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Symptom profiles of natural and laboratory panic attacks

Published online by Cambridge University Press:  24 June 2014

K R J Schruers ,
H van de Mortel ,
T Overbeek  and
E Griez
K R J Schruers*
Affiliation:
Department of Psychiatry and Neuropsychology and Vijverdal Academic Anxiety Center, Maastricht University, Maastricht, the Netherlands
H van de Mortel
Affiliation:
Department of Psychiatry and Neuropsychology and Vijverdal Academic Anxiety Center, Maastricht University, Maastricht, the Netherlands
T Overbeek
Affiliation:
Department of Psychiatry and Neuropsychology and Vijverdal Academic Anxiety Center, Maastricht University, Maastricht, the Netherlands
E Griez
Affiliation:
Department of Psychiatry and Neuropsychology and Vijverdal Academic Anxiety Center, Maastricht University, Maastricht, the Netherlands
*
Department of Psychiatry and Neuropsychology and Vijverdal Academic Anxiety Center, Maastricht University, PO Box 88, 6200 AB Maastricht, the Netherlands. Tel: 0031 43 3685330; Fax: 0031 43 3685331; E-mail: koen.schruers@pn.unimaas.nl
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Abstract

Background:

Little accurate information is available about the symptomatology of real-life panic attacks and about how well they are reproduced by an experimental model such as the 35% CO2 challenge.

Method:

Real-life panic symptoms were assessed in a group of 67 panic disorder patients, using daily life monitoring. Panic symptoms elicited by a 35% CO2 challenge were assessed in 61 panic disorder patients, and their frequency was compared with the real-life symptoms.

Results:

The most frequent real-life symptoms were palpitations, dizziness and trembling. The 35% CO2 challenge reproduced well the majority of real-life symptoms.

Conclusion:

The findings suggest that the 35% CO2 challenge is a marker for spontaneous panic attacks, which are considered the core of panic disorder.

Keywords

carbon dioxidenaturalisticpanicsymptom
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 16 , Issue 2 , April 2004 , pp. 101 - 106
Copyright
Copyright © 2004 Blackwell Munksgaard

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