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Section 4 - Social Functioning and Mood

Published online by Cambridge University Press:  15 March 2019

Edited by
Carl I. Cohen  and
Paul D. Meesters
Carl I. Cohen
Affiliation:
SUNY Downstate Medical Center
Paul D. Meesters
Affiliation:
Friesland Mental Health Services
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Schizophrenia and Psychoses in Later Life
New Perspectives on Treatment, Research, and Policy
 , pp. 117 - 134
Publisher: Cambridge University Press
Print publication year: 2019

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References

References

Harvey, P.D. and Bellack, A. S. (2009). Toward a terminology for functional recovery in schizophrenia: Is functional remission a viable concept? Schizophrenia Bulletin, 35(2), 300–6.CrossRefGoogle Scholar
Priebe, S. (2007). Social outcomes in schizophrenia. British Journal of Psychiatry, 191(Suppl. 50), s15–20.CrossRefGoogle Scholar
Mueser, K.T. and Tarrier, N. (eds) Handbook of Social Functioning in Schizophrenia. Boston, MA: Allyn and Bacon, 1998, XI.Google Scholar
Bowie, C.R., Twamley, E.W., Anderson, H., et al. (2007). Self-assessment of functional status in schizophrenia. Journal of Psychiatric Research, 41(12), 1012–18.CrossRefGoogle ScholarPubMed
Cohen, C.I., Vahia, I., Reyes, P., et al. (2008). Schizophrenia in later life: clinical symptoms and social well-being. Psychiatric Services, 59(3), 232–4.CrossRefGoogle ScholarPubMed
Meesters, P.D., de Haan, L., Comijs, H.C., et al. (2012). Schizophrenia spectrum disorders in later life: prevalence and distribution of age at onset and sex in a dutch catchment area. American Journal of Geriatric Psychiatry, 20(1), 18–28.CrossRefGoogle Scholar
Meesters, P.D., Stek, M.L., Comijs, H.C., et al. (2010). Social functioning among older community-dwelling patients with schizophrenia: a review. American Journal of Geriatric Psychiatry, 18(10), 862–78.CrossRefGoogle ScholarPubMed
Ran, M.S., Xiang, M.Z., Conwell, Y., et al. (2004). Comparison of characteristics between geriatric and younger subjects with schizophrenia in community. Journal of Psychiatric Research, 38(4), 417–24.CrossRefGoogle ScholarPubMed
Ciompi, L. (1980). Catamnestic long-term study on the course of life and aging of schizophrenics. Schizophrenia Bulletin, 6(4), 606–18.CrossRefGoogle ScholarPubMed
Harding, C.M., Brooks, G.W., Ashikaga, T., Strauss, J.S. and Breier, A. (1987). The Vermont longitudinal study of persons with severe mental illness. II: Long-term outcome of subjects who retrospectively met DSM-III criteria for schizophrenia. American Journal of Psychiatry, 144(6), 727–35.Google ScholarPubMed
Meesters, P.D., Comijs, H.C., Sonnenberg, C.M., et al. (2014). Prevalence and correlates of depressive symptoms in a catchment-area based cohort of older community-living schizophrenia patients. Schizophrenia Research, 157(1–3), 285–91.CrossRefGoogle Scholar
Bankole, A., Cohen, C.I., Vahia, I., et al. (2008). Symptomatic remission in a multiracial urban population of older adults with schizophrenia. American Journal of Geriatric Psychiatry, 16(12), 966–73.CrossRefGoogle Scholar
Bowie, C.R., Reichenberg, A., Patterson, T., et al. (2006). Determinants of real-world functional performance in schizophrenia. American Journal of Psychiatry, 163(3), 418.CrossRefGoogle ScholarPubMed
Bowie, C.R., Leung, W.W., Reichenberg, A., et al. (2008). Predicting schizophrenia patients' real-world behavior with specific neuropsychological and functional capacity measures. Biological Psychiatry, 63(5), 505–11.CrossRefGoogle ScholarPubMed
Jeste, D.V., Twamley, E.W., Eyler Zorrilla, L.T., et al. (2003). Aging and outcome in schizophrenia. Acta Psychiatrica Scandinavica, 107(5), 336–43.CrossRefGoogle ScholarPubMed
Patterson, T.L., Semple, S.J., Shaw, W.S., et al. (1997). Self-reported social functioning among older patients with schizophrenia. Schizophrenia Research, 27(2–3), 199–210.CrossRefGoogle ScholarPubMed
Semple, S.J., Patterson, T.L., Shaw, W.S., et al. (1999). Self-perceived interpersonal competence in older schizophrenia patients: the role of patient characteristics and psychosocial factors. Acta Psychiatrica Scandinavica, 100(2), 126–35.CrossRefGoogle Scholar
Mueser, K.T., Pratt, S.I., Bartels, S.J., et al. (2010). Neurocognition and social skill in older persons with schizophrenia and major mood disorders: an analysis of gender and diagnosis effects. Journal of Neurolinguistics, 23(3), 297–317.CrossRefGoogle ScholarPubMed
Abdallah, C., Cohen, C.I., Sanchez-Almira, M., Reyes, P. and Ramirez, P. (2009). Community integration and associated factors among older adults with schizophrenia. Psychiatric Services, 60(12), 1642–8.CrossRefGoogle ScholarPubMed
Jimenez Madiedo, C., Garcia-Aracena, E.F., Ryu, H.H. and Cohen, C.I. (2012). Community integration in older adults with schizophrenia on 4-year follow-up. American Journal of Geriatric Psychiatry, 20, S91.Google Scholar
Cohen, C.I. and Iqbal, M. (2014). Longitudinal study of remission among older adults with schizophrenia spectrum disorder. American Journal of Geriatric Psychiatry, 22(5), 450–8.CrossRefGoogle ScholarPubMed
Kalache, S.M., Mulsant, B.H., Davies, S.J., et al. (2015). The impact of aging, cognition, and symptoms on functional competence in individuals with schizophrenia across the lifespan. Schizophrenia Bulletin, 41(2), 374–81.CrossRefGoogle ScholarPubMed
Pinkham, A.E., Kelsven, S., Kouros, C., Harvey, P.D. and Penn, D.L. (2017). The effect of age, race, and sex on social cognitive performance in individuals with schizophrenia. Journal of Nervous and Mental Disease, 205(5), 346–52.CrossRefGoogle ScholarPubMed
Smeets-Janssen, M.M.J., Meesters, P.D., Comijs, H.C., et al. (2013). Theory of mind differences in older patients with early-onset and late-onset paranoid schizophrenia. International Journal of Geriatric Psychiatry, 28(11), 1141–6.CrossRefGoogle ScholarPubMed
Wetherell, J.L., Palmer, B.W., Thorp, S.R., et al. (2003). Anxiety symptoms and quality of life in middle-aged and older outpatients with schizophrenia and schizoaffective disorder. Journal of Clinical Psychiatry, 64(12), 1476–82.Google ScholarPubMed
Holt-Lunstad, J., Smith, T.B. and Layton, J.B. (2010). Social relationships and mortality risk: a meta-analytic review. PLoS Medicine, 7(7), e1000316.CrossRefGoogle Scholar
Christensen, A.J., Dornink, R., Ehlers, S.L. and Schultz, S.K. (1999). Social environment and longevity in schizophrenia. Psychosomatic Medicine, 61(2), 141–5.CrossRefGoogle ScholarPubMed
Cohen, C.I. and Kochanowicz, N. (1989). Schizophrenia and social network patterns: a survey of black inner-city outpatients. Community Mental Health Journal, 25(3), 197–207.CrossRefGoogle ScholarPubMed
Cohen, C. (1993). Age-related correlations in patient symptom management strategies in schizophrenia: an exploratory study. International Journal of Geriatric Psychiatry, 8, 211–13.CrossRefGoogle Scholar
Leung, A. and Chue, P. (2000). Sex differences in schizophrenia, a review of the literature. Acta Psychiatrica Scandinavica, 101, 3–38.CrossRefGoogle Scholar
Vahia, I.V., Palmer, B.W., Depp, C., et al. (2010). Is late-onset schizophrenia a subtype of schizophrenia? Acta Psychiatrica Scandinavica, 122(5), 414–26.CrossRefGoogle ScholarPubMed
Palinkas, L.A, Criado, V., Fuentes, D., et al. (2007). Unmet needs for services for older adults with mental illness: comparison of views of different stakeholder groups. American Journal of Geriatric Psychiatry, 15, 530–40.CrossRefGoogle ScholarPubMed
Shepherd, S., Depp, C.A., Harris, G., et al. (2012). Perspectives on schizophrenia over the lifespan: a qualitative study. Schizophrenia Bulletin, 38(2), 295–303.CrossRefGoogle ScholarPubMed
Katschnig, H. (2000). Schizophrenia and quality of life. Acta Psychiatrica Scandinavica Supplementum, 102, 33–7.CrossRefGoogle Scholar
Awad, A.G. and Voruganti, L.N. (2012). Measuring quality of life in patients with schizophrenia: an update. Pharmacoeconomics, 30(3), 183–95.CrossRefGoogle ScholarPubMed
Voruganti, L., Heslegrave, R., Awad, A.G. and Seeman, M.V. (1998). Quality of life measurement in schizophrenia: reconciling the quest for subjectivity with the question of reliability. Psychological Medicine, 28, 165–72.CrossRefGoogle ScholarPubMed
Yanos, P.T. and Moos, R.H. (2007). Determinants of functioning and well-being among individuals with schizophrenia: an integrated model. Clinical Psychology Review, 27, 58–77.CrossRefGoogle ScholarPubMed
Ritsner, M.S., Lisker, A. and Arbitman, M. (2012). Ten-year quality of life outcomes among patients with schizophrenia and schizoaffective disorders: I. Predictive value of disorder-related factors. Quality of Life Research, 21(5), 837–47.Google ScholarPubMed
Slade, M., Leese, M., Cahill, S., Thornicroft, G. and Kuipers, E. (2005). Patient-rated mental health needs and quality of life improvement. British Journal of Psychiatry, 187, 256–61.CrossRefGoogle ScholarPubMed
Priebe, S., Reininghaus, U., McCabe, R., et al. (2010). Factors influencing subjective quality of life in patients with schizophrenia and other mental disorders: a pooled analysis. Schizophrenia Research, 121(1–3), 251–8.CrossRefGoogle ScholarPubMed
Folsom, D.P., Depp, C., Palmer, B.W., et al. (2009). Physical and mental health-related quality of life among older people with schizophrenia. Schizophrenia Research, 108(1–3), 207–13.CrossRefGoogle ScholarPubMed
Bankole, A.O., Cohen, C.I., Vahia, I., et al. (2007). Factors affecting quality of life in a multiracial sample of older persons with schizophrenia. American Journal of Geriatric Psychiatry, 15, 1015–23.CrossRefGoogle Scholar
Cohen, C.I., Vengassery, A. and Garcia Aracena, E.F. (2017). A longitudinal analysis of quality of life and associated factors in older adults with schizophrenia spectrum disorder. American Journal of Geriatric Psychiatry, 25(7), 755–65.CrossRefGoogle ScholarPubMed
Meesters, P.D., Comijs, H.C., de Haan, L., et al. (2013). Subjective quality of life and its determinants in a catchment area based population of elderly schizophrenia patients. Schizophrenia Research, 147(2–3), 275–80.CrossRefGoogle Scholar
Franz, M., Meyer, T., Reber, T. and Gallhofer, B. (2000). The importance of social comparisons for high levels of subjective quality of life in chronic schizophrenic patients. Quality of Life Research 9, 481–9.CrossRefGoogle ScholarPubMed
Reichstadt, J., Sengupta, G., Depp, C.A., Palinkas, L.A. and Jeste, D.V. (2010). Older adults’ perspectives on successful aging: qualitative interviews. American Journal of Geriatric Psychiatry, 18(7), 567–75.CrossRefGoogle ScholarPubMed
Ibrahim, F., Cohen, C.I. and Ramirez, P.M. (2010). Successful aging in older adults with schizophrenia: prevalence and associated factors. American Journal of Geriatric Psychiatry, 18(10), 879–86.CrossRefGoogle ScholarPubMed
Jeste, D.V., Savla, G.N., Thompson, W.K., et al. (2013). Association between older age and more successful aging: critical role of resilience and depression. American Journal of Psychiatry, 170, 188–96.CrossRefGoogle ScholarPubMed
Bartels, S.J. and Pratt, S.I. (2009). Psychosocial rehabilitation and quality of life for older adults with serious mental illness: recent findings and future research directions. Current Opinion in Psychiatry, 22(4), 381–5.CrossRefGoogle ScholarPubMed
Depla, M.F.I., de Graaf, R., van Weeghel, J. and Heeren, T.J. (2005). The role of stigma in the quality of life of older adults with severe mental illness. International Journal of Geriatric Psychiatry, 20, 146–53.CrossRefGoogle ScholarPubMed

References

Cohen, CI, Meesters, PD, Zhao, J. New perspectives on schizophrenia in later life: implications for treatment, policy and research, Lancet Psychiatry 2015; 2: 340–50.CrossRefGoogle ScholarPubMed
Meesters, PD, Comijs, HC, Sonnenberg, CM, et al. Prevalence and correlates of depressive symptoms in a catchment-area based cohort of older community-living schizophrenia patients, Schizophr Res 2014; 157: 285–91.CrossRefGoogle Scholar
Harris, EC, Barraclough, B. Suicide as an outcome for mental disorders: a meta-analysis, Br J Psychiatry 1997; 170: 205–28.CrossRefGoogle ScholarPubMed
Antonio, ED, Serper, MP. Depression and cognitive deficits in geriatric schizophrenia, Schizophr Res 2012; 134: 65–9.CrossRefGoogle ScholarPubMed
Kasckow, JW, Zisook, S. Co-occurring depressive symptoms in the older patient with schizophrenia, Drugs Aging 2008; 25: 631–47.CrossRefGoogle ScholarPubMed
Felmet, K, Zisook, S, Kasckow, JW. Elderly patients with schizophrenia and depression: diagnosis and treatment, Clin Schizophr Relat Psychoses 2011; 4: 239–50.CrossRefGoogle ScholarPubMed
Zisook, S, McAdams, LA, Kuck, J, et al. Depressive symptoms in schizophrenia, Am J Psychiatry 1999; 156: 1736–43.CrossRefGoogle ScholarPubMed
Kessler, RC, McGonagle, KA, Zhao, S, et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States, Arch Gen Psychiatry 1994; 51: 8–19.CrossRefGoogle ScholarPubMed
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Text Revision. 3. Washington, DC: American Psychiatric Association; 2000.Google Scholar
Roy, A. Suicide in chronic schizophrenia, Br J Psychiatry 1982; 141: 171–7.CrossRefGoogle ScholarPubMed
Johnson, DA. Studies of depressive symptoms in schizophrenia, Br J Psychiatry 1981; 139: 89–101.CrossRefGoogle ScholarPubMed
Diwan, S, Cohen, CI, Bankole, AO, et al. Depression in older adults with schizophrenia spectrum disorders: prevalence and associated factors, Am J Geriatr Psychiatry 2007; 15(12): 991–8.CrossRefGoogle ScholarPubMed
Ryu, HH, Cohen, CI. A longitudinal study of the outcome and associated factors of subsyndromal and syndromal depression in community-dwelling older adults with schizophrenia spectrum disorder, Am J Geriatr Psychiatry 2015; 23: 925–33.Google Scholar
Jack, T, Robert, RA. Psychiatry comorbidity among adults with schizophrenia: a latent class analysis, Psychiatry Res 2013; 210: 16–20.Google Scholar
Van Liempt, S, Dols, A, Schouws, S, Stek, ML, Meesters, PD. Comparison of social functioning in community-living older individuals with schizophrenia and bipolar disorder: a catchment area-based study, Int J Geriatr Psychiatry 2017; 32: 532–8.CrossRefGoogle ScholarPubMed
Bartels, SJ, Drake, RE. Depressive symptoms in schizophrenia: comprehensive differential diagnosis. Compr Psychiatry 1988; 29(5): 467–83.CrossRefGoogle ScholarPubMed
Leff, J. Depressive symptoms in the course of schizophrenia. In Depression in Schizophrenia, ed. DeLisi, LE, Washington, DC: American Psychiatric Press; 1990. 3–23.Google Scholar
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, DSM-V. Washington, DC: American Psychiatric Association; 2013.Google Scholar
Zisook, S, Montross, L, Kasckow, J, et al. Subsyndromal depressive symptoms in middle-aged and older persons with schizophrenia, Am J Geriatr Psychiatry 2007; 15(12): 1005–14.CrossRefGoogle ScholarPubMed
Graham, C, Arthus, A, Howard, R. The social functioning of older adults with schizophrenia, Aging Ment Health 2002; 6: 149–53.CrossRefGoogle ScholarPubMed
Centers for Disease Control and Prevention (CDC). Suicide facts at a glance 2015; stacks.cdc.gov/view/cdc/21865/cdc_21865_DS1.pdf (accessed October 2018).Google Scholar
Palmer, BA, Pankratz, VS, Bostwick, JM. The lifetime risk of suicide in schizophrenia: a reexamination, Arch Gen Psychiatry 2005; 62: 247–53.CrossRefGoogle ScholarPubMed
Kaskow, JW, Golshan, S, Zisook, S. Does age moderate the relationship between depressive symptoms and suicidal ideation in middle aged and older patients with schizophrenia and subthreshold depression? Am J Geriatr Psychiatry 2014: 22(5): 437–41.Google Scholar
Heilä, H, Isometsä, ET, Henriksson, MM, et al. Suicide and schizophrenia: a nationwide psychological autopsy study on age- and sex-specific clinical characteristics of 92 suicide victims with schizophrenia, Am J Psychiatry 1997; 154: 1235–42.Google Scholar
Cohen, CI, Abdallah, GC, Diwan, S. Suicide attempts and associated factors in older adults with schizophrenia, Schizophr Res 2010; 119: 253–7.CrossRefGoogle ScholarPubMed
Kasckow, J, Golshan, S, Zisook, S. Does age moderate the relationship between depressive symptoms and suicidal ideation in middle aged and older patients with schizophrenia and subthreshold depression? Am J Geriatr Psychiatry 2014; 22(5): 437–41.CrossRefGoogle ScholarPubMed
Kasckow, J, Montross, L, Golshan, S, et al. Suicidality in middle aged and older patients with schizophrenia and depressive symptoms: relationship to functioning and quality of life, Int J Geriatr Psychiatry 2007; 22: 1223–8.CrossRefGoogle ScholarPubMed
Erlangsen, A, Eaton, WW, Mortensen, PB, Conwell, Y. Schizophrenia: a predictor of suicide during the second half of life, Schizophr Res 2012; 134(2–3): 111–17.CrossRefGoogle ScholarPubMed
Roy, A. Family history of suicide, Arch Gen Psychiatry 1983; 40: 971–4.CrossRefGoogle ScholarPubMed
Cohen, CI, Vengassery, A, Aracena, EF. A longitudinal analysis of quality of life and associated factors in older adults with schizophrenia spectrum disorder, Am J Geriatr Psychiatry 2017; 25(7): 755–65.CrossRefGoogle ScholarPubMed
Bowie, CR, Reichenberg, A, Patterson, TL, Heaton, RK, Harvey, PD. Determinants of real-world functional performance in schizophrenia subjects: correlations with cognition, functional capacity, and symptoms, Am J Psychiatry 2006; 163(3): 418–25.CrossRefGoogle ScholarPubMed
Roseman, AS, Kasckow, J, Fellows, I, et al. Insight, quality of life, and functional capacity in middle-aged and older adults with schizophrenia, Int J Geriatr Psychiatry 2008; 23(7): 760–5.CrossRefGoogle ScholarPubMed
Siris, SG, Addington, D, Azorin, J, Calinescu, E. Depression in schizophrenia: recognition and management in the USA, Schizophr Res 2001; 47: 185–97.CrossRefGoogle ScholarPubMed
Helfer, B, Samara, TM, Huhn, M, et al. Efficacy and safety of antidepressants added to antipsychotics for schizophrenia: a systematic review and meta-analysis, Am J Psychiatry 2016; 173(9): 876–86.CrossRefGoogle ScholarPubMed
McEvoy, JP, Scheifler, PL, Frances, A. The Expert Consensus Guidelines Series: treatment of schizophrenia, J Clin Psychiatry 1999; 60(Suppl 11): 1–80.Google Scholar
Alexopoulos, GS, Streim, J, Carpenter, D, Docherty, JP; Expert Consensus Panel for Using Antipsychotic Drugs in Older Patients. Using antipsychotic agents in older patients, J Clin Psychiatry 2004; 65(Suppl 2): 5–99.Google ScholarPubMed
Micallef, J, Fakra, E, Blin, O. Use of antidepressant drugs in schizophrenic patients with depression, Encephale 2006; 32: 263–9.Google ScholarPubMed
Eiber, R, Even, C. Actual approaches to post-psychotic depression, Encephale 2001; 27(4): 301–7.Google ScholarPubMed
Hausmann, A, Fleischhacker, WW. Depression in patients with schizophrenia, CNS Drugs 2000; 14(4): 289–99.CrossRefGoogle Scholar
Kasckow, JW, Mohamed, S, Thallasinos, A, et al. Citalopram augmentation of antipsychotic treatment in older schizophrenia patients, Int J Geriatr Psychiatry 2001; 16(12): 1163–7.CrossRefGoogle ScholarPubMed
Zisook, S, Kasckow, JW, Golshan, S, et al. Citalopram augmentation for subsyndromal symptoms of depression in middle-aged and older outpatients with schizophrenia and schizoaffective disorder: a randomized controlled trial, J Clin Psychiatry. 2009; 70(4): 562–571.CrossRefGoogle ScholarPubMed
Kasckow, J, Lanouette, N, Patterson, T, et al. Treatment of subsyndromal depressive symptoms in middle-aged and older adults with schizophrenia: effect on functioning, Int J Geriatr Psychiatry 2010; 25(2): 183–90.CrossRefGoogle ScholarPubMed
Vahia, IV, Lanouette, NM, Golshan, S, et al. Adding antidepressants to antipsychotics for treatment of subsyndromal depressive symptoms in schizophrenia: impact on positive and negative symptoms, Indian J Psychiatry 2013; 55: 144–8.CrossRefGoogle ScholarPubMed
Nakajima, S, Takeuchi, H, Fervaha, G, et al. Comparative efficacy between clozapine and other atypical antipsychotics on depressive symptoms in patients with schizophrenia: analysis of the CATIE Phase 2E data, Schizophr Res 2015; 161: 429–33.CrossRefGoogle ScholarPubMed
Gareri, P, De Fazio, P, Russo, E, et al. The safety of clozapine in the elderly, Expert Opin Drug Saf 2008; 7(5): 525–38.CrossRefGoogle ScholarPubMed
Mueser, KT, Deavers, F, Penn, DL, Cassisi, JE. Psychosocial treatments for schizophrenia, Annu Rev Clin Psychol 2013; 9: 465–97.CrossRefGoogle ScholarPubMed

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