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  1. Home
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  3. Multiscale Modeling of Cancer
  • Cited by 159
Publisher:
Cambridge University Press
Online publication date:
October 2010
Print publication year:
2010
Online ISBN:
9780511781452
DOI:
https://doi.org/10.1017/CBO9780511781452
Subjects:
Engineering, Computer Science, Computational Biology and Bioinformatics, Biomedical Engineering
Information

Book description

Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.

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