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Northwestern University Twin Study X: Outcome of Twin Gestations Complicated by Gestational Diabetes Mellitus

Published online by Cambridge University Press:  01 August 2014

J.D. Keller
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA
G.O. Utter
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA
S.L. Dooley
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA
J.P. Minogue
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA
L.G. Keith*
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois, USA
*
Department of Obstetrics and Gynecology, Northwestern University, 333 East Superior Street, Chicago, IL 60611, USA

Abstract

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Existing data concerning the effect of gestational diabetes on perinatal outcome in twin pregnancies is scant. We hypothesized that altered carbohydrate metabolism would worsen perinatal outcome in twin gestation in a manner similar to singleton gestation. Thirteen twin pregnancies complicated by gestational diabetes mellitus were matched by gestational age at delivery to 13 twin pregnancies unaffected by gestational diabetes. Comparing infants of diabetic mothers to infants of control mothers, there was a trend of greater likelihood of respiratory distress syndrome, hyperbilirubinemia, and prolonged neonatal intensive care nursery admissions. Our experience suggests that altered carbohydrate metabolism in multiple gestations increases the potential for neonatal morbidity.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1991

References

REFERENCES

1.Dickinson, JE, Palmer, SM (1990): Gestational diabetes: Pathophysiology and diagnosis. Sem Perinatol 14:211.Google Scholar
2.Fanaroff, AA, Martin, RJ, Miller, MJ (1989): Identification and management of high-risk problems in the neonate. In Creasy, RK, Resnick, R (eds): Maternal-Fetal Medicine: Principles and Practice. Philadelphia: WB Saunders Company, pp 11501191.Google Scholar
3.Kovacs, BW, Kirschbaum, TH, Paul, RH (1989): Twin gestations: I. Antenatal care and complications. Obstet Gynecol 74:313317.Google Scholar
4.Naidoo, L, Jailal, I, Moodley, J (1985): Intravenous glucose tolerance tests in women with twin pregnancy. Obstet Gynecol 66:500502.Google ScholarPubMed
5.O'Sullivan, JB, Mahan, CM (1964): Criteria for the oral glucose tolerance test in pregnancy. Diabetes 13:278285.Google ScholarPubMed
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