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Psychopathologie en Pathogenese van enkele behavioural phenotypes

Published online by Cambridge University Press:  18 September 2015

W.M.A. Verhoeven ,
S. Tuinier  and
L.M.G. Curfs
W.M.A. Verhoeven*
Affiliation:
Respectievelijk als zenuwarts/A-opleider en psychiater verbonden aan het Vincent van, Gogh Instituut te Venray
S. Tuinier
Affiliation:
Respectievelijk als zenuwarts/A-opleider en psychiater verbonden aan het Vincent van, Gogh Instituut te Venray
L.M.G. Curfs
Affiliation:
Als psycholoog werkzaam bij de Stichting Klinische Genetica te Maastricht
*
zenuwarts, Vincent van Gogh Instituut voor Psychiatrie, Stationsweg 46, 5803 AC Venray
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Summary

Description of psychopathological symptoms in mentally retarded subjects is of great heuristic value because of the association with a known genetic disorder as well as the heterogenous and atypical phenomenology. The concept of behavioural phenotypes postulates a specific relationship between gene defect and behaviour, although considerable overlap between syndromes and differences within syndromes concerning behavioural manifestations are frequently observed. Since syndrome specific psychiatric disorders can be established too, the term psychopathological phenotype seems to be appropriate.

Keywords

mental retardationbehavioural phenotypespsychopathological phenotypesbehavioural phenotypesverstandelijke handicapgenetische etiologie
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 10 , Issue 4 , December 1998 , pp. 87 - 89
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1998

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