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Neurodegenerative Diseases
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Book description

Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.

Reviews

'This book is unique in its attempt to bring together basic and clinical information.'

Source: Doody's

'… there is a large amount of information, which will repay careful reading, perhaps especially for those new to the field. The book has high production values … a highly desirable addition for the departmental library.'

Source: Advances in Clinical Neuroscience and Rehabilitation

'Neurodegenerative Diseases is one of the most comprehensive books to appear on the subject in the past decade. … Neurodegenerative Disorders is a comprehensive, well-written textbook. It is an excellent reference to have and return to again and again as an authoritative source on neurodegeneration.'

Source: Journal of the American Medical Association

'The result is a good view, as of 2004, of the clinical and pathological features, pathophysiology, and prospects for the treatment of neurodegenerative diseases. The book is a weighty and comprehensive overview with an all-star list of contributors. … a good reference book for medical libraries, clinicians, and researchers who are new to the field. It may be particularly good as a textbook for students who need to get up to speed, for example, in a course on the biology of neurodegenerative diseases.'

Source: New England Journal of Medicine

'It covers all aspects of neurodegenerative diseases with good and extensive illustrations making it complete and helpful to clinicians and neuroscientists, and the editors are among the leading experts in the field of neurodegenerative diseases.'

Source: Neurosciences

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Contents


Page 1 of 3


  • 22 - Gene therapy
    pp 329-346
    • By Chamsy Sarkis, Laboratoire de Génétique Moléculaire de la Neurotransmission et des Processus, Neurodégénératifs (LGN) Centre National de la Recherche Scientifique UMR 7091, Hôpital Pitié-Salpétrière (Bâtiment CERVI), Paris, France, Jacques Mallet, Laboratoire de Génétique Moléculaire de la Neurotransmission et des Processus, Neurodégénératifs (LGN) Centre National de la Recherche Scientifique UMR 7091, Hôpital Pitié-Salpétrière (Bâtiment CERVI), Paris, France

Page 1 of 3


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