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Depression in schizophrenia and early psychosis: implications for assessment and treatment

  • Rachel Upthegrove

Summary

Depression in schizophrenia has been a neglected field for some time, but much evidence exists as to the common occurrence of affective disturbance in so-called non-affective psychosis. Depression is related to poor outcome in terms of functional recovery, relapse rate and suicide, and there is increasing evidence that it also precedes the onset of first-episode psychosis for many individuals. This article reviews recent steps forward in the evidence base for depression in schizophrenia in terms of prevalence, importance, assessment and treatment implications, with the aim of providing useful information for practising psychiatrists.

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Copyright

Corresponding author

Dr Rachel Upthegrove, Birmingham and Solihull Mental Health Trust, Early Intervention Service, 1 Miller Street, Aston, Birmingham B6 4NF, UK. Email: rachel.upthegrove@bsmht.nhs.uk

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Declaration of Interest

None.

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References

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Depression in schizophrenia and early psychosis: implications for assessment and treatment

  • Rachel Upthegrove
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