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Theoretical Models in Twin Research*

  • L. Gedda (a1) and G. Brenci (a1)

Summary

The Authors show twin study to allow the determination of gene frequency and penetrance in the general population, by means of the analysis of distribution of phenotypic combinations in the twin pairs.

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Copyright

Footnotes

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Paper submitted to the Third International Congress of Human Genetics, Chicago (September 5-10th, 1966).

Footnotes

References

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Allen, G. (1952). The meaning of concordance and discordance in the estimation of penetrance and gene frequency. Amer. J. Hum. Genet., 4: 155172.
Allen, G. (1955). Comments on the analysis of twin samples. A.Ge.Me.Ge., II: 143161.
Dahlberg, G. (1923). Twin and heredity. Hereditas, 4: 27.
Gedda, L. (1951). Studio dei Gemelli. Ed. Orizzonte Medico, Roma.
Gedda, L., Brenci, G. (1962). Lo Studio dei Gemelli come Metodo di Ricerca in Genetica Umana. In Gedda, L.: De Genetica Medica, II. Ed. Istituto Mendel, Roma.
Huizinga, J., Heiden, J. A. (1957). The percentage of concordance in twins and mode of inheritance. A.Ge.Me.Ge., IV: 437451.
Kallmann, F. J. (1954). Twin data in the analysis of mechanisms of inheritance. Amer. J. Hum. Genet., 6: 157162.
Luxemburger, H. (1940). Die Zwillingsforschung als Methode der Erbforschung beim Menschen. In Just, G.: Handbuch der Erbbiologie des Menschen. Springer-Verlag, Berlin.
Stern, K. (1958). The ratio of monozygotic to dizygotic affected twins and the frequencies of affected twins in unselected data. A.Ge.Me.Ge., III: 313321.
Verschuer, O. v. (1949). Die Zwillingsforschung als Methode der Genetik vom Menschen. S.A.S. Bologna, 19: 23102.
Weinberg, W. (1901). Beiträge zur Physiologie und Pathologie der Mehrlingsgeburten beim Menschen. Arch. Ges. Physiol., 88: 346430.

Theoretical Models in Twin Research*

  • L. Gedda (a1) and G. Brenci (a1)

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