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Depression, antidepressant treatment and the cardiovascular system

Published online by Cambridge University Press:  24 June 2014

Andrew Kemp*
Affiliation:
The School of Psychology, University of Sydney, Sydney, NSW, Australia and CADE Clinic, Discipline of Psychiatry, Sydney Medical School - Northern, The University of Sydney
*
Andrew Kemp, The School of Psychology, University of Sydney, Brennan MacCallum Building (A18), Sydney, NSW 2006, Australia. Tel: +61 2 93517585; Fax: +61 2 9036 5223; E-mail: andrew.kemp@sydney.edu.au

Abstract

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Type
Intervention Insights
Copyright
Copyright © Cambridge University Press 2011

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References

1.Dekker, JM et al. Low heart rate variability in a 2-minute rhythm strip predicts risk of coronary heart disease and mortality from several causes: the ARIC Study. Atherosclerosis risk in communities. Circulation 2000;102:12391244.CrossRefGoogle Scholar
2.Porges, S.The polyvagal theory: new insights into adaptive reactions of the autonomic nervous system. Cleve Clin J Med 2009;76(Suppl. 2):S86S90.CrossRefGoogle ScholarPubMed
3.Kemp, AH, Quintana, DS, Gray, MA, Felmingham, KL, Brown, K, Gatt, J.Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis. Biol Psychiatry 2010;67:10671074.CrossRefGoogle ScholarPubMed
4.Brown, ADH, Barton, DA, Lambert, GW.Cardiovascular abnormalities in patients with major depressive disorder: autonomic mechanisms and implications for treatment. CNS Drugs 2009;23:583602.CrossRefGoogle ScholarPubMed
5.Reid, S, Barbui, C.Long term treatment of depression with selective serotonin reuptake inhibitors and newer antidepressants. BMJ 2010;340:c1468.CrossRefGoogle ScholarPubMed
6.Hamer, M, Batty, GD, Seldenrijk, A, Kivimaki, M.Antidepressant medication use and future risk of cardiovascular disease: the Scottish Health Survey. Eur Heart J 2010. [Epub ahead of print; DOI: 10.1093/eurheartj/ehq438]Google ScholarPubMed
7.Richelson, E.Synaptic effects of antidepressants. J Clin Psychopharmacol 1996;16:1S7S.CrossRefGoogle ScholarPubMed
8.Licht, CMM, Geus, EJCD, Dyck, RV, Penninx, BWJH.Longitudinal evidence for unfavorable effects of antidepressants on heart rate variability. Biol Psychiatry 2010;68:861868.CrossRefGoogle ScholarPubMed
9.Kemp, AH, Quintana, DS, Malhi, GS.Effects of serotonin reuptake inhibitors on heart rate variability: methodological issues, medical comorbidity and clinical relevance. Biol Psychiatry (in press).Google Scholar
10.Belmaker, R, Agam, G.Major depressive disorder. N Engl J Med 2008;358:5568.CrossRefGoogle ScholarPubMed