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Diagnosis and dimensional pharmacotherapy of challenging behaviour in mental retardation

  • W.M.A. Verhoeven and S. Tuinier


Classical psychiatric taxonomy appears to be increasingly inadequate in the diagnostic process of mentally retarded subjects. The reasons for this are the atypical presentation of classical psychiatric disorders, special diagnostic entities like cycloid psychosis and unstable mood disorder and the existence of so-called behavioural phenotypes related to syndromes with a known genetic etiology. In addition, disturbed behaviour may be the result of somatic or neurologic comorbidity and induced to adverse drug events.


Corresponding author

zenuwarts, Vincent van Gogh Instituut voor Psychiatrie, Stationsweg 46, 5803 AC Venray


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