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‘Pseudo-paraplegia': a chronic psychotic sequela of organophosphate exposure in schizophrenia

  • Ting-Gang Chang (a1) (a2), Wen-Yu Hsu (a1) (a2), Yen-Kuang Yang (a3) and Jui-Ting Liu (a1) (a2)

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Corresponding author

Jui-Ting Liu, MD Department of Psychiatry, Lu-Tung Branch of Changhua Christian Hospital, 888 Lu-Tung Road, Lu-Kang Town, Changhua County, Taiwan. Tel: +886 4 7789595 (ext. 1583); Fax: +886 4 7769780; E-mail: 400815@cch.org.tw

References

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3. Tan, DH, Peng, SQ, Wu, YL, Wang, YM, Lu, CF, Yan, CH. Chronic organophosphate (OP)-induced neuropsychiatric disorder is a withdrawal syndrome. Med Hypotheses 2009;72: 405406.
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5. Scarr, E, Dean, B. Role of the cholinergic system in the pathology and treatment of schizophrenia. Expert Rev Neurother 2009;9:7386.
6. Ali, SF, Hasan, M, Tariq, M. Levels of dopamine, norepinephrine & 5-hydroxytryptamine in different regions of rat brain & spinal cord following chronic administration of organophosphate pesticide dichlorvos. Indian J Exp Biol 1979;17:424426.
7. Geyer, MA, Vollenweider, FX. Serotonin research: contributions to understanding psychoses. Trends Pharmacol Sci 2008;29:445453.
8. Slotkin, TA, Seidler, FJ. Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems. Brain Res Bull 2007;72:232274.
9. Scarr, E. Muscarinic receptors in psychiatric disorders – can we mimic ‘health'? Neurosignals 2009;17:298310.
10. Bennouna, M, Greene, VB, Defranoux, L. Cholinergic hypothesis in psychosis following traumatic brain injury and cholinergic hypothesis in schizophrenia: a link? Encephale 2007;33:616620.

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