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20 - Sedation in the Intensive Care Setting

Published online by Cambridge University Press:  22 November 2017

Richard D. Urman
Affiliation:
Harvard Medical School, Boston, MA, USA
Alan David Kaye
Affiliation:
Louisiana State University School of Medicine, New Orleans, LA, USA
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Publisher: Cambridge University Press
Print publication year: 2017

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References

References

Ely, EW, et al. Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA 2001; 286: 2703–10.CrossRefGoogle ScholarPubMed
Merriman, HM. The techniques used to sedate ventilated patients. A survey of methods used in 34 ICUs in Great Britain. Intensive Care Med 1981; 7: 217–24.CrossRefGoogle ScholarPubMed
Barr, J, et al. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med 2013; 41: 263306.CrossRefGoogle ScholarPubMed
Ouimet, S, Kavanagh, BP, Gottfried, SB, Skrobik, Y. Incidence, risk factors and consequences of ICU delirium. Intensive Care Med 2007; 33: 6673.CrossRefGoogle ScholarPubMed
Ely, EW, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004; 291: 1753–62.CrossRefGoogle ScholarPubMed
Sessler, CN, et al. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med 2002; 166: 1338–44.CrossRefGoogle ScholarPubMed
Coleman, RM, et al. The use of the bispectral index in the detection of pain in mechanically ventilated adults in the intensive care unit: a review of the literature. Pain Res Manag J Can Pain Soc 2015; 20: e33e37.CrossRefGoogle ScholarPubMed
Barr, J, Pandharipande, PP. The pain, agitation, and delirium care bundle: synergistic benefits of implementing the 2013 Pain, Agitation, and Delirium Guidelines in an integrated and interdisciplinary fashion. Crit Care Med 2013; 41: S99115.CrossRefGoogle Scholar
Cigada, M, et al. Sedation in the critically ill ventilated patient: possible role of enteral drugs. Intensive Care Med 2005; 31: 482–6.CrossRefGoogle ScholarPubMed
Goyal, S, Agrawal, A. Ketamine in status asthmaticus: a review. Indian J Crit Care Med Peer-Rev Off Publ Indian Soc Crit Care Med 2013; 17: 154–61.Google ScholarPubMed

Further Reading

Aitken, LM, et al. Protocol-directed sedation versus non-protocol-directed sedation to reduce duration of mechanical ventilation in mechanically ventilated intensive care patients. Cochrane Database Syst Rev 2015; 1: CD009771.Google ScholarPubMed
Aitken, LM, et al. Sedation protocols to reduce duration of mechanical ventilation in the ICU: a Cochrane Systematic Review. J Adv Nurs 2016; 72: 261–72.CrossRefGoogle ScholarPubMed
Barr, J, et al. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med 2013; 41: 263306.CrossRefGoogle ScholarPubMed
Brush, DR, Kress, JP. Sedation and analgesia for the mechanically ventilated patient. Clin Chest Med 2009; 30: 131–41, ix.CrossRefGoogle ScholarPubMed
Chanques, G, et al. Impact of systematic evaluation of pain and agitation in an intensive care unit. Crit Care Med 2006; 34: 1691–9.CrossRefGoogle Scholar
DAS-Taskforce 2015, et al. Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) – short version. Ger Med Sci GMS E-J 2015; 13: Doc19.Google Scholar
Ely, EW, et al. Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA 2001; 286: 2703–10.CrossRefGoogle ScholarPubMed
Girard, TD, et al. Delirium as a predictor of long-term cognitive impairment in survivors of critical illness. Crit Care Med 2010; 38: 1513–20.CrossRefGoogle ScholarPubMed
Pandharipande, PP, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007; 298: 2644–53.CrossRefGoogle Scholar
Rea, RS, Battistone, S, Fong, JJ, Devlin, JW. Atypical antipsychotics versus haloperidol for treatment of delirium in acutely ill patients. Pharmacotherapy 2007; 27: 588–94.CrossRefGoogle ScholarPubMed
Sessler, CN, Varney, K. Patient-focused sedation and analgesia in the ICU. Chest 2008; 133: 552–65.CrossRefGoogle ScholarPubMed
Sessler, CN, et al. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med 2002; 166: 1338–44.CrossRefGoogle ScholarPubMed
Strøm, T, Martinussen, T, Toft, P. A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial. Lancet Lond Engl 2010; 375: 475–80.Google ScholarPubMed

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