Skip to main content Accessibility help
×
Home

Non-antibiotic approaches at drying-off for treating and preventing intramammary infections: a protocol for a systematic review and meta-analysis

  • David Francoz (a1), Vincent Wellemans (a1), Jean-Philippe Roy (a1) (a2), Pierre Lacasse (a2) (a3), Alfredo Ordonez-Iturriaga (a1), François Labelle (a4) and Simon Dufour (a2) (a5)...

Abstract

Intramammary infection (IMI) treatment and prevention at drying-off is one of the leading causes for using antimicrobials on dairy farms. The objective of the current paper is to describe the protocol used for conducting a systematic review of the literature on non-antibiotic strategies that can be used on dairy cows at dry off to treat and prevent IMI. Relevant literature will be identified using a combination of database search strategies and iterative screening of references. To be included in the review, articles will have to: (1) be published after 1969; (2) be written in English, French, or Spanish; (3) use a study design such as a controlled trial, an observational study, or an experimental study conducted in vivo; (4) be conducted on commercial dairy cows; (5) investigate a non-antibiotic intervention used at dry off; and finally, (6) report on a relevant mastitis outcome. Titles and abstracts, then full articles will be reviewed for inclusion. Specific data will be extracted and risk of bias will be assessed for all included articles. The planned systematic review will be the first to colligate, in a coherent whole, studies investigating non-antibiotic strategies for treating and preventing IMI at drying-off.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Non-antibiotic approaches at drying-off for treating and preventing intramammary infections: a protocol for a systematic review and meta-analysis
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Non-antibiotic approaches at drying-off for treating and preventing intramammary infections: a protocol for a systematic review and meta-analysis
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Non-antibiotic approaches at drying-off for treating and preventing intramammary infections: a protocol for a systematic review and meta-analysis
      Available formats
      ×

Copyright

Corresponding author

*Corresponding author. E-mail: simon.dufour@umontreal.ca

References

Hide All
Bradley, AJ and Green, MJ (2000). A study of the incidence and significance of intramammary enterobacterial infections acquired during the dry period. Journal of Dairy Science 83: 19571965.
Bradley, AJ and Green, MJ (2004). The importance of the nonlactating period in the epidemiology of intramammary infection and strategies for prevention. Veterinary Clinics of North America – Food Animal Practice 20: 547568.
Dohoo, I, Martin, W and Stryhn, H (2009). Veterinary Epidemiologic Research. Charlottetown, PE, Canada: VER Inc.
Grindlay, DJ, Brennan, ML and Dean, RS (2012). Searching the veterinary literature: a comparison of the coverage of veterinary journals by nine bibliographic databases. Journal of Veterinary Medical Education 39: 404412.
Guyatt, G, Oxman, AD, Akl, EA, Kunz, R, Vist, G, Brozek, J, Norris, S, Falck-Ytter, Y, Glasziou, P, Debeer, H, Jaeschke, R, Rind, D, Meerpohl, J, Dahm, P and Schunemann, HJ (2011). GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. Journal of Clinical Epidemiology 64: 383394.
Hektoen, L, Larsen, S, Odegaard, SA and Loken, T (2004). Comparison of homeopathy, placebo and antibiotic treatment of clinical mastitis in dairy cows – methodological issues and results from a randomized-clinical trial. Journal of Veterinary Medicine Series A 51: 439446.
Higgins, JPT and Green, S (2011). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. Cambridge, UK: The Cochrane Collaboration.
Klostermann, K, Crispie, F, Flynn, J, Ross, RP, Hill, C and Meaney, W (2008). Intramammary infusion of a live culture of Lactococcus lactis for treatment of bovine mastitis: comparison with antibiotic treatment in field trials. Journal of Dairy Research 75: 365373.
Kuipers, A, Koops, WJ and Wemmenhove, H (2016). Antibiotic use in dairy herds in the Netherlands from 2005 to 2012. Journal of Dairy Science 99: 16321648.
Mathie, RT and Clausen, J (2014). Veterinary homeopathy: systematic review of medical conditions studied by randomised placebo-controlled trials. Veterinary Record 175: 373381.
Mathie, RT and Clausen, J (2015). Veterinary homeopathy: systematic review of medical conditions studied by randomised trials controlled by other than placebo. BMC Veterinary Research 11: 236.
O'Connor, AM, Sargeant, JM and Wang, C (2014). Conducting systematic reviews of intervention questions III: Synthesizing data from intervention studies using meta-analysis. Zoonoses and Public Health 61 (Suppl. 1): 5263.
Pinedo, P, Karreman, H, Bothe, H, Velez, J and Risco, C (2013). Efficacy of a botanical preparation for the intramammary treatment of clinical mastitis on an organic dairy farm. Canadian Veterinary Journal 54: 479484.
Saini, V, Mcclure, JT, Léger, D, Dufour, S, Sheldon, AG, Scholl, DT and Barkema, HW (2012). Antimicrobial use on Canadian dairy farms. Journal of Dairy Science 95: 12091221.
Van Houwelingen, HC, Arends, LR and Stijnen, T (2002). Advanced methods in meta-analysis: multivariate approach and meta-regression. Statistics in Medicine 21: 589624.
Wells, G, Shea, B, O'connell, D, Peterson, J, Welch, V, Losos, M and Tugwell, P. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. [Available online at http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp] [Accessed July 12th 2016].

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed