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  • Print publication year: 2012
  • Online publication date: August 2012

5 - Developments of neuroimagingtechniques to diagnose and visualize white matter damage

from Section 1 - Traumatic Brain Injury

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1. Yanagawa Y , Tsushima Y , Tokumaru A , et al. A quantitative analysis of head injury using T2*-weighted gradient-echo imaging. J Trauma 2000;49(2):272–7.
2. Buki A , Povlishock JT . All roads lead to disconnection? Traumatic axonal injury revisited. Acta Neurochir (Wien) 2006;148(2):181–93; discussion 193–4.
3. Bennett M , O’Brien DP , Phillips JP , Farrell MA . Clinicopathologic observations in 100 consecutive patients with fatal head injury admitted to a neurosurgical unit. Ir Med J 1995;88(2):60–2, 59.
4. Graham DI , Adams JH , Murray LS , Jennett B . Neuropathology of the vegetative state after head injury. Neuropsychol Rehabil 2005;15(3–4):198–213.
5. Meythaler JM , Peduzzi JD , Eleftheriou E , Novack TA . Current concepts: diffuse axonal injury-associated traumatic brain injury. Arch Phys Med Rehab 2001;82(10):1461–71.
6. Haacke EM , Mittal S , Wu Z , Neelavalli J , Cheng YC . Susceptibility-weighted imaging: technical aspects and clinical applications, part 1. AJNR Am J Neuroradiol 2009;30(1):19–30.
7. Babikian T , Freier MC , Tong KA , et al. Susceptibility weighted imaging: neuropsychologic outcome and pediatric head injury. Pediatr Neurol 2005;33(3):184–94.
8. Akiyama Y , Miyata K , Harada K , et al. Susceptibility-weighted magnetic resonance imaging for the detection of cerebral microhemorrhage in patients with traumatic brain injury. Neurol Med Chir (Tokyo) 2009;49(3):97–9; discussion 99.
9. Wu Z , Li S , Lei J , An D , Haacke EM . Evaluation of traumatic subarachnoid hemorrhage using susceptibility-weighted imaging. AJNR Am J Neuroradiol 2010;31(7):1302–10.
10. Sigmund GA , Tong KA , Nickerson JP , et al. Multimodality comparison of neuroimaging in pediatric traumatic brain injury. Pediatr Neurol 2007;36(4):217–26.
11. Chastain CA , Oyoyo UE , Zipperman M , et al. Predicting outcomes of traumatic brain injury by imaging modality and injury distribution. J Neurotrauma 2009;26(8):1183–96.
12. Shen Y , Kou Z , Kreipke CW , Petrov T , Hu J , Haacke EM . In vivo measurement of tissue damage, oxygen saturation changes and blood flow changes after experimental traumatic brain injury in rats using susceptibility weighted imaging. Magn Reson Imaging 2007;25(2):219–27.
13. Newcombe VF , Williams GB , Nortje J , et al. Analysis of acute traumatic axonal injury using diffusion tensor imaging. Brit J Neurosurg 2007;21(4):340–8.
14. Song SK , Sun SW , Ramsbottom MJ , et al. Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 2002;17(3):1429–36.
15. Huppi PS , Dubois J . Diffusion tensor imaging of brain development. Semin Fetal Neonatal Med 2006; Sep 7.
16. Le Bihan D , Mangin JF , Poupon C , et al. Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 2001;13(4):534–46.
17. Newcombe V , Chatfield D , Outtrim J , et al. Mapping traumatic axonal injury using diffusion tensor imaging: correlations with functional outcome. PLoS One 2011;6(5):e19214.
18. Kraus MF , Susmaras T , Caughlin BP , et al. White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study. Brain 2007;130(Pt 10):2508–19.
19. Niogi SN , Mukherjee P , Ghajar J , et al. Extent of microstructural white matter injury in postconcussive syndrome correlates with impaired cognitive reaction time: a 3T diffusion tensor imaging study of mild traumatic brain injury. AJNR Am J Neuroradiol 2008;29(5):967–73.
20. Yasokawa YT , Shinoda J , Okumura A , et al. Correlation between diffusion-tensor magnetic resonance imaging and motor-evoked potential in chronic severe diffuse axonal injury. J Neurotrauma 2007;24(1):163–73.
21. Sidaros A , Engberg AW , Sidaros K , et al. Diffusion tensor imaging during recovery from severe traumatic brain injury and relation to clinical outcome: a longitudinal study. Brain 2007;131(2):559–72.
22. Niogi SN , Mukherjee P , Ghajar J , et al. Structural dissociation of attentional control and memory in adults with and without mild traumatic brain injury. Brain 2008;131(12):3209–21.
23. Newcombe VF , Outtrim JG , Chatfield DA , et al. Parcellating the neuroanatomical basis of impaired decision-making in traumatic brain injury. Brain 2011;134(3):759–68.
24. Le TH , Mukherjee P , Henry RG , et al. Diffusion tensor imaging with three-dimensional fiber tractography of traumatic axonal shearing injury: an imaging correlate for the posterior callosal “disconnection” syndrome: case report. Neurosurgery 2005;56(1):189.
25. Wang JY , Bakhadirov K , Devous MD , Sr., et al. Diffusion tensor tractography of traumatic diffuse axonal injury. Arch Neurol 2008;65(5):619–26.
26. Little DM , Kraus MF , Joseph J , et al. Thalamic integrity underlies executive dysfunction in traumatic brain injury. Neurology 2010;74(7):558–64.
27. Kasahara M , Menon DK , Salmond CH , et al. Altered functional connectivity in the motor network after traumatic brain injury. Neurology 2010;75(2):168–76.
28. Zhang K , Johnson B , Pennell D , et al. Are functional deficits in concussed individuals consistent with white matter structural alterations: combined FMRI & DTI study. Exp Brain Res 2010;204(1):57–70.
29. Cherubini A , Luccichenti G , Peran P , et al. Multimodal fMRI tractography in normal subjects and in clinically recovered traumatic brain injury patients. Neuroimage 2007;34(4):1331–41.
30. Monti MM , Vanhaudenhuyse A , Coleman MR , et al. Willful modulation of brain activity in disorders of consciousness. New Engl J Med 2010;362(7):579–89.
31. Vanhaudenhuyse A , Noirhomme Q , Tshibanda LJ , et al. Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients. Brain 2010;133(1):161–71.
32. Newcombe VF , Williams GB , Scoffings D , et al. Aetiological differences in neuroanatomy of the vegetative state: insights from diffusion tensor imaging and functional implications. J Neurol Neurosurg Psychiatry 2010;81(5):552–61.
33. Maudsley AA , Domenig C , Govind V , et al. Mapping of brain metabolite distributions by volumetric proton MR spectroscopic imaging (MRSI). Magn Reson Med 2009;61(3):548–59.
34. Govind V , Gold S , Kaliannan K , et al. Whole-brain proton MR spectroscopic imaging of mild-to-moderate traumatic brain injury and correlation with neuropsychological deficits. J Neurotrauma 2010;27(3):483–96.
35. Brooks WM , Stidley CA , Petropoulos H , et al. Metabolic and cognitive response to human traumatic brain injury: a quantitative proton magnetic resonance study. J Neurotrauma 2000;17(8):629–40.
36. Friedman SD , Brooks WM , Jung RE , et al. Quantitative proton MRS predicts outcome after traumatic brain injury. Neurology 1999;52(7):1384–91.
37. Holshouser BA , Tong KA , Ashwal S , et al. Prospective longitudinal proton magnetic resonance spectroscopic imaging in adult traumatic brain injury. J Magn Reson Imaging 2006;24(1):33–40.
38. Garnett MR , Blamire AM , Corkill RG , et al. Early proton magnetic resonance spectroscopy in normal-appearing brain correlates with outcome in patients following traumatic brain injury. Brain 2000;123(10):2046–54.
39. Shutter L , Tong KA , Lee A , Holshouser BA . Prognostic role of proton magnetic resonance spectroscopy in acute traumatic brain injury. J Head Trauma Rehabil 2006;21(4):334–49.
40. Bates TE , Strangward M , Keelan J , et al. Inhibition of N-acetylaspartate production: implications for 1H MRS studies in vivo. Neuroreport 1996;7(8):1397–400.
41. Bergsneider M , Hovda DA , McArthur DL , et al. Metabolic recovery following human traumatic brain injury based on FDG-PET: time course and relationship to neurological disability. J Head Trauma Rehab 2001;16(2):135–48.
42. Marcoux J , McArthur DA , Miller C , et al. Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury. Crit Care Med 2008;36(10):2871–7.
43. Condon B , Oluoch-Olunya D , Hadley D , Teasdale G , Wagstaff A . Early 1H magnetic resonance spectroscopy of acute head injury: four cases. J Neurotrauma 1998;15(8):563–71.
44. Hillary FG , Liu WC , Genova HM , et al. Examining lactate in severe TBI using proton magnetic resonance spectroscopy. Brain Injury 2007;21(9):981–91.
45. Ashwal S , Holshouser BA , Shu SK , et al. Predictive value of proton magnetic resonance spectroscopy in pediatric closed head injury. Pediatr Neurol 2000;23(2):114–25.
46. Aaen GS , Holshouser BA , Sheridan C , et al. Magnetic resonance spectroscopy predicts outcomes for children with nonaccidental trauma. Pediatrics 2010;125(2):295–303.
47. Marino S , Zei E , Battaglini M , et al. Acute metabolic brain changes following traumatic brain injury and their relevance to clinical severity and outcome. J Neurol Neurosurg Psychiatry 2007;78(5):501–7.
48. Yeo RA , Phillips JP , Jung RE , et al. Magnetic resonance spectroscopy detects brain injury and predicts cognitive functioning in children with brain injuries. J Neurotrauma 2006;23(10):1427–35.
49. Wu HM , Huang SC , Hattori N , et al. Subcortical white matter metabolic changes remote from focal hemorrhagic lesions suggest diffuse injury after human traumatic brain injury. Neurosurgery 2004;55(6):1306–15; discussion 1316–17.
50. Samson Y , Hantraye P , Baron JC , et al. Kinetics and displacement of [11C]RO 15–1788, a benzodiazepine antagonist, studied in human brain in vivo by positron tomography. Eur J Pharmacol 1985;110(2):247–51.
51. Kawai N , Maeda Y , Kudomi N , et al. Focal neuronal damage in patients with neuropsychological impairment after diffuse traumatic brain injury: evaluation using (11)c-flumazenil positron emission tomography with statistical image analysis. J Neurotrauma 2010;27(12):2131–8.
52. Lebel C , Walker L , Leemans A , Phillips L , Beaulieu C . Microstructural maturation of the human brain from childhood to adulthood. Neuroimage 2008;40(3):1044–55.
53. Suh DY , Davis PC , Hopkins KL , Fajman NN , Mapstone TB . Nonaccidental pediatric head injury: diffusion-weighted imaging findings. Neurosurgery 2001;49(2):309–18; discussion 318–20.
54. Dan B , Damry N , Fonteyne C , et al. Repeated diffusion-weighted magnetic resonance imaging in infantile non-haemorrhagic, non-accidental brain injury. Dev Med Child Neurol 2008;50(1):78–80.
55. Ichord RN , Naim M , Pollock AN , et al. Hypoxic-ischemic injury complicates inflicted and accidental traumatic brain injury in young children: the role of diffusion-weighted imaging. J Neurotrauma 2007;24(1):106–18.
56. Moseley IF . The neuroimaging evidence for chronic brain damage due to boxing. Neuroradiology 2000;42(1):1–8.
57. Hasiloglu ZI , Albayram S , Selcuk H , et al. Cerebral microhemorrhages detected by susceptibility-weighted imaging in amateur boxers. AJNR Am J Neuroradiol 2011;32:99–102.
58. Zhang L , Ravdin LD , Relkin N , et al. Increased diffusion in the brain of professional boxers: a preclinical sign of traumatic brain injury? AJNR Am J Neuroradiol 2003;24(1):52–7.
59. Zhang L , Heier LA , Zimmerman RD , Jordan B , Ulug AM . Diffusion anisotropy changes in the brains of professional boxers. AJNR Am J Neuroradiol 2006;27(9):2000–4.
60. Warden D. Military TBI during the Iraq and Afghanistan wars. J Head Trauma Rehabil 2006;21(5):398–402.
61. Owens BD , Kragh JF, Jr. , Wenke JC , et al. Combat wounds in operation Iraqi Freedom and operation Enduring Freedom. J Trauma 2008;64(2):295–9.
62. Cernak I , Noble-Haeusslein LJ . Traumatic brain injury: an overview of pathobiology with emphasis on military populations. J Cereb Blood Flow Metab 2009;30(2):255–66.
63. Peskind ER , Petrie EC , Cross DJ , et al. Cerebrocerebellar hypometabolism associated with repetitive blast exposure mild traumatic brain injury in 12 Iraq War veterans with persistent post-concussive symptoms. Neuroimage 2011;54(Suppl 1):S76–82.
64. Levin HS , Wilde E , Troyanskaya M , et al. Diffusion tensor imaging of mild to moderate blast-related traumatic brain injury and its sequelae. J Neurotrauma 2010;27(4):683–94.
65. Sponheim SR , McGuire KA , Kang SS , et al. Evidence of disrupted functional connectivity in the brain after combat-related blast injury. Neuroimage 2011;54(Suppl 1):S21–9.
66. Matthews SC , Strigo IA , Simmons AN , et al. A multimodal imaging study in U.S. veterans of Operations Iraqi and Enduring Freedom with and without major depression after blast-related concussion. Neuroimage 2011;54(Suppl 1):S69–75.