Lamming, G. E. and Woolliams, J. A. 1997b. The phenotypic association between the interval to post-partum ovulation and traditional measures of fertility in dairy cattle. Journal of Animal Science 65: 916.
Darwash, A. O., Lamming, G. E. and Woolliams, J. A. 1999. The potential for identifying heritable endocrine parameters associated with fertility in postpartum dairy cows. Animal Science 68: 333347.
Erb, H. N., Smith, R. D., Oltenacu, P. A., Guard, C. L., Hillman, R. B., Powers, P. A., Smith, M. C. and White, M.E. 1985. Path model of reproductive disorders and performance, milk fever, mastitis, milk yield and culling in Holstein cows. Journal of Dairy Science 68: 33373349.
Esslemont, R.J. 1992. Measuring dairy herd fertility. Veterinary Record 131: 209212.
Esslemont, R. J. and Kossaibati, M. A. 1996. Decision support systems for fertility management in dairy herds: past, present and future. Proceedings of the Nottingham Cattle Fertility Conference, 17 th September.
Esslemont, R. J. and Peeler, E. J. 1993. The scope for raising margins in dairy herds by improving fertility and health. British Veterinary Journal 149: 537547.
Fonseca, E. A., Britt, J. H., McDaniel, B. T., Wilk, J. C. and Rakes, A. H. 1983. Reproductive traits of Holstein and Jerseys. Effects of age, milk yield and clinical abnormalities on involution of cervix and uterus, ovulation, oestrous cycles, detection of oestrus, conception rate and days open. Journal of Dairy Science 66: 11281147.
Foote, R. H. 1996. Review: dairy cattle reproductive physiology research and management — past progress and future prospects. Journal of Dairy Science 79: 980990.
Gaines, J. D., Thomas, C. B., and Eicker, S. 1993. The inter-oestrus interval profile of a dairy herd: how useful is it? Veterinary Medicine 88: 665671.
Gordon, I. 1996. Controlled reproduction in cattle and buffaloes. CAB International, UK.
Grosshans, T., Xu, Z. Z., Burton, L. J., Johnson, D. L. and Macmillan, K.L. 1997. Performance and genetic parameters for fertility of seasonal dairy cows in New Zealand. Livestock Production Science 51: 290297.
Hansen, L. B., Freeman, A. E. and Berger, P. J. 1983. Yield and fertility relationships in dairy cattle. Journal of Dairy Science 66: 293305.
Hoekstra, J., Lugt, A. W. van der, Werf, J. H. J. van der and Ouweljes, W. 1994. Genetic and phenotypic parameters for milk production and fertility traits in upgraded dairy cattle. Livestock Production Science 40: 225232.
Holmes, C. W., Grainger, C., Davey, A. W. F., Brookes, I. M., Ngarmsak, S. and Mitchell, K. D. 1987. Efficiency of milk production by Freisian cows of high or low breeding index. Proceedings of the fourth animal science congress of the Asian-Australasian Association of Animal Production Societies, Hamilton, New Zealand, p. 148.
Lamming, G. E. and Bulman, D. C. 1976. The use of milk progesterone radioimmunoassay in the diagnosis and treatment of subfertility in dairy cows. British Veterinary Journal 132: 507517.
Lamming, G. E. and Darwash, A. O. 1998. The use of milk progesterone profiles to characterise components of subfertility in milked dairy cows. Animal Reproduction Science 52: 175190.
Lucy, M. C., Staples, C. R., Thatcher, W. W., Erickson, P. S., Cleale, R. M., Firkins, J. L., Clark, J. H., Murphy, M. R. and Brodie, B. O. 1992. Influence of diet composition, dry-matter intake, milk production and energy balance on time of post-partum ovulation and fertility in dairy cows. Animal Production 54: 323331.
Macmillan, K. L., Lean, I. J. and Westwood, C. T. 1996. The effects of lactation on the fertility of dairy cows. Australian Veterinary Journal 73: 141147.
Milk Marketing Board. 1976. Dairy facts and figures. Milk Marketing Board, Thames Ditton, Surrey.
Nakao, T., Moriyoshi, M. and Kawata, T. 1992. The effect of postpartum ovarian dysfunction and endometritis on subsequent reproductive performance in high and medium producing dairy cows. Theriogenology 37: 341348.
Nash, J. G., Ball, L. and Olsen, J. D. 1980. Effects on reproductive performance of administration of GnRH to early postpartum dairy cows. Journal of Animal Science 50: 10171021.
National Dairy Council. 1997. Dairy facts and figures. National Dairy Council, 5-7 John Princes Street, London WIM OAP.
Nebel, R. L. and McGilliard, M. L. 1993. Interactions of high milk yield and reproductive performance in dairy cows. Journal of Dairy Science 76: 32573268.
Noakes, D. E., Wallace, L. M. and Smith, G. R. 1990. Pyometra in a Friesian heifer: bacteriological and endometrial changes. Veterinary Record 126: 509.
Oltenacu, P. A., Frick, A. and Lindhe, B. 1991. Relationship of fertility to milk yield in Swedish cattle. Journal of Dairy Science 74: 264268.
Opsomer, G., Corun, M., Deluyker, H. and deKruif, A. 1998. An analysis of ovarian dysfunction in high yielding dairy cows after calving based on progesterone profiles. Reproduction in Domestic Animals 33: 193204.
Poso, J. and Mantysaari, E. A. 1996. Genetic relationships between reproductive disorders, operational days open and milk yield. Livestock Production Science 46: 4148.
Pryce, J. E., Esslemont, R. J., Thompson, R., Veerkamp, R. F., Kossaibati, M. A. and Simm, G. 1998. Estimation of genetic parameters using health, fertility and production data from a management recording system for dairy cattle. Animal Science 66: 577584.
Pryce, J. E., Wilson, L. A. and Visscher, P. M. 1999. Effects of selection for production on maiden heifer fertility traits. Proceedings of the British Society of Animal Science, 1999, p. 49 (abstr.).
Pursley, J. R., Wiltbank, M. C., Stevenson, J. S., Ottobre, J. S., Garverick, H. A. and Anderson, L. L. 1997. Pregnancy rates per artificial insemination for cows and heifers inseminated at a synchronised ovulation or synchronised oestrus. Journal of Dairy Science 80: 295300.
Sauer, M. J., Foulkes, J. A., Worsfold, A. and Morris, B. A. 1986. Use of progesterone 11-glucuronide-alkaline phosphate conjugate in a sensitive microtitre-plate enzyme immunoassay of progesterone in milk and its application to pregnancy testing in dairy cattle. Journal of Reproduction and Fertility 76: 375391.
Savio, J. D., Boland, M. P. and Roche, J. F. 1990. Development of dominant follicles and length of ovarian cycles in postpartum dairy cows. Journal of Reproduction and Fertility 88: 581591.
Senatore, E. M., Butler, W. R. and Oltenacu, P. A. 1996. Relationships between energy balance and post-partum ovarian activity and fertility in first lactation dairy cows. Animal Science 62: 1723.
Smith, M. C. A. and Wallace, J. M. 1998. Influence of early post-partum ovulation on the re-establishment of pregnancy in multiparous and primiparous dairy cattle. Reproduction, Fertility and Development 10: 207216.
Smith, R. D., Pomerantz, A. J., Beai, W. E., McCann, J. P., Pilbeam, T. E. and Hansel, W. 1984. Insemination of Holstein heifers at a preset time after oestrous-cycle synchronization using progesterone and prostaglandin. Journal of Animal Science 58: 792800.
Staples, C. R., Thatcher, W. W. and Clark, J. H. 1990. Relationship between ovarian activity and energy status during the early post-partum period of high producing cows. Journal of Dairy Science 73: 938947.
Stevenson, J. S. and Britt, J. H. 1979. Relationships among luteinizing hormone, oestradiol, progesterone, glucocorticoids, milk yield, body weight and postpartum ovarian activity in Holstein cows. Journal of Animal Science 48: 570577.
Stevenson, J. S. and Call, E. P. 1983. Influence of early oestrus, ovulation, and insemination on fertility in postpartum Holstein dairy cows. Theriogenology 19: 367375.
Stott, A. W., Veerkamp, R. F. and Wassell, T. R. 1999. The economics of fertility in the dairy herd. Animal Science 68: 4957.
Thatcher, W. W., Meyer, M. D. and Danet-Desnoyers, G. 1995. Maternal recognition of pregnancy. Journal of Reproduction and Fertility, Supplement 49: 1528.
Thatcher, W. W. and Wilcox, C. J. 1973. Postpartum oestrus as an indicator of reproductive status in the dairy cow7 . Journal of Dairy Science 56: 608610.
Trimberger, G.W. 1954. Conception rates in dairy cattle from services at various intervals after parturition. Journal of Dairy Science 37: 10421049.
Veerkamp, R. F., Oldenbroek, J. K., Gaast, H. J. van der and Werf, J. H. J. van der. 2000. Genetic correlation between days until start of luteal activity and milk yield, energy balance and live weight. Journal of Dairy Science In press.
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Animal Science
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